In 1553-1554, one Pieter Bruegel retired to Sint-Janshuis, Bergen op Zoom: a home where former servants of the Marquises of Bergen could spend their old age. The main argument of the article is that this retiree, who was the former barber-surgeon of Marquis Jan IV (1541-1567), should be considered as the father of the painter Pieter Bruegel the Elder. The latter’s origins are almost completely unk

Fire evacuation in hospitals is a challenging process that involves the evacuation of patients that are not able to evacuate by themselves and may require assistance. Health-care personnel is generally responsible for assisting the patients during this process. Assisted evacuation in a hospital relies on a pre-determined procedure that defines the priority of patients. The evacuation will depend u

The clinically important MAM blood group antigen is present on haematopoietic cells of all humans except rare MAM-negative individuals. Its molecular basis is unknown. By whole-exome sequencing we identify EMP3, encoding epithelial membrane protein 3 (EMP3), as a candidate gene, then demonstrate inactivating mutations in ten known MAM-negative individuals. We show that EMP3, a purported tumour sup

Conventional road accident risk is measured by the undesirable events/exposure ratio. Common exposure indicators are activity-based, so event-based exposure is needed to achieve event-based safety assessment. Furthermore, road safety simulation is a growing research field. The influence of some software parameters is still unknown. Besides, the use of simulation for exposure assessment is incipien

Identification of biomarkers associated with protection from developing diabetic complications is a prerequisite for an effective prevention and treatment. The aim of the present study was to identify clinical and plasma metabolite markers associated with freedom from vascular complications in people with very long duration of type 1 diabetes (T1D). Individuals with T1D, who despite having longer

Synchrotron radiation (SR) is an interesting tool for probing the properties of the matter in various domains such as nanotechnology, energy materials, catalysis and the cultural heritage. Herein, we synthesized nanomultiferroic samples La1−xCexFeO3 (0.00 ≤ x ≤ 0.15) using auto combustion method and glycine as a fuel. The magnetic behavior was studied and interrelated with the results of synchrotr

The intestine and the brain are connected via the brain-gut axis and the intestinal microbiota influences the immune activation and signaling molecules that are involved in the stress response. The aim of the study was to investigate if intake of the probiotic strain Lactiplantibacillus plantarum HEAL9 (LPHEAL9) for four weeks could counteract elevated cortisol and inflammation levels in subjects

The crystallization rate during selective laser melting (SLM) of bulk metallic glasses (BMG) is a critical factor in maintaining the material's amorphous structure. To increase the understanding of the interplay between the SLM process and the crystallization behavior of BMGs, a numerical model based on the classical nucleation theory has been developed that accounts for the rapid temperature chan

District heating and cooling systems have evolved through several development stages in order to improve their energy efficiency. The latest development reached the fifth generation where customers can be producers and/or consumers of thermal energy flows towards the network. The variety and complexity of system configurations and interactions between connected customers poses a challenge in adopt

Objectives: The primary aim was to find out whether a computer-assisted reading intervention program with a phonic approach can affect event-related (ERPs) and mismatch negativity (MMN) in hearing impaired (HI) children using cochlear implants (CIs). Methods: This study involved a test group of 15 HI children with CIs and a control group of 14 normal hearing (NH) children. The children were 4 year

Phosphor thermometry is a temperature measurement technique that has previously been employed in technically relevant applications to obtain surface temperature. The technique is based on temperature-dependent changes in a phosphor's luminescence. To improve the accuracy and precision of temperature measurements with this technique, the present study considers, by way of example, the impact of con

Strains of microalgae vary in traits between species and populations due to adaptation or stochastic processes. Traits of individual strains may also vary depending on the acclimatization state and external forces, such as abiotic stress. In this study we tested how metal tolerance differs among marine diatoms at three organizational levels: species, populations, and strains. At the species level

Cartridge cases are often the sole items left behind after a shooting incident and DNA traces from these can identify persons connected to the shooting. However, the chance of retrieving usable DNA profiles from cartridge cases is limited, due to the low amounts of deposited DNA and subsequent DNA loss associated with the firing process. In the current study, we set out to increase the DNA recover

We synthesize the current understanding of glacier activity on Svalbard from the end of the Late Pleistocene (12,000 yrs. before present) to the end of the Little Ice Age (c. 1920 AD). Our glacier history is derived from the SVALHOLA database, the first compilation of Holocene geochronology for Svalbard and the surrounding waters, including over 1,800 radiocarbon, terrestrial cosmogenic nuclide an