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Checkpoint inhibition is an attractive option for treating bladder cancer, the tenth most common type of cancer in the world. With currently approved drugs restricted to targeting the PD1/PD-L1 axis with limited response rates, finding alternative targets for manipulation of immune cells could improve the survival of bladder cancer patients. Recently, cell markers selectively expressed by immunosu

Öresundspåren över Öresund utsätts för en allt högre utmaning i takt med att tågtrafiken på spåren ökar. Då befolkningen i Malmö och Köpenhamn ökar, ökar även antal resor och efterfrågan på resmöjligheter. Enligt en rapport från Öresundssmetro hemsida från 2019 har antalet pendlare mellan Malmö och Köpenhamn ökat kraftigt sedan Öresundsbron invigdes 2000. Mellan 2000 och 2018 ökade antalet pendlarThe Øresund tracks across the Øresund are facing an increasingly higher challenge as train traffic on the tracks continues to grow. As the population in Malmö and Copenhagen increases, the number of trips and demand for travel opportunities also grows. According to a report from the Øresund Metro website from 2019, the number of commuters between Malmö and Copenhagen has increased significantly si

This study investigates Swedish critical entities (CEs) ability to maintain function during up to three months of electricity supply disruptions. It also examines possible improvement measures, and how contextual cases (grey zone, heightened state of alert, war) influence CEs’ ability to maintain function during electricity supply disruptions. Expert elicitation was conducted with experts from eig

Sammanfattning Titel: Det lilla nordiska pusslet - En studie om långsiktig underavkastning efter nyemission Seminariedatum: 01/06-2023 Kurs: FEKH89 - Examensarbete i finansiering på kandidatnivå, 15 Högskolepoäng. Författare: Andreas Petterson, Hugo Rydberg, Marcus du Hane Handledare: Göran Anderson Nyckelord: SEO, nyemission, underavkastning,, abnormal avkastning, window of opportunity, småbolag

Vi människor påverkar miljön som vi lever i på en rad olika sätt. Tyvärr finns många exempel på mänskliga ”aktiviteter” som kan leda till negativa effekter på vår miljö. Den mest välkända orsaken till miljöförstöring är utsläpp av koldioxid till atmosfären som leder till en förhöjd medeltemperatur på vårt jordklot. Något som inte alls är lika självklart men som också kan påverka vår miljö negativPollutant emissions to the environment caused by human activity is a worldwide problem. This can occur due to residential fires which are often connected to loss of human lifes and belongings, as well as environmental damage. Residential fires canlead to emissions of pollutants that can be released to the air, water and soil. In this study, the level of soil contamination caused by residential fi

En analys av den samhälleligakunskapscirkulationen om prostituerade kvinnor i Sverige 1885-1900 genom att undersöka kunskapsarenor ämnade åt allmänheten - tidningsartiklar, skönlitterära verk samt ett medicinskt verk. Synen på prostituerade kvinnor samt hur dessa värderas och beskrivs undersöks.

Actinobacillus succinogenes is a microorganism is a very efficient producer of succinic acid, a chemical with a wide range of industrial applications. The bacterium is prone to form biofilm, a flocculation of cells attached to a surface. In this study, the bioproduction of succinic acid using Actinobacillus succinigenes 130Z was performed in microplate, bottle, and bioreactor systems to gain new i

This product was specifically designed for the astronauts at the ISS (International Space Station) who live in isolated and confined environments with no access to nature. As mission time increases, it becomes crucial to enable astronauts to "feel" nature again. The system consists of a fan+LED product (Micro-air) and a sensor. The fan is used to simulate natural wind, and the LEDs are

Syftet med detta arbete är att utarbeta en kvantitativ aspekt på ikoniska varumärken samt undersöka hur ett varumärkes ikoniska status påverkar deras brand equity. Genom att koppla ikoniska varumärken till brand equity utvecklas en mätbar aspekt av ikonicitet och dess påverkan. Kvantitativ undersökningsmetod med en enkätundersökning som kombinerar det positivistiska och subjektivistiska synsättet The purpose of this work is to develop a quantitative aspect of iconic brands and analyze how a brand's iconic status affects their brand equity. By linking iconic brands to brand equity, a measurable aspect of iconicity and its impact is developed. Quantitative research method with questionnaire survey that combines the positivist and subjectivist approach due to the complex idea of developin

