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Anticipation entails contemplating the beneficial and harmful impacts of scientific and technological progress. Anticipation has a long history in science, technology, and innovation policy partly due to future impacts of scientific progress being inescapable. The link between anticipation, an undertheorized concept, and human rights law is yet to be fully explored. This paper links anticipation t
In an article in this journal, Katherine Drabiak argues that green lighting genome editing of human embryos is contrary to "fundamental human rights law." According to the author, genome editing of human embryos violates what we should recognize as a fundamental human right to inherit a genome without deliberate manipulation. In this reply article, we assess Drabiak's legal analysis and show metho
This article uses empirical investigation of regional hydrogen investments and strategies in Northern Europe to develop a new conceptual approach to regional industrial path development which foregrounds politics and power as explanatory factors in understanding the logics, processes and outcomes of path development. This conceptualisation departs from Evolutionary Economic Geography approaches to
Introduction: Prenatal exposure to inflammatory states has been suggested to influence offspring neurodevelopment. The aim was to investigate if offspring exposure to maternal Inflammatory bowel disorder (IBD), or specifically the IBD disorder Crohn's disease, during gestation is associated with neurodevelopmental or psychiatric disorders in childhood. Material and Methods: We conducted a populati
The Human Right to Science is about the “human right to benefit from progress in science and its applications,” also known more succinctly as the “right to science.” Although the right to science is one of the oldest internationally recognized human rights, it has suffered too long from neglect. International organizations and States pay little attention to it. There are only a few inadequate indi
Advances in quantum computing pose a fundamental threat to classical public-key cryptosystems, including RSA and elliptic-curve cryptography (ECC), which form the foundation for authentication and key exchange in the Transport Layer Security (TLS) protocol. In response to these emerging threats, Korea launched the KpqC (Korea Post-Quantum Cryptography) project in 2021 to design, evaluate, and stan
Background/Objectives: Sepsis is a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection. Mitochondrial dysfunction is considered a key contributor to the pathogenesis of sepsis, but its molecular mechanisms remain unclear. Methods: In this study, we used a cecal ligation and puncture (CLP) model to induce sepsis in wild-type (WT) and cyclop
Introduction: Non-suicidal self-injury (NSSI) is often met with stigma, which can deter individuals from seeking help. While most research on NSSI stigma has focused on clinical settings, the attitudes of those most likely to receive an NSSI disclosure, such as peers, friends, and family, remain underexplored. Building on qualitative findings that positive disclosure experiences can foster support
Proteins and peptides are vital biomolecules, and deuterated amino acids are increasingly applied in areas such as drug discovery, metabolic tracing, and neutron scattering studies. In this study, we performed deuteration on all 20 proteinogenic amino acids, including their side chains, and established efficient methods for 13 amino acids. Using a Pt/C-catalyzed hydrogen–deuterium exchange reactio
People often feel less empathy towards outgroup compared to ingroup targets. Overcoming this intergroup empathy bias is important for fostering positive intergroup relations. In five pre-registered and high-powered online studies (n = 4776 (745/745/1056/1236/994)), we attempted to replicate and generalize motivated empathy interventions that previously have made people more empathetic and prosociaPeople often feel less empathy towards outgroup compared to ingroup targets. Overcoming this intergroup empathy bias is important for fostering positive intergroup relations. In five pre-registered and high-powered online studies (n = 4776 (745/745/1056/1236/994)), we attempted to replicate and generalize motivated empathy interventions that previously have made people more empathetic and prosocia
Background: Large bone defects are challenging to manage clinically and usually require treatment with bone graft or bone graft substitute. This study evaluated the effect of romosozumab, a sclerostin antibody, in combination with demineralized bone matrix (DBM) on bone regeneration in a critical-size ulnar defect model in nonhuman primates. Methods: In cynomolgus monkeys (N = 22, male, 10–12 year
Epithelial tissue fusion requires coordinated molecular events at the ends of two epithelial structures. Regulatory mechanisms controlling these events remain largely elusive. In the Drosophila reproductive system (RS), this fusion unites the gonad and the genital disc-derived tissues, into a continuous tube. This study unveils the pivotal role of Hamlet (Ham), a Drosophila PR domain containing
The premiere of the film National Pride: From Jericho to Gaza (Fierté Nationale: De Jéricho vers Gaza) was held at Visions du Réel in Nyon, Switzerland, April 8, 2025.
In many tasks, participants are instructed to fixate a target. While maintaining fixation, the eyes nonetheless make small fixational eye movements, such as microsaccades and drift. Previous work has examined the effect of fixation point design on fixation stability and the amount and spatial extent of fixational eye movements. However, much of this work used video-based eye trackers, which have i
Background: Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide. Circulating endothelial cells (CECs) have been reported to be involved with the early stages of AMI. The specific objective of our study was to discover early diagnostic markers of CECs in circulation using bioinformatics analysis. Methods: Raw microarray data of the GSE66360 dataset were acquire
The aim of this study was to rank the rate and risk ratio of subject injury following exposure to less-lethal force modalities in real-life police interventions. The purpose was to observe whether the use of conductive electrical weapons (CEW) qualifies as a low-risk modality of force, with a similar risk of adverse health outcomes as exposure to other less-lethal modalities, such as physical forc
Background: The association between different patterns of healthcare use and non-recovery in patients with spinal disorders is unclear. We aimed to assess the association between healthcare use and non-recovery 6 months after a specialist evaluation in Norwegian secondary care and whether non-recovery was linked to adherence to specialist-recommended care. Methods: This observational registry-base
Background: Prolonged time to surgery (TTS) after neoadjuvant chemoradiotherapy (nCRT) may enable malnourished oesophageal cancer patients' nutritional status to recover better, possibly improving outcomes with fewer complications and better overall survival (OS) after oesophagectomy. Methods: This is a substudy within a multicentre randomised controlled trial comparing outcomes in patients with o
