Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigate the proteome and phosphoproteome in a mouse model of PCa to identify signaling adaptations triggered by P

Extensive areas of old forests have declined all over the temperate regions of Europe mainly due to extensive forestry. This is likely to have negative impact on bats that roost in trees, such as the western barbastelle Barbastella barbastellus. We investigated its selection of summer roosts in a commercially used landscape in southern Sweden. We captured and radio-tracked 14 bats and found 17 occ

In September 1943, a Polish citizen Mieczyslaw Stachowiak, assigned with the German Wehrmacht’s Organisation Todt to Norway, left his detachment and escaped to Sweden. In the following two years he maintained contacts with no less than five diplomatic missions in Sweden – Britain, Germany, Japan, Spain and the United States – and provided them with false intelligence in return for money. In May 19

This article addresses the intricate and previously untold story of a German attempt in 1944 to have an agent, the Latvian Voldemar Blankenfelds, dispatched by boat, via Sweden, to South America where a German intelligence network was being established. Shortly after his arrival in Sweden in June 1944, however, Blankenfelds got in touch with the British diplomatic mission in Stockholm, told them o

The last 20 years have witnessed a marked increase in Swedish participation in major international UN-, EU- and/or NATO-led armed missions mandated according to Chapter VII of the UN Charter. This development reflects the new foreign and security priorities of Sweden in the wake of the end of the Cold War. Decisions on Swedish participation in such missions, however, cannot be taken without parlia

The chapter analyses three cases that all began as rape reports, but where seemingly greater dangers, such as “the HIV virus” and “the Internet”, were identified and prioritised over rape in the news. Consequently, the news media figures the HIV Man, Alexandra Man and Hotboy were introduced. Based on the overarching question “How is rape portrayed in the news media?” the objective is to analyse ho

Cultural aspects on Xenotransplantation and ethnographic fieldwork

The challenging synthesis of a fused C3-symmetric trilactam (1) was executed in racemic and enantiomerically pure form. The rigidity, symmetry and high density of hydrogen bonding motifs make 1 an attractive candidate for self-assembly study, which revealed different hydrogen bond patterns in the crystals of rac-1-d3 and (+)-(SSS)-1.

Biodiversity is in decline due to human-induced pressures on ecosystems around the world. To be able to counteract this alarming trend, it is paramount to closely monitor biodiversity at global scales. Because this is practically impossible with traditional methods, the last decade has seen a strong push for new solutions. In aquatic ecosystems, the monitoring of species from environmental DNA (eD

Construction of subway line intersection stations will become more and more popular in the future. Research on the deformation characteristics in the construction process is the best way to ensure the safety of the foundation pit itself, the surrounding buildings, and adjacent subway stations. In this paper, the deformation characteristics of a T-shaped subway foundation pit during construction ar

cBN-based materials are well known for their high chemical inertness and high performance. The variation of binder phase type and amount enable improvement of performance even more. Comprehensive investigation of the influence of type of niobium compound (NbC and NbN) as a binder phase for cBN-based materials were done. Samples were prepared by high pressure high temperature (HPHT) sintering under

Tillit till människors omdöme är grundläggande i demokratin och avgörande för att organisationer och samhällen ska bli framgångsrika. Särskilt viktig är tilliten till de medborgare och professioner som möts i kärnuppdraget. Genom att utgå från behoven i medborgarmötet, i stället för att detaljstyra på långt avstånd, kan den offentliga sektorn förbättra kvalitet, effektivitet och arbetsmiljö. Detta