Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to the guidelines is lacking. The guidelines were developed to avoid unnecessary suffering from preventable conditions. The aims of the study were to investigate 1) planned health care visits in relation to the co-morbidities described in specific medical guideline

https://www.lupop.lu.se/article/health-care-utilisation-among-older-people-down-syndrome-compared-specific-medical-guidelines-health - 2025-09-03

Cluster analyses were performed to group variables with close proximity and to obtain homogenous clusters of individuals (n = 22,057) in the Malmö Preventive Project (MPP) cohort. Variables clustered included obesity, kidney dysfunction, diabetes mellitus (DM), hypertension, cardiovascular disease (CVD), dyslipidemia, pulmonary dysfunction (PD), smoking, and the use of diuretics. Incidence rates a

https://www.lupop.lu.se/article/absolute-risk-gout-clusters-gout-associated-comorbidities-and-lifestyle-factors-30-years-follow - 2025-09-03

Maldescended testes or cryptorchidism is a genital birth defect that affects 2–9% of all male new-borns. Over the last 40 years there have been reports of increased prevalence in countries like the US, the UK and the Scandinavian countries. This possible increase has in some studies been linked to a foetal exposure to chemical pollutants. In this matched casecontrol study, we analysed maternal ser

https://www.lupop.lu.se/article/exposure-polychlorinated-compounds-and-cryptorchidism-nested-case-control-study - 2025-09-03

COVID-19 and lockdown strategies may affect mental health and addictive behavior differently in the population, and elite athletes are among the professions clearly affected by the pandemic. This study in top elite athletes aimed to study current perceived psychological influence from COVID-19 and symptoms of depression, anxiety and changes in alcohol drinking, gambling behavior and problem gambli

https://www.lupop.lu.se/article/psychological-distress-and-problem-gambling-elite-athletes-during-covid-19-restrictions-web-survey - 2025-09-03

Maldescended testes or cryptorchidism is a genital birth defect that affects 2–9% of all male new-borns. Over the last 40 years there have been reports of increased prevalence in countries like the US, the UK and the Scandinavian countries. This possible increase has in some studies been linked to a foetal exposure to chemical pollutants. In this matched casecontrol study, we analysed maternal ser

https://www.lupop.lu.se/article/exposure-polychlorinated-compounds-and-cryptorchidism-nested-case-control-study-0 - 2025-09-03

The obesity epidemic has influenced pain rehabilitation clinics. To date, little is known about baseline level of physical activity (PA) in patients referred to pain rehabilitation clinics. We aimed to investigate the PA levels of patients referred to pain rehabilitation clinics and to evaluate the effect of excess weight on PA level. Read more at Facing obesity in pain rehabilitation clinics: Pro

https://www.lupop.lu.se/article/facing-obesity-pain-rehabilitation-clinics-profiles-physical-activity-patients-chronic-pain-and - 2025-09-03

Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients. Read more at Familial asso

https://www.lupop.lu.se/article/familial-associations-between-autoimmune-hepatitis-and-primary-biliary-cholangitis-and-other - 2025-09-03

The study population included a random sample of 2656 men (45.7%) and 3159 (54.3%) women from the longitudinal national studies' "Good Aging in Skåne" (GÅS) and SNAC-B, both part of the Swedish National Study on Aging and Care (SNAC). Data on Neugartens Life Satisfaction Index-A (LSI-A), medical history, activities of daily life (ADL) and socio-demographics were collected through structured interv

https://www.lupop.lu.se/article/life-satisfaction-index-lsi-normative-data-general-swedish-population-aged-60-93-years - 2025-09-03

Öppna utlysningar: Bidrag till kliniska studier inom behandlingsforskning - skissansökan / Bidrag till investering i befintlig forskningsinfrastruktur / Internationell postdok inom medicin och hälsa (vårens utlysning) / Internationell postdok inom naturvetenskap och teknikvetenskap (vårens utlysning) / Internationell postdok inom humaniora och samhällsvetenskap inklusive utbildningsvetenskap (våre

https://www.lupop.lu.se/article/vrs-utlysningsar-2021-ar-nu-igang - 2025-09-03

It is now much easier for researchers to make use of SND’s web services. The first step is an improved service for the submission of research data for description and reuse. The next step will simplify the process of ordering data from SND. Read more here.

https://www.lupop.lu.se/article/snd-launches-improved-web-service-researchers - 2025-09-03

