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Antineutrophil cytoplasm autoantibodies (ANCA) directed against bactericidal/permeability-increasing