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Dr. Olle Lindvall, recently awarded a jubilee doctorate from Lund University, has spent more than fifty years studying the brain and how to repair it. His work has turned ideas that once seemed like science fiction into scientific reality. Looking back on his journey from curious medical student to clinical neuroscientist, he talks about his accomplishments, the challenges he faced, and gives advi

https://www.stemcellcenter.lu.se/article/what-fuels-lifetime-scientific-discovery-olle-lindvall-reflects-his-journey-neuroscience - 2025-12-15

Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune system fight cancer. Their approach, now published in the journal Science, could lead to more effective treatments for hard-to-treat cancers. Cancer is known for its ability to hide from the immune system, making it tough to fight. But what

https://www.stemcellcenter.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-12-15

By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for researchers, and it was held in front of an audience of almost 400 students at Helsingborg's Stadsteater on 1 October. His presentat

https://www.stemcellcenter.lu.se/article/research-reprogramming-cancer-cells-won-presentation-competition-research-grand-prix - 2025-12-15

Olga Zimmermannova from the Pereira Research Group has been awarded the 2024 Article of the Year Award. She received the award for her research on reprogramming cancer cells into dendritic cells of the immune system as a potential cancer therapy. The Lund Stem Cell Center Article of the Year Award, presented annually since 2017, highlights exceptional research conducted at the Center that contribu

https://www.stemcellcenter.lu.se/article/lund-stem-cell-centers-2024-article-year-goes-olga-zimmermannova - 2025-12-15

Two researchers at Lund Stem Cell Center receive grants, 61 million, for research into immunological long-term memory and reprogramming of tumor cells. The research should lead to more effective vaccination strategies and immunotherapies. The Knut and Alice Wallenberg Foundation has granted SEK 835 million to 30 different projects in medicine, natural science and technology that are deemed to have

https://www.stemcellcenter.lu.se/article/yuan-and-pereira-receive-grants-wallenberg-foundation - 2025-12-15

Joan Yuan, researcher and associate professor in immunology, receives the Eric K. Fernström prize for younger, particularly promising and successful researchers at Lund University in 2024. Her research is about how the immune system is formed and how it affects us throughout life. Award justification: "For her decisive discoveries that have changed our understanding of hematopoiesis and the immune

https://www.stemcellcenter.lu.se/article/eric-k-fernstrom-award-young-successful-researchers-goes-joan-yuan - 2025-12-15

Researchers at Lund University’s Lund Stem Cell Center have made a new discovery about how the human genome protects itself from disruption during critical stages of life. Their study, recently published in Nature Communications, reveals how two key defense mechanisms—DNA methylation and the HUSH complex—work together to safeguard genomic stability. The human genome contains large stretches of rep

https://www.stemcellcenter.lu.se/article/new-research-gives-insights-human-genomes-defence-mechanisms - 2025-12-15

Researchers at Lund University’s Lund Stem Cell Center have made new strides in understanding why some patients with chronic myeloid leukemia respond better to treatment than others. Their study, recently published in eLife, suggests that the amount of healthy blood stem cells at diagnosis could be a key factor in predicting how well patients will respond to standard therapies. Chronic myeloid leu

https://www.stemcellcenter.lu.se/article/new-findings-reveal-why-some-chronic-myeloid-leukemia-patients-respond-better-treatment - 2025-12-15

On October 18, 2024, two researchers from Lund Stem Cell Center were awarded funding from the Mats Paulsson Foundation for Research, Innovation, and Societal Development. A total of 16 million SEK was distributed to life science projects across Skåne, with a focus on advanced therapy medicinal products (ATMPs). This year, the foundation, which supports research with "high innovation potential and

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-researchers-secure-grants-innovative-stem-cell-projects - 2025-12-15

Malin Parmar, professor of cellular neuroscience, along with three researchers in Italy and Denmark, has been awarded the prestigious ERC Synergy Grant worth EUR 10 million. The four researchers aim to develop custom-made neurons from stem cells for cell therapies to treat Parkinson’s or Huntington’s disease. Congratulations!“Thank you, it feels really fun and exciting for many reasons! One reason

https://www.stemcellcenter.lu.se/article/erc-synergy-grant-awarded-development-custom-made-stem-cell-therapies - 2025-12-15

The Lund Stem Cell Center at Lund University has relaunched its Professional Development Program (PDP), which provides PhD students support beyond research, equipping them with the personal and professional skills essential for long-term career success. While most doctoral programs focus on scientific expertise, the PDP broadens that approach by equipping students with skills for career growth, se