Att forskningsresultat ska kunna upprepas är en av vetenskapens grundläggande principer. Ändå visar flera genomgångar av vetenskapliga studier att det inte ser ut så. Kritiker pekar på flera orsaker och nu vill forskare minska fokus på publiceringshetsen för att minska felaktigheter. Hör mer på https://sverigesradio.se/artikel/7647634.

https://www.lupop.lu.se/article/problem-i-forskarvarlden-manga-forskningsresultat-kan-inte-upprepas - 2025-09-03

Traumatic brain injury (TBI) is a major cause of disabilities and mortality worldwide, with higher prevalence in offender populations than in the general population. Previous research has strongly advocated increased awareness of TBI in offender populations. The aim of this study was to explore the prevalence and characteristics of TBI, and to investigate associations and interactions between TBI,

https://www.lupop.lu.se/article/exploring-traumatic-brain-injuries-and-aggressive-antisocial-behaviors-young-male-violent-offenders - 2025-09-03

The Kingdom of Crystal, an area in southern Sweden famous for its many glassworks, is historically heavily burdened by pollution from this industry. Glass crust containing cadmium (Cd), lead (Pb), and arsenic (As) has been deposited around the area and used as filling. The purpose of this study was to monitor whether the high levels of metals in the contaminated soil were reflected in blood and ur

https://www.lupop.lu.se/article/cadmium-and-lead-levels-blood-and-arsenic-levels-urine-among-schoolchildren-living-contaminated - 2025-09-03

It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level of circulating inflammatory proteins and that chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how added sugar and SSB intake associate with 136 measured plasma proteins and C-reactive protein (CRP) in the Malmö Diet and Cancer–Cardiovascular Cohort

https://www.lupop.lu.se/article/identification-inflammatory-and-disease-associated-plasma-proteins-associate-intake-added-sugar-and - 2025-09-03

With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [granulomatosis with polyangiitis (GPA), microscopic polyangiitis, and eosinophilic GPA] diagnosed between 1997 and 2010 were assessed. The patients were followed until death or December 31, 2015. The age- and sex-standardized incidence ratios (SIR) were estimated using the Swedish population data

https://www.lupop.lu.se/article/malignancies-patients-antineutrophil-cytoplasmic-antibody-associated-vasculitis-population-based - 2025-09-03

Data were obtained from the prospective, longitudinal, population‐based Children of Western Sweden cohort, which focused on children born in 2003. The parents answered questionnaires at six months and one, four, eight and 12 years of age. Personal identity numbers linked 3634 children to the Swedish Prescribed Drug Register (SPDR) and the National Patient Register (NPR). Read more at Parental ques

https://www.lupop.lu.se/article/parental-questionnaires-provided-reliable-data-childhood-asthma-compared-national-registers - 2025-09-03

Quality in medical research has recently been criticized for being low, especially in observational research. Methodology is increasingly difficult, but collaboration between clinical researchers and biostatisticians may improve research and reporting quality. The aim of this study is to quantify the value of a biostatistician in the team of authors. Read more at Is reporting quality in medical pu

https://www.lupop.lu.se/article/reporting-quality-medical-publications-associated-biostatisticians-co-authors-registered-report - 2025-09-03

This study extends TCAL by disentangling causes of death contributions. The strength of the approach is that it allows identification of mortality differences in cohorts with members still alive, as well as identification of which ages and causes of death contribute to mortality differentials between populations. Read the paper at https://academic.oup.com/ije/article/49/5/1712/5721433

https://www.lupop.lu.se/article/reflection-modern-methods-cause-death-decomposition-cohort-survival-comparisons - 2025-09-03

Advances in synthetic control methods bring new opportunities to conduct rigorous research in evaluating public health interventions. However, incorporating synthetic controls in interrupted time series studies may not always nullify important threats to validity nor improve causal inference. Read the paper at https://academic.oup.com/ije/article/49/6/2010/5917161

https://www.lupop.lu.se/article/can-synthetic-controls-improve-causal-inference-interrupted-time-series-evaluations-public-health - 2025-09-03

Concerns have been expressed over standards of statistical interpretation. Results with P <0.05 are often referred to as ‘significant’ which, in plain English, implies important. This leads some people directly into the misconception that this provides proof that associations are clinically relevant. Read the paper at https://academic.oup.com/ije/article/49/6/2083/5876177

https://www.lupop.lu.se/article/reflection-modern-methods-statistics-education-beyond-significance-novel-plain-english - 2025-09-03