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A microcalorimetric vessel for monitoring cytotoxic reactions in the micro-submicrowatt region

A microcalorimetric vessel for monitoring the initial phases of cytotoxic reactions in the micro-submicrowatt region has been designed and tested. The vessel is intended to be used witha multichannel microcalorimetric system from Thermometric, Järfälla, Sweden and can be built up stepwise in a modular way. The different functions of perfusion, stirring and addition of small amounts of soluble immu

A Comparison of tumor demarcation potential for various hematoporphyrin derivatives and phtalocyanine using laser-induced fluorescence

Laser-induced fluorescence data for rats injected with the different tumor-marking drugs, dihematoporphyrin ether, poly hematoporphyrin esters, hematoporphyrin and phtalocyanine, are presented. Studies were performed at two different excitation wavelengths. Comparisons between the different drugs are made with regard to fluorescence intensity and tumor demarcation capability. Further, the origin o

Use of microcalorimetry in analysing the kinetics of ADCC

Microcalorimetry was found to be a useful technique for the demonstration of antibody-dependent cellular cytotoxicity (ADCC) against human melanoma cells mediated by a heterologous rabbit antiserum and two monoclonal antibodies in combination with human peripheral blood lymphocytes as effector cells. The rabbit antiserum and the monoclonal IgG3 antibody 2B2 directed against the GD3 ganglioside exp

Demonstration of antibodies binding to autologous and allogeneic leukemic cells in childhood ALL - Evidence for a common ALL antigen(s)

The humoral immune response to autologous leukemic cells was investigated in childhood ALL using a 125I protein A binding assay. In 5/7 patients antibodies were demonstrated at diagnosis and in 3/7 cases also after chemotherapy. Sera from 2/3 patients, which bound significantly to autologous leukemic cells, did not bind significantly to autologous remission cells. In allogeneic experiments sera bo

Fewer Community-Acquired Colds with Daily Consumption of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2. A Randomized, Placebo-Controlled Clinical Trial

BACKGROUND: Viral infections of the upper airways are the most common cause for absence from work or school, and there is evidence for probiotic efficacy in reducing the incidence and severity of these infections.OBJECTIVES: We aimed to confirm the previously reported beneficial effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 against community-acquired common

Inhibition of platelet aggregation by myeloid leukaemic cells demonstrated in vitro

The effect of myeloid leukaemic cells, cells of the promyelocytic cell line HL-60 and normal polymorphonuclear granulocytes (PMN), enclosed in dialysis tubes, on the aggregation of allogeneic normal platelets after induction with arachidonic acid (AA) and with adenosine diphosphate (ADP) was investigated in vitro. Inhibition of aggregation was seen after preincubation of the platelets with leukaem

Landscape Theology : Exploring the Outfields of the Telemarkian Dream Song

The article explores the Norwegian ‘national ballad’ Draumkvæde (the Dream Song) in Maren Ramskeid’s version. This work has traditionally been interpreted as a folklore adaptation of medieval visionary literature such as the Vision of Tundale, related to Dante Alighieri’s Divine Comedy. The ballad, however, lacks demons and devils and infernal torture – it is even almost completely devoid of humanThe article explores the Norwegian ‘national ballad’ Draumkvæde (the Dream Song) in Maren Ramskeid’s version. This work has traditionally been interpreted as a folklore adaptation of medieval visionary literature such as the Vision of Tundale, related to Dante Alighieri’s Divine Comedy. The ballad, however, lacks demons and devils and infernal torture – it is even almost completely devoid of human

Rapport 14:2020. Situationen under COVID-19 pandemin för 7 781 hälso- och sjukvårdsanställda : enkätsvar vid uppföljningsstudien Hållbart arbetsliv inom hälso och sjukvården 2020

Covid-19 innebär en extrem utmaning för den svenska sjukvården. Denna rapport är en sammanställning utifrån en enkätstudie med sjukvårdsanställda om deras arbetsförhållande, upplevelse av smittskydd, om organisationens ledningsarbete, arbetsmiljö, sin hälsa, etc. under Covid-19 pandemin september - december 2020.Studien ingår i en longitudinellt projekt där den första mätningen gjordes våren med s

Romania at Lund University

The volume encompasses six conferences of Romanian academics (from Bratislava, Skopje, Bucharest, Iași and Alba Iulia) invited to Lund to hold conferences in English and French as part of Romanian language and literature research seminar series in the interval September 2015 – March 2017 on various topics: linguistics and etymology, literary world’s specificities, contemporary Romanian literature,

Low kilovoltage computed tomography to reduce contrast medium dose in patients at risk of acute kidney injury

Background: Patients with reduced renal function may be at risk of contrast medium-induced acute kidney injury (CI-AKI) following intravenous iodine contrast medium (CM) enhanced computed tomography (CT). Reducing the CM dose may reduce this risk. Decreasing the X-ray tube potential (kilovoltage, kV) from commonly used 120 to 80 kV results in higher CM attenuation due to the photoelectric properti

Can iterative reconstruction algorithms replace tube loading compensation in low kVp hepatic CT? : Subjective versus objective image quality

Background: Hepatic computed tomography (CT) with decreased peak kilovoltage (kVp) may be used to reduce contrast medium doses in patients at risk of contrast-induced acute kidney injury (CI-AKI); however, it increases image noise. To preserve image quality, noise has been controlled by X-ray tube loading (mAs) compensation (TLC), i.e. increased mAs. Another option to control image noise would be

Administrative Constitutional Review in Sweden: Between Subordination and Independence

The article examines the power of administrative bodies to assess the constitutionality of legislation (‘administrative constitutional review’), taking examples from Swedish public law. The Swedish constitution explicitly requires all public bodies to engage in administrative constitutional review when necessary. In this way, Swedish administrative authorities have the right and duty to act as gua

Alignment of the ATLAS Inner Detector in Run 2

The performance of the ATLAS Inner Detector alignment has been studied using pp collision data at s=13TeV collected by the ATLAS experiment during Run 2 (2015–2018) of the Large Hadron Collider (LHC). The goal of the detector alignment is to determine the detector geometry as accurately as possible and correct for time-dependent movements. The Inner Detector alignment is based on the minimization

Identification and Quantification of Chemical Forms of Cu and Zn in MSWI Ashes Using XANES

Incineration is in many countries a common treatment method for municipal solid waste, and utilization of the ash residues has attracted significant interest. The bottom ash is best suited as a secondary construction material, whereas the fly ash is being investigated as a secondary raw material for recovery of, for example, Zn, Cu, and salts. For both types of application, knowledge about the che

Making Lab Sessions Mandatory-On Student Work Distribution in a Gamified Project Course on Market-Driven Software Engineering

Unfair work distribution in student teams is a common issue in project-based learning. One contributing factor is that students are differently skilled developers. In a course with group work intertwining engineering and business aspects, we designed an intervention to help novice programmers, i.e., we introduced mandatory programming lab sessions. However, the intervention did not affect the work

Does neighborhood alcohol availability moderate the impact of familial liability and marital status on risk for alcohol use disorders? A Swedish national study

Objective: The purpose of this study was to determine whether ease of access to alcohol at the neighborhood level moderates the impact of familial liability and marital status on risk for alcohol use disorder (AUD). Method: Individuals in Sweden were divided into those residing in a neighborhood with (n = 14.1%) versus without (n = 85.9%) an alcohol outlet (bars/nightclubs or government stores). A