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-relaunches-professional-development-program-phd-success - 2025-12-15

Jenny Hansson, associate professor at Lund University, has been awarded an 11 million SEK grant from the Swedish Society for Medical Research (SSMF). This five-year SSMF Consolidator Grant will support her research into acute leukemia, focusing on uncovering the biological differences between childhood and adult forms of the disease. Why does childhood leukemia behave so differently from adult leu

https://www.stemcellcenter.lu.se/article/jenny-hansson-awarded-11-million-sek-swedish-society-medical-research - 2025-12-15

After 20 years of research on gene therapy and the rare blood disease, Diamond–Blackfan Anemia, DBA, researcher Johan Flygare had reached a point where he and his colleagues had done everything they could in the lab. Even though they had proof of concept their gene therapy would work, engaging companies had been difficult. Then, in 2021, he received an e-mail. The message came from American entrep

https://www.stemcellcenter.lu.se/article/science-start-developing-gene-therapy-rare-blood-disorder - 2025-12-15

Outside the different examining rooms at paediatric oncology unit 64 hang laminated name signs with rainbows, unicorns and tractors that the young patients have made themselves. Each year, the unit receives around 60 new paediatric cancer patients from southern Sweden requiring examination or treatment. Of these, 85 per cent survive. Kees-Jan Pronk shares his time between being a doctor in paediat

https://www.stemcellcenter.lu.se/article/all-energies-fighting-pediatric-cancer - 2025-12-15

Researcher Emma Hammarlund realized that geological measurement methods can also be used for medical purposes. With a simple hair sample, she hopes to find cancer at an early stage. First in the study are prostate cancer and breast cancer. Now her project has been selected for the Royal Swedish Academy of Engineering Sciences' (IVA) 100 list. The list also includes eight other research projects fr

https://www.stemcellcenter.lu.se/article/ivas-100-list-hair-analysis-find-cancer-early-stage - 2025-12-15

By presenting cancer research as a battle between good and evil – and himself as a hacker attacking cells to make them kind, PhD student Luís Oliveira took home the win in the Researchers' Grand Prix. His win is the fifth in a row for Lund University and the second in a row for Lund Stem Cell Center - in the competition where researchers from all over the country challenge each other in presentati

https://www.stemcellcenter.lu.se/article/win-fifth-time-row-luis-oliveira-wins-researchers-grand-prix - 2025-12-15

A team of international researchers led by Professor Johan Jakobsson at Lund University has secured a 52 million SEK grant from the Aligning Science Across Parkinson’s (ASAP) initiative, in partnership with the Michael J Fox Foundation to investigate how mobile genetic elements —commonly referred to as "jumping genes"—contribute to neuroinflammation and the progression of Parkinson’s disease. Jump

https://www.stemcellcenter.lu.se/article/52-million-sek-goes-uncovering-genetic-drivers-parkinsons-disease - 2025-12-15

Ska genetikforskare informera forskningsdeltagare om de upptäcker sjukdomsrisker hos deltagarna? Ja, skulle många säga, om informationen är till nytta för deltagarna. Men hur vet vi om komplex genetisk information är relevant för enskilda människor? Enligt Jennifer Viberg Johansson, aktuell med en ny avhandling i forsknings- och bioetik, behöver både etiker och genetiker förhålla sig till att nytt

https://www.diabetesportalen.lu.se/artikel/genetisk-risk-ska-forskare-beratta - 2025-12-15

Örebroforskare har identifierat tidiga förändringar i ämnesomsättningen hos barn som senare utvecklar typ 1-diabetes – ett viktigt steg för att kunna förebygga sjukdomen. Detta är ett av flera forskningsresultat som presenterades på Nordic Metabolomics Conference. – Vi har identifierat tidiga förändringar när det gäller ämnesomsättningen av fett som påverkar immunsystemet. Dessa förändringar sker

https://www.diabetesportalen.lu.se/artikel/forandringar-i-amnesomsattningen-paverkar-immunforsvaret-0 - 2025-12-15

Råg, havre eller vete spelar ingen större roll. Bara de innehåller fullkorn så skyddar de mot typ 2-diabetes. En portion havregrynsgröt och en fullkornsmacka om dagen räcker för att minska risken för diabetes med 34 procent hos män och 22 procent hos kvinnor, visar en stor nordisk studie. Studien, gjord av forskare på Chalmers och Cancerinstitutet i Köpenhamn ger en kraftfull bekräftelse av tidiga

https://www.diabetesportalen.lu.se/artikel/fullkorn-basta-skyddet-mot-typ-2-diabetes - 2025-12-15