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Background: Tyrosine kinase inhibitors (TKIs) have improved the survival of patients with chronic myeloid leukaemia. Many patients have deep molecular responses, a prerequisite for TKI therapy discontinuation. We aimed to define precise conditions for stopping treatment. Methods: In this prospective, non-randomised trial, we enrolled patients with chronic myeloid leukaemia at 61 European centres i
A mixed-domain device characterisation algorithm with is proposed and evaluated. Wideband signals from a time-domain wavelet generator are applied to millimetre-wave antennas. Deliberately chosen gating techniques in time- A nd frequency-domain are used to relax the calibration effort to one reference measurement. A frequency-domain gate shapes the excitation pulse. Selective removal of setup arte
PURPOSE: When a woman is diagnosed with breast cancer, it affects all family members. Therefore, the aim of this study was to elucidate family members lived experience when a family member is diagnosed with breast cancer.METHOD: The study had a hermeneutic phenomenological design including individual conversational interviews conducted face-to-face with six women with breast cancer and their famil
A detailed chemical kinetic mechanism comprising methyl acetate and ethyl acetate has been developed based on the previous work by Westbrook et al. [1]. The newly developed kinetic mechanism has been updated with new reaction rates from recent theoretical studies. To validate this model, shock tube experiments measuring ignition delay time have been conducted at 15 & 30 bar and equivalence rat
This paper examines the life-cycle dynamics of real wages and labor supply in Sweden. The descriptive results lend support to the inter-temporal substitution hypothesis (ISH), as the age patterns of real wages and the labor supply are both hump-shaped. However, the age-wage profiles increasingly shift toward older ages over time, whereas the age-employment profiles do not. This leads to an accentu
We studied the at-sea distribution of two auks (Common Murre Uria aalge, Razorbill Alca torda), two gulls (Lesser Black-backed Gull Larus fuscus, Herring Gull Larus argentatus), and Great Cormorant Phalacrocorax carbo during the peak breeding season of 2014 around Stora Karlsö, the main Baltic Sea seabird colony. Simultaneously, we quantified forage fish abundance and distribution using hydro-acou
The amyloid β-protein (Aβ) is believed to play a central role in Alzheimer’s disease (AD) pathogenesis and there is great interest in understanding the process of Aβ aggregation, its underlying mechanism and the species generated during aggregation and their biological activity. Although Aβ has been studied for more than 30 years, analysis of its aggregation has been hampered by structural and che
BACKGROUND: There is a lack of information on positive work factors among health care workers. OBJECTIVE: To explore salutogenic work-related factors among primary health care employees. METHOD: Questionnaire to all employees (n = 599) from different professions in public and private primary health care centers in one health care district in Sweden. The questionnaire, which had a salutogenic persp
PROBLEM: The Pacific region has widely dispersed populations, limited financial and human resources and a high burden of disease. There is an urgent need to improve the availability, reliability and timeliness of useable health data.CONTEXT: The purpose of this paper is to share lessons learnt from a three-year pilot field epidemiology training programme that was designed to respond to these Pacif
An area and power efficient high-throughput VLSI implementation of a 4 × 4, 64-QAM soft multiple-input-multiple-output (MIMO) detector, that is suitable for high-order constellation schemes is presented. The proposed MIMO detector utilizes information contained in the discarded paths to improve the bit-error-rate (BER) performance, and then reduces computational complexity using three innovative i
Historisk översikt över traditionen med kransflickor vid Lunds universitet med särskilt fokus på de första kransflickorna vid promotionen 1811.
This paper examines organisational responses to eyewitness footage as a mediator in crisis communication. Eyewitness photographs and films is a growing genre of visuals that are difficult for organisations to respond to, because they are regarded as more authentic and true than other images of crisis events. In addition, it is here argued that widely circulated eyewitness imagery often involve ico
Recent advances in real-time magnetic resonance imaging (RT-MRI) have made it possible to study the anatomy and dynamic motion of the vocal tract during speech production with great detail. The abundance of rich data on speech articulation provided by medical imaging techniques affords new opportunities for speech science, linguistics, clinical and technological research and application developmen
