This paper sheds light on the policy coordination concept and explores its implications for science, technology, and innovation (STI) policies at the regional level. In particular it analyzes whether systemic and complex STI policies entail a larger and more complex need for coordination. We contribute to the literature by developing a conceptual framework that brings together insights from instit

Gluco-incretin hormones increase the glucose competence of pancreatic beta-cells by incompletely characterized mechanisms.

In wave propagation problems thin structures are often replaced by boundaries of zero thickness, in order to reduce the numerical mesh. The reduction of thickness has to be incorporated in the approximate boundary condition applied to the interface. This paper presents a modification of an approximate boundary condition originally introduced by Mitzner. The modified Mitzner condition can be applie

We begin by reviewing a classical result on the algebraic dependence of commuting elements in the Weyl algebra. We proceed by describing generalizations of this result to various classes of Ore extensions, including both results that are already known and one new result.

Mate choice for major histocompatibility complex (MHC) compatibility has been found in several taxa, although rarely in birds. MHC is a crucial component in adaptive immunity and by choosing an MHC-dissimilar partner, heterozygosity and potentially broad pathogen resistance is maximized in the offspring. The MHC genotype influences odour cues and preferences in mammals and fish and hence olfactory

Background: Although diet has long been suspected as an etiological factor for colorectal cancer, studies of single foods and nutrients have provided inconsistent results. Objective: We used factor analysis methods to study associations between dietary patterns and colorectal cancer in middle-aged Americans. Design: Diet was assessed among 293 615 men and 198 767 women in the National Institutes o

Data on frequency, severity and correlations of NMS with motor complications are only available for a limited number of NMS. The NMS Scale (NMSS) is a validated tool to assess a broad range of NMS, which has not been used in NMS fluctuations. We assessed fluctuations of a broad range of non-motor symptom (NMS) for a 1-month time period in fluctuating Parkinson's disease (PD) in a multicenter cross

Knowing the genetic variation that occurs in pathogen populations and how it is distributed across geographical areas is essential to understand parasite epidemiology, local patterns of virulence, and evolution of host-resistance. In addition, it is important to identify populations of pathogens that are evolutionarily independent and thus free' to adapt to hosts and environments. Here, we investi

After a brief introduction to some core questions in the history of the book, such as the relationship between form and content, this article investigates the concept of facsimile and its use, and discusses a range of documents that go by the name of “facsimile”. The prevailing definitions of the term “facsimile” focus on the technical means of reproduction and the “exactness” of the copy. However

Kommenterad och med omfattande inledning försedd faksimilutgåva av lundakarnevalspublikationen "Lund just nu!", författad av bl a Axel Wallengren.

A continuous-review two-echelon inventory system with one central warehouse and a number of nonidentical retailers is considered. The retailers face independent Poisson demand and apply standard (R, Q) policies. The retailer order quantities are fixed integer multiples of a certain batch size, representing the smallest pallet or container size transported in the system. A warehouse order may consi

The Universal Thermal Climate Index (UTCI) aimed for a one-dimensional quantity adequately reflecting the human physiological reaction to the multi-dimensionally defined actual outdoor thermal environment. The human reaction was simulated by the UTCI-Fiala multi-node model of human thermoregulation, which was integrated with an adaptive clothing model. Following the concept of an equivalent temper

Akademisk teori såväl som politiska diskussioner framhåller ofta entreprenörskap som gynnsamt för ekonomisk tillväxt. De specifika teoretiska mekanismerna som gör att entreprenörskap leder till tillväxt har dock inte kunnat fastslås och det är därför inte klart om entreprenörskap alltid är ekonomiskt gynnsamt, och för vem? I denna artikel kommer vi att sammanfatta den empiriska forskningen inom en

Background: B-vitamins are essential for one-carbon metabolism and have been linked to colorectal cancer. Although associations with folate have frequently been studied, studies on other plasma vitamins B2, B6, and B12 and colorectal cancer are scarce or inconclusive. Methods: We carried out a nested case-control study within the European Prospective Investigation into Cancer and Nutrition, includ

Background: The Patient Enablement Instrument (PEI), which has been used to evaluate core ingredients in primary care consultations, has been proposed as a means of moving beyond patient satisfaction evaluations. The aim of the present study was to examine the reliability and applicability of the PEI to the Swedish context. Methods: The original PEI was translated to Swedish and included in a ques