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Strategies for Enhanced Energy Efficiency and Moisture Management in Brick–AAC Cavity Walls

In Sweden, cavity walls constructed with autoclaved aerated concrete (AAC) inner leaves and clay brick outer leaves were a common design choice during the 1950s to 1970s. These walls often result in relatively extensive heat losses, leading to reduced indoor thermal comfort. Further, moisture-related issues like frost damage and interior dampness are reported for this wall type. This indicates the

Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN

Neuroblastoma (NB) is the most common cancer in infancy with an urgent need for more efficient targeted therapies. The development of novel (combinatorial) treatment strategies relies on extensive explorations of signaling perturbations in neuroblastoma cell lines, using RNA-Seq or other high throughput technologies (e.g. phosphoproteomics). This typically requires dedicated bioinformatics support

Elite para athletes with active coping behaviour are less likely to report a sports injury

Objective Elite para athletes report a high incidence of sports injuries. Research suggests that athletes’ strategies to manage adversities may influence the sports injury risk, but knowledge about para athletes’ coping behaviours and their association with injuries is limited. The aim was to describe the distribution of coping behaviours in Swedish elite para athletes by sex, age, impairment, spo

Dödens pris

Vardagstrycket på UB i Lund innehåller många priskuranter. Här ligger fokus på priser för död och begravning under tidigt 1900-tal. Begravningskostnader motsvarande en månadslön för en arbetare innebar inga extravaganser. En påkostad begravning kunde däremot handla om summor motsvarande flera årslöner för en arbetare.

The Scandinavian Journal of Economics at 125 : a note from the editors

In honor of the 125th year of The Scandinavian Journal of Economics, this paper highlights some of the influential research published here in the last 25 years, considers current trends in the field, and describes a view of the future of this journal in the overall economics research ecosystem.

A large-scale purification of paclitaxel from cell cultures of Taxus chinensis

A large-scale purification method was developed for producing paclitaxel, to guarantee high purity and yield from plant cell cultures. The complete method for mass production was a simple and efficient procedure, for the isolation and purification of paclitaxel from the biomass of Taxus chinensis, consisting of solvent extraction, synthetic adsorbent treatment, and two steps of precipitation, foll

Engineering organs, hopes and hybridity : considerations on the social potentialities of xenotransplantation

The development of replacing human organs with those from genetically modified pigs holds immense potential for alleviating the shortage of organs necessary for patients in need of transplants. This medical advancement is also accompanied by significant social changes, including the emergence of a bioeconomy, new modes of biotechnology governance, altered human-animal relations and increased publi

Unveiling the Mechanisms Behind Temperature-Dependent Impedance Behavior in Polymer Electrolyte Fuel Cells at High Current Loads

Positioning Polymer Electrolyte Fuel Cells (PEFCs) in the market depends on substantial advances that start from a deep knowledge concerning the influence of operating parameters, such as temperature-sweep and high-current density. In the present study, a comprehensive analysis of the impedance behavior of a single PEFC via Electrochemical Impedance Spectroscopy (EIS) was carried out in order to u

An improved high-performance liquid chromatography process for the large-scale production of paclitaxel

The purification of crude (60.89% pure) paclitaxel was developed for high purity and yield. Several solvent systems, including methanol (MeOH), acetone, tetrahydrofurane, n-hexane, and water, were evaluated for precipitation efficiency. The best results were obtained using a mixture of MeOH and water, which was very effective at removing polar impurities, yielding a precipitate with 90.87% purity.

Lipase-catalyzed synthesis of saccharide–fatty acid esters using suspensions of saccharide crystals in solvent-free media

Saccharide–fatty acid esters, important biobased and biodegradable emulsifiers in foods, cosmetics, and pharmaceuticals, were produced with high yields and productivity via immobilized Rhizomucor miehei lipase-catalyzed esterification in solvent-free systems at 65 °C. Preliminary experiments demonstrated high rates of reaction occurred in the presence of acetone near or above its boiling point, du

Exploring the impact of age on the predictive power of the National Early Warning score (NEWS) 2, and long-term prognosis among patients reviewed by a Rapid Response Team : A prospective, multi-centre study

Aim: To explore the impact of age on the discriminative ability of the National Early Warning Score (NEWS) 2 in prediction of unanticipated Intensive Care Unit (ICU) admission, in-hospital cardiac arrest (IHCA) and mortality within 24 hours of Rapid Response Team (RRT) review. Furthermore, to investigate 30- and 90-day mortality, and the discriminative ability of NEWS 2 in prediction of long-term

Association Between the EAT-Lancet Reference Diet and Gestational Diabetes Mellitus : A Mini-Review

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication that seriously endangers maternal and infant health, posing a medical and economic burden worldwide. Several dietary patterns have been recommended for women of childbearing age, demonstrating a positive role in preventing and managing GDM. However, these dietary patterns may not fully take environmental factors into account

Gender-based opportunity structure in the energy sector : a literature review on women’s networking and mentoring

Background: While the energy system is recognized as the largest contributor to climate disruption, the bulk of the sustainability-oriented interventions are made through technologies rather than employment equity and social justice issues. Emergent research points to the critical role of increasing the number of women and other minoritized groups in the energy sector, which could have a cultural,

The Upper Esophageal Sphincter: Anatomy and Physiology

The upper esophageal sphincter (UES), also known as the pharyngoesophageal segment (PES), is a 4-cm segment of the digestive tract that separates the esophagus from the pharynx and larynx. This narrative review represents an overview of the anatomy and physiology of this critical component of the airway protective mechanism. The structure is bounded anteriorly by the larynx, posterolaterally by th

Blood-brain barrier breakdown in brain ischemia : Insights from MRI perfusion imaging

Brain ischemia is a major cause of neurological dysfunction and mortality worldwide. It occurs not only acutely, such as in acute ischemic stroke (AIS), but also in chronic conditions like cerebral small vessel disease (cSVD). Any other conditions resulting in brain hypoperfusion can also lead to ischemia. Ischemic events can cause blood-brain barrier (BBB) disruption and, ultimately, white matter

Is tumour location a dominant risk factor of recurrence in early rectal cancer?

BackgroundImpact of rectal tumour location on risk of lymph node metastases (LNM) and recurrence in early RC is poorly studied and elusive. Tumour location as a prognostic factor may contribute to optimise management of early RC in the future. The aim of this study was to investigate rectal tumour location as an independent predictor of oncologic outcome in early rectal cancer (RC).MethodsRetrospeBACKGROUND: Impact of rectal tumour location on risk of lymph node metastases (LNM) and recurrence in early RC is poorly studied and elusive. Tumour location as a prognostic factor may contribute to optimise management of early RC in the future. The aim of this study was to investigate rectal tumour location as an independent predictor of oncologic outcome in early rectal cancer (RC).METHODS: Retr

A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system

Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete, uns