Amyloid fibrillering, en process där peptider (små protein) klumpas ihop, är idag associerat med en rad sjukdomar såsom Alzheimers sjukdom och diabetes typ 2. En peptid som är associerad med diabetes typ 2 är IAPP. Peptiden har hittats fibrillerad i bukspottskörteln i många patienter med diabetes typ 2. I tidigare studier har det hittats en koppling mellan små plaster, så kallade nanoplaster, och The impact of nanoparticles on amyloid fibrillation has been studied for some time due to the amount of nanoparticles that can be found in nature due to human release. Previous studies have shown that different nanoparticles may affect the length of the lag phase of the fibrillation process. This has been studied on peptides such as amyloid beta and islet amyloid polypeptide. Research has shown th

Médecins Sans Frontières (MSF) does currently not have dedicated decision-making support for their in-country inventory allocation and is exploring how such decision support framework could be designed to enhance their supply chain operations. The purpose of this thesis is thus to develop a structured framework for country-level inventory allocation decision-making at MSF.To fulfil the purpose t

This thesis explores the configurability of IPs for ASICs by looking into the design of SPI_S, an IP used for communication between ASICs and peripheral devices. Configurability is explored to reduce manual labor when requirements set on the IP change between projects. The thesis looks into the challenges of developing a configurable IP, including architecture, design, and verification. In additio

Music’s diverse psychological roles include possible cognitive enhancement, however, results are either insufficient or mixed based on already existing literature. The current interventional study observed the influence of musical stimuli on time perception and sustained attention possibly explained by altered states of consciousness. 30 participants were assigned equally to two different musical

Surgical treatment of liver metastases from colorectal cancer (CLM) is the only treatment option with curative potential; however, only about 15% to 20% of the patients seen at major hospitals are candidates for surgical resection. In a prospective study of liver transplantation (Ltx) for non-resectable CLM a 5-year overall survival rate of 60 % has been shown. We now plan to evaluate if the addit

Colored sticky traps are used for management of many common agricultural insect pests. Several recent studies have shown that traps can be improved by systematically considering properties of color vision for the target species. In the current study, we extend this approach to spatial vision, using information about the interommatidial angle of an agriculturally important insect pest, western flow

Background: Corticosteroids appears to be beneficial for severe Mycoplasma pneumoniae pneumonia in children, but data in adults are limited. This study investigated effects of adjunctive corticosteroids in hypoxemic adults with M. pneumoniae pneumonia. Methods: Adults admitted 2013-2017 with verified M. pneumoniae pneumonia and hypoxemia (SpO2 < 93% or oxygen treatment) were included in a cohort.

We report the discovery and characterization of two sub-Saturns from the Transiting Exoplanet Survey Satellite (TESS) using high- resolution spectroscopic observations from the MaHPS spectrograph at the Wendelstein Observatory and the SOPHIE spectrograph at the Haute-Provence Observatory. Combining photometry from TESS, KeplerCam, LCOGT, and MuSCAT2, along with the radial velocity measurements fro

Inspired by the workshop "Sacred Canopies: LGBT+, Buddhism, and Economics in Vietnam,"hosted at the University of Copenhagen in November 2023, this introduction frames the themes of the special issue. It focuses on how Vietnam's globalized market economy is shaping LGBTQI+ aspirations, mobilizations, personhoods, and spiritual experiences. It explores how the articles in this special issue shed ne

Denna studie ämnar att redogöra potentialen för energigemenskaper i Näsby, Kristianstad. Detta utreds i arbetet genom att undersöka om lokalnätet kan avlastas, samt om elnätskunderna kan erhålla kostnadsbesparingar. Rapporten är ett examensarbete för en civilingenjörsexamen i maskinteknik på Lunds Tekniska Högskola, och utförs tillsammans med C4 Energi AB. Studien omfattar en litteraturstudie som The aim of this study is to examine the potential of energy communities in Näsby, Kristianstad, and more specifically the values they may provide the involved parties. This report is a Master’s thesis written at Lunds Tekniska Högskola, in collaboration with C4 Energi AB. The study involves a literature study with the purpose of determining in what form an energy community could be constructed in

Proteomic analysis can reveal substantial information about cells and cell types, including biomarkers that can be used to distinguish subpopulations. Established protocols include manual pipetting steps of cells that are both time consuming and problematic in terms of samples losses. In this study, a new “FACS-into-evotip” protocol for proteomic analysis was evaluated with the goal to automate sa

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, characterized by an aggressive progression. Emerging evidence suggests that the tumor immune microenvironment (TIME), particularly tumor-infiltrating T cells, plays a key role in disease progression and prognosis for patients that are treated with modern combined immunotherapeutic regiments. Thus, the develop

Quantum entanglement is a fundamental resource for various quantum information applications including quantum computing, cryptography, and teleportation. However, detecting entanglement in practice can be challenging due to noisy measurements and limited control over the systems being studied. Steering, which is a distinct nonlocal property between entanglement and bell nonlocality (the strongest

Amid a global housing crisis that leaves more than 1.6 billion people inadequately housed, dominant legal and policy frameworks still define “adequate housing” largely in terms of fixed outcomes such as tenure security, affordability, and habitability. This thesis argues that these lists overlook a critical dimension: people’s housing agency, the real freedom to shape their housing situation. Grou