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Advanced therapy medicinal products (ATMPs) are complex biological products that present specific scientific and regulatory challenges during clinical development. This thesis aimed to analyse consolidated Part I considerations raised during assessment of investigational ATMP clinical trial applications (CTAs) under the Clinical Trials Regulation (CTR) to identify recurring scientific and regulato
Title: Exploring Rush Order Policies in a Multi-Echelon Inventory System Authors: Stina Nilsson & Lina Solbu. Supervisors: Johan Marklund, LTH. Philip Mårtensson & Johan Lidvall, Volvo Group. Background: The Case Company is currently transitioning their inventory control from a single-echelon to a multi-echelon optimization approach. As no formal rush order policy currently exists, it i
Syftet med det här examensarbetet är att undersöka hur musiklärare och deras handlingsutrymme påverkas av olika ramfaktorer i kulturskolan. Det berör faktorer som byggnadens konstruktion och arkitektoniska förutsättningar, gehör från ledning, chefer och rektorer samt graden av spatial kompetens hos musiklärarna. Semistrukturerade intervjuer med ett kriteriebaserat urval ligger till grund för uThe purpose of this study is to investigate how the discretionary power varies amongst music teachers based on the different contextual factors in school of arts. The rules of conduct refers to the structure of the building and architectural constraints, the accommodation from managers and principals, and the spatial competence amongst music teachers. The data in this thesis is collected through s
This study aimed to investigate healthcare counselors’ experiences of providing psychosocial support for patients’ relatives and next of kin within different somatic healthcare settings, as well as the organisational conditions influencing this work. Furthermore, the study aimed to examine healthcare counselors’ discretion in relation to family support across different healthcare contexts. The stu
Extreme heat is not neutral. In Athens, the dense urban environment and harsh summer climate disproportionately impact the socio-economically marginalized. This research bridges the gap between climate data and human experience by uniting geospatial and qualitative survey data regarding heatwaves in Athens Municipality, with urban heat island research, vulnerability theory and climate justice. Sat
This master thesis focused on evaluating and designing the user interface of a camera production machine used in an industrial manufacturing environment. The project was conducted in collaboration with a global technology company and aimed to improve usability, clarity and operational support through a user-centered design approach. The work began with a comprehensive pre-study of the existing int
As buildings become more energy-efficient in their operation, the environmental costs of building components, such as carbon emissions during manufacturing, transportation, and end-of-life, are becoming increasingly significant. Automated façade shading systems have been widely proposed for their ability to reduce operational energy use and improve daylight performance. However, their life-cycle e
This thesis examines whether the AI Act and the transparency obligations of its Art. 50(2) and (4) are adequate to effectively address violations of the fundamental rights to privacy and data protection by nonconsensual pornographic deepfakes. To this end, the thesis first demonstrates how nonconsensual pornographic deepfakes infringe the rights to privacy and data protection as enshrined in Art.
Denna masteruppsats har som mål att utvärdera på vilket sätt nivån av presence inom virtuell verklighet (VR) påverkar användares prestation i en miljö när de ut- för uppgifter. Den utvärderar även hur mycket ansträngning som bör läggas för att göra VR-miljöer mer realistiska i forskningssammanhang. Denna studie genom- fördes i två primära delar; först en utvecklingsfas där en gedigen informationss
There exists a lack of laser-based remote sensing methods that give signals with high intensity and directionality. According to previous research, mirrorless lasing can meet these requirements; however, neither the dependence on the gain medium geometry nor the light-matter interaction responsible for the emission has been investigated in detail. This thesis project examined the sideways lasing e
The rapid expansion of the plant-based beverage sector has increased the demand for high-performance, barista-grade oat drinks that are capable of withstanding the thermal and acidic stresses of coffee applications. This master’s thesis, conducted in collaboration with Cerealiq AB, evaluates the efficacy of six specific enzymatic treatments in modifying the structural and physical properties of oa
20-25% of semi-natural habitat per square-kilometre is required for the provision of local Nature’s Contributions to People. Farmers are key actors in reversing the severe habitat deficits in agricultural regions. Conceptually anchored in the Safe and Just Earth System Boundary Framework and the Tripartite Framework for Mitigation Pathways, this thesis combines a systematic literature review on ho
The thesis explores the differences between the enforcement of State aid within the EU compared to the EEA EFTA States, in an effort to find out whether Iceland’s accession to the EU could affect the legal status of power purchase agreements entered into by Iceland’s National Energy Company, Landsvirkjun, and energy-intensive user. These agreements have already been reviewed by the EFTA Surveillan
This thesis analyses the structural limitations of the prevailing entitlement-based framework of international human rights law (IHRL), particularly in pluralistic and multicultural societies, and evaluates whether integrating duties alongside existing rights, a duty-infused reconceptualization, can address those limitations or not? The study draws its primary motivation from a structural crisis i
Cleanrooms in the pharmaceutical industry are energy-intensive environments where HVAC systems account for roughly 50-75% of energy use due to high air changes per hour and strict conditioning requirements for indoor humidity and temperature. This thesis presents a techno-economic analysis comparing two of the most common HVAC system types. These systems are centralized, using one large AHU to pro
Post-quantum cryptography increases the computational and data-movement demands placed on embedded processors. Many standardized and candidate schemes rely heavily on Keccak, SHA-3, and SHAKE operations, where the 1600-bit Keccak state is repeatedly updated and may become a bottleneck when accelerated through software-hardware interaction. This thesis presents a direct memory access (DMA)-enhanced
The United Nations Convention on Contracts for the International Sale of Goods (CISG) serves as the preeminent uniform legal framework governing international sales. Central to its application is Article 8, which prescribes a tripartite hierarchy for interpreting party intent by prioritizing subjective intent, applying the objective reasonable person standard, and mandating a holistic review of al
As wireless communication systems evolve toward 6G and joint communication and sensing paradigms, emerging applications impose stringent low-latency constraints on target tracking systems. Within the hardware implementation of particle filters, the traditional systematic resampling algorithm suffers from global data dependencies and sequential memory accesses, creating a fundamental performance bo
This thesis aims to deepen the understanding of women’s entrepreneurship in Skåne, Sweden, and to examine how entrepreneurial support organizations (ESOs) contribute to overcoming barriers in the business development process. Using a mixed-methods approach, including two literature reviews, four in-depth interviews, and a quantitative questionnaire, the study applies triangulation of empirical inf