Byggnadernas energianvändning utgör cirka 40% av den totala energianvändningen i Sverige. Byggbranschen står inför en stor utmaning att få ner denna energianvändning och klimatpåverkan. Detta blir inte enklare med stora befolkningsökning och stegrade markpriser i centralt läge som medför ytterligare krav på effektiv platsutnyttjande. För att kunna implementera en hållbar stadsutveckling bör både nThe aim of this study was to provide proposals for renovation measures and investigate to what extent preservation of cultural values can be combined with energy efficiency in an urban transformation projects. The goal was also to develop a strategy for the renovation of k-marked buildings using literature study, case study and parameter study. The case study was based on a 1910s industrial buildi

This research aims to investigate water-based varnishes and technologies to coat fiber-based closures to attain water barrier properties. To ensure recyclability the repulpability of coated and uncoated lids is tested. The research approach is exploratory. The investigation begins with the application of varnishes using a spray gun, brush, and dip coating followed by spraying equipment from Sprayi

Do municipalities in which organized crime is strongly established present lower Covid-19 vaccination rates, as a proxy for government trust? This paper aims to answer this question in the specific case of the Italian region of Sicily. Specifically, the analysis exploits a panel dataset of 390 Sicilian municipalities over 107 weeks (between the 27th of December 2020 and the 1st of January 2023) to

As part of a research grant aimed at producing chicken feed from the novel microalgae Scenedesmus sp., called the ReMAPP project, this thesis investigates opportunities to increase the conservation potential and protein digestibility utilizing solid-state lactic acid fermentation and commercial enzyme additives. The lactic acid fermentation mimics the traditional agricultural ensiling process, whe

In this paper the studied subject is the recent offshoot of incels: gymcels and associated terms such as sigma among others. This study investigates what this subsect implies and does so by defining aspects of conventional incel culture and juxtaposes these with gymcel cultures own differing ones. This includes values, morals, beliefs, concepts and the language used in this community to differ its

Frågeställningar: - Är det gynnsamt att byta till gröna tak på befintliga byggnader i tätbebyggda städer? - På vilket sätt gynnar gröna tak samhället? - Hur skiljer sig kostnaderna mellan ett traditionellt tak och ett grönt tak? - Varför läggs det inte gröna tak på befintliga byggnader i större omfattning? Syfte: Syftet med studien är att undersöka huruvida det är gynnsamt att byta taket på be

Tidigare forskning har visat att patienter inom vuxenpsykiatrisk vård utsätts för kränkningar av vårdpersonal, där dehumanisering och stigmatisering av psykisk sjukdom ses som bidragande faktorer. Denna studie ämnade undersöka om det fanns skillnader mellan anmälningar till Inspektionen för vård och omsorg (IVO) rörande kränkande bemötande jämfört med anmälningar rörande andra bemötandebrister, utPrevious research has shown that patients in adult psychiatric care are subject to abuse by healthcare staff, where dehumanization and stigmatization of mental illness are seen as contributing factors. This study aimed to investigate whether there were differences between reports to the Health and Social Care Inspectorate (IVO) concerning abusive treatment compared to reports concerning other trea

Lärdomar från småföretag som minskar sina utsläpp med Science Based Targets Vi vet alla hur viktigt det är att stoppa klimatförändringarna som sker, men ansvaret kanske inte alltid ligger på dig eller mig. Ofta fokuseras det på vad vi kan göra som individer, men alla problem hade inte löst sig även om vi slutade flyga eller åt mer vegetariskt. Omställningen måste även göras av företagen som stårWith climate change resulting from a history of uncontrolled greenhouse gas emissions, all parts of society now need to take action - maybe most importantly the private sector. Since 2015 the Science Based Targets (SBT) initiative has committed over 5000 companies worldwide to heavily reduce their total emissions at a pace that scientists deem necessary for average global temperature rise to stay

This thesis explores the underlying reasons for recent protests in Peru that began after the ousting of President Pedro Castillo in December of last year. The research is an explorative case study based on the thematic analysis of news articles. By drawing on decolonial theory, social movement theorising, as well as the concepts of identity and place, it examines the context of the protests and th

To accurately determine the efficiency and range of an electric vehicle, one must be able to estimate the rolling resistance of the car. This is currently done using standardized methods developed under laboratory settings, where transient aspects and effects of varying temperatures are excluded. Given the strong correlation between tyre temperatures and the rolling resistance, determining this te