This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils. C57BL/6 wild-type (WT) and AnxA1 knockout mice (AnxA1-/-) received 0.3% carrageenan intraperitoneally and, after 3 h, the peritoneal exudate was collected. WT and AnxA1-/- neutrophils were then stimulated with lipopolysaccharide, followed by t

In memorium commentary about the Romanian anthropologist Vintila Mihailescu, who died in 2020, published as part of several contributions in Anuac, the journal of the Italian Society for Cultural Anthropology

Annexin A1 (AnxA1) is an anti-inflammatory protein expressed in various cell types, especially macrophages and neutrophils. Because neutrophils play important roles in infections and inflammatory processes and the relationship between AnxA1 and Candida spp. infections is not well-understood, our study examined whether AnxA1 can serve as a target protein for the regulation of the immune response du

OBJECTIVE: To identify clinical, microscopic, and biochemical characteristics that differentiate cytolytic vaginosis (CV) from vulvovaginal candidiasis (VVC).METHODS: The present cross-sectional study analyzed the vaginal contents of 24 non-pregnant women aged 18 to 42 years who were attended at the Genital Infections Clinic at Centro de Atenção Integral à Saúde da Mulher da Universidade Estadual

Annexin A1 (AnxA1) is a potent anti-inflammatory protein that downregulates proinflammatory cytokine release. This study evaluated the role of AnxA1 in the regulation of NLRP3 inflammasome activation and lipid release by starch-elicited murine peritoneal macrophages. C57bl/6 wild-type (WT) and AnxA1-null (AnxA1-/-) mice received an intraperitoneal injection of 1.5% starch solution for macrophage r

OBJECTIVE: To evaluate endocervical and vaginal environment changes in women using a levonorgestrel-releasing intrauterine system (LNG-IUS).METHODS: A quasi-experimental study included sixty women who had an LNG-IUS inserted in the Family Planning Clinic of UNICAMP between April and November of 2016. Women in reproductive age, non-pregnant, without the use of antibiotics and contraceptives seeking

INTRODUCTION: Genital hygiene can play an essential role in avoiding vulvovaginal discomfort and preventing infections. The scientific evidence on best practices on genital hygiene is scarce, and without doubt, gynecologists should be the best person to discuss and guide the subject.OBJECTIVE: Evaluate the general genital female gynecologist hygiene.METHODS: This descriptive analytic study identif

OBJECTIVE: To characterize the lipid profile in vaginal discharge of women with vulvovaginal candidiasis, cytolytic vaginosis, or no vaginal infection or dysbiosis.DESIGN: Cross-sectional study.SETTING: Genital Infections Ambulatory, Department of Tocogynecology, University of Campinas, Campinas, São Paulo-Brazil.SAMPLE: Twenty-four women were included in this study: eight with vulvovaginal candid

The aims of this study was to review the practical of the immediate vaginal diagnosis by Gram staining in the gynecological practice. The elucidation and characterization of the vaginal microorganisms is important for providing a better understanding of the women’s health and diseases, as well as the search for adequate diagnosis and treatment. Here we described the processes about the approaches

This paper examines the complementarity between the market for electric vehicles and fast charging on the Swedish market from the introduction of these technologies on the market until the third quarter 2015. Three ecosystems are identified based on the standards Chademo, CCS and the Tesla proprietary charging technology. The analysis points to the need for studying markets for electric vehicles a

Protoplanetary disks are the natural by-product of star formation and the sites of planet formation. Initially, they are composed of the gas and small solids they inherit from the molecular cloud they form in. The interactions between this material is complex and understanding their details is key for a complete picture of planet formation. The planet formation process begins with growth form abou

För att beskriva lagarna som styr den fysiska världen, behöver vi studera materiens struktur och hur dess olika delar växelverkar. Den grundläggande byggstenen för all känd materia i universum är atomen, vilken består av elektroner som rör sig runt en atomkärna. Atomen är ett kvantiserat mångkropparsystem, vars struktur karakteriseras av de diskreta och för ämnet unika energinivåer. Växelverkan meThis thesis deals with the relativistic modeling of atoms and ions. To interpret the stellar spectra and gain more insight from astrophysical observations, the underlying processes that generate the spectra need to be well understood and described. Examples of such processes are the interactions of atomic electrons with internal and external electromagnetic fields and with the nucleus.By exploring

This paper investigates the structural political economic drivers of the housing market in urban Iran and the ways in which social and economic dynamics of the housing sector are rooted in peculiarities of Iranian capitalism, characterized by a relatively small public economy, low productivity of capital, and an underdeveloped financial system. The paper examines these processes and mechanisms in

Society’s planning for and dependence on automobility has created several major problems and calls for a shift away from car-based mobility are proliferating. There is a growing recognition of the positive effects of cycling and modal shares for cycling are on the rise in cities. Nevertheless, bicycling is still marginalised in national transport policies. In Sweden, cycling shares are decreasing

Formalized triage has been implemented in all Danish emergency departments. The validation behind formalized triage has focused on investigating predictive validity, i.e. correspondence between triage category and different outcome measures. Reliability is primarily investigated in terms of inter-rater reliability on written patient cases, and several studies have methodological limitations questi

Background The prognostic value of blood lactate as a predictor of adverse outcome in the acutely ill patient is unclear. The aim of this study was to investigate if a peripheral venous lactate measurement, taken at admission, is associated with in-hospital mortality in acutely ill patients with all diagnosis. Furthermore, we wanted to investigate if the test improves a triage model in terms of pr