Filtyp
Landskronas öppna verkstad undersöker hur ett mindre tillägg i en urban kontext kan bidra till en ökad aktivering av närområdet och samtidigt ge utrymme för ökad rörelse från resten av staden. Projektet tar sin utgångspunkt i ambitionen att skapa ett genomarbetat förslag som förhåller sig till de funktionella krav som ställs, samtidigt som det är starkt förankrat i sin kontext. Projektet prövar id
Papain-like protease (PLpro) of SARS-CoV-2 is a vital enzyme involved in viral polyprotein processing and in the suppression of host immune response. Due to its strategic role in viral replication and pathogenesis, PLpro represents a valid yet challenging target for drug development. Fragment-based drug discovery (FBDD) is a powerful strategy employed by the FragMAX facility at MAX IV to identify
Alzheimer's disease (AD) is a neurodegenerative disease that often occurs in the elderly and is often accompanied by cognitive loss. Its main pathological features are the formation of amyloid-beta (Aβ) plaques and Tau tangles in the brain. Here, we used single-cell RNA sequencing (scRNA-seq) combined with computational cell–cell communication (CCC) analysis to systematically investigate trans
Consistent behavioural differences among individuals can have significant ecological and evolutionary consequences, yet their origins and persistence within populations have proven challenging to determine. In newly established populations at expanding range margins, behavioural variation may result from natural selection and spatial sorting, with behavioural types that promote dispersal being mor
Sexually reproducing species tend to have reproductive barriers between them that prevent hybrid offspring from being formed. Drosophila melanogaster and D. simulans are two closely related species that can form sterile hybrids. In addition to their post-zygotic barriers, which cause the hybrid sterility, some behavioral pre-zygotic barriers also exist. These include different preferences for cour
When cultivating barley (Hordeum vulgare), access to cultivars with shorter flowering time can be helpful in various agricultural settings, such as the effort of expanding agricultural capabilities into colder regions with shorter growing seasons. The recently identified gene Praematurum-b (Mat-b) is known to cause the plants to flower 7 days early on average. This thesis aimed to analyze the effe
Due to human-induced environmental changes, many natural populations are undergoing extensive fitness declines. Natural or sexual selection could potentially shift the phenotypic mean of critical traits towards new phenotypic optima, promoting evolutionary rescue. However, this process has rarely been studied in natural populations. Furthermore, the population fitness can also be increased by gene
The extensive use of pesticides within the agricultural landscape is essential for maintaining sufficient yields and sustaining our growing population, however, their widespread use is not without costs. Increasing evidence shows that pesticides harm many non-target organisms, including those providing vital ecosystem services. Pollinators, for instance, are critical for the fruiting of nearly 75%
Path integration is a navigational strategy that allows animals to return home in a straight line after an outbound journey, by integrating the distance and direction traveled. With their accessible brains, insects are the perfect model organisms to study this target-directed behavior at the neural level. The Central Complex (CX) is a group of neural structures (neuropils) in the insect brain suit
Bakgrund: Digital kommunikation som chatt blir allt vanligare i dagens primärvård. Kontakt via chatt ställer särskilda krav på distriktssköterskans arbetssätt. Studien utgår från Travelbees human-to-human-relationsteori, där empati, sympati och kommunikation är centrala för meningsfulla vårdrelationer Syfte: Syftet var att undersöka distriktssköterskors upplevelser och erfarenheter av bedömningar
The Iberian lynx was once recognized as the world’s most threatened felid, but due to the implementation of a conservation programme and the creation of captive breeding centres, its numbers have considerably increased. With the annual production of new individuals in these reproduction centres, as well as the inevitable aging of past breeders, a different problem emerged: the hoarding of non-repr
The spread of multiuse landscape worldwide has drastically increased humanwildlife interactions and especially negative impacts of wildlife on human assets. Human-wildlife interactions threaten both biodiversity conservation and farmers’ livelihood, especially in low-income areas where farming practices are their main source of income. In Zimbabwe, wildlife damage to crops and livestock creates te
This study investigates code-switching by Swedish English speakers in text-based online discourse. Although many studies have been devoted to CS and some to text-based online discourse, there is a gap in research regarding Swedish English CS in this context. This study fills the gap using comments from Swedish YouTube short-form videos, which were placed into 6 categories based on what the switch
This thesis explores the potential and limitations of basalt fibre textile in the context of products within the commercial market. Due to its heat insulation capabilities, combined with its fire resistance, durability and eco-friendliness, basalt fibre is currently mostly utilized in construction. Hence, the material itself is rarely visible to the user, but hidden behind drywalls or buried in co
Bakgrund: Beslut om livsuppehållande åtgärder (LUÅ) inom akutsjukvård utgör en komplex del av sjuksköterskans yrkesutövning och innebär ofta etiska och emotionella utmaningar. Utförandet av livsuppehållande åtgärder kan medföra att förlängt liv, ibland på bekostnad av en försämrad livskvalitet för patienten. Den akuta och tidskritiska vårdmiljön medför risk för att patientens autonomi, delaktighetBackground: Decisions regarding life-sustaining treatment (LUÅ) in emergency care represent a complex aspect of nursing practice and often involve ethical and emotional challenges. The implementation of life-sustaining treatment can prolong life, sometimes at the expense of the patient’s quality of afterlife. The acute and time-critical care environment entails a risk that the patient’s autonomy,
The desire for a deeper connection with nature has become increasingly apparent. The shift towards eco-conscious living, as demonstrated by the popularity of gorpcore and the nomad lifestyle, shows that people want to make more sustainable and nature-inspired choices. In response to this cultural shift, I am motivated to channel these environmental sentiments into a design project — the creation
Bakgrund: Akutsjukvården präglas av hög arbetsbelastning, tidsbrist och begränsade resurser, vilket skapade en spänd arbetsmiljö för sjuksköterskor. Krav-Kontroll-stödmodellen beskriver hur kombinationen av arbetskrav, kontroll och socialt stöd påverkar balans eller obalans, medan coping och resiliens är återhämtningsförmågor som påverkar sjuksköterskan att hantera påfrestningar. Syfte: SjuksköteBackground: Emergency care is characterized by high workload, time constraints, and limited resources, which create a tense work environment for nurses. The Job Demand–Control–Support model describes how the combination of job demands, control, and social support affects balance or imbalance, while coping and resilience are recovery abilities that influence the nurse’s capacity to handle stressors
Över hela världen ingick sjuksköterskor i en första linjen-strid mot viruset SARS CoV-2 som ledde till att COVID-19-pandemin förklarades i mars 2020 (WHO, 2020). Akutmottagningen fungerar som en första instans för de flesta patienter som passerar in till sjukhus vid akut sjukdom vilket ledde till att stora förändringar behövde genomföras på kort tid i form av utökade isoleringsplatser, organise
