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Evaluation of a Novel Automated Cerebral Ventricular Drainage System for Intracranial Pressure Monitoring and Cerebrospinal Fluid Drainage in Neurocritical Care Patients : A Prospective, Randomized Clinical Study

BACKGROUND: Neurointensive care is moving toward more automated patient management. This study aimed to evaluate a novel external ventricular drainage (EVD) system, the VGuard® system, as a tool for intracranial pressure (ICP) monitoring and automating ventricular drainage of cerebrospinal fluid (CSF), focusing on its safety and potential to reduce complications associated with manual EVD manageme

Blink parameters are confounded by vertical eye orientation in video-based eye tracking : Comparing pupil- and eyelid-based methods

Blink characteristics such as duration, amplitude, and eyelid velocity are widely used indicators of cognitive and physiological states. While early magnetic search coil studies suggested that vertical eye orientation relative to the head influences blink measurements, subsequent research has largely ignored this factor. No studies have investigated whether vertical eye orientation effects replica

Engelska influenser i tre frihetstida tragedier

Swedish tragedies from the first half of the eighteenth century often looked at French drama, but there are notable instances where inspiration seems to have come from elsewhere: Erik Wrangel’s Torilla (1738), for example, breaks conventions expected of French theatre by letting princes battle supernatural forces on stage; the story presented in Eric Brander’s Cleopatra (1749) seems familiar from

Carbonated ultramafic igneous rocks in Jezero crater, Mars

The Perseverance rover landed in Jezero crater on Mars, which once contained a lake of liquid water. We report the rock properties encountered by Perseverance during a 10-kilometer traverse extending over 400 meters in elevation, from beneath Jezero's western sedimentary fan to the upper crater rim. These rocks consist of coarse-grained olivine, magnesium and iron carbonates, silica, and phyllosil

Alcohol consumption in metabolic dysfunction-associated steatotic liver disease (MASLD) : understanding the gut–liver crosstalk for clinical translation

Objective: In the present study, we investigated the role of the gut–liver crosstalk in the pathogenesis of steatotic liver disease (SLD) induced by the compounding and deleterious effects of alcohol and metabolic risk factors, and explored the potential translational aspects of microbiome-based interventions. Design: The effects of combined exposure to alcohol and a high-fat, high-cholesterol die

Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease

The link between regional tau load and clinical manifestation of Alzheimer's disease (AD) highlights the importance of characterizing spatial tau distribution across disease variants. In typical (memory-predominant) AD, the spatial progression of tau pathology mirrors the functional connections from temporal lobe epicentres. However, given the limited spatial heterogeneity of tau in typical AD, at

Icke-produktivitet och svaga tankar : en feministisk genealogi från 1970-talets Sverige

In Swedish feminist debates of the 1960s and 1970s, the productive woman was frequently constructed as the binary opposite of the non-productive woman. The former was associated with liberation, moral integrity, and independence. The latter was characterized in terms of passivity, laziness, and dependence. By engaging in paid labour, or by otherwise demonstrating her contribution to the greater go

Mild hyperventilation with preserved exercise capacity in patients with self-reported long-term dyspnea after COVID-19-a prospective cohort study in a primary healthcare setting

BACKGROUND: Post COVID-19 condition remains a complex and challenging issue, with diverse manifestations, despite accumulating research and clinical experience. Dyspnea is one of the most common symptoms reported in post COVID-19 condition. Cardiopulmonary exercise testing (CPET) offers a cohesive assessment of dyspnea and exercise limitations. The Nijmegen questionnaire is a form for assessment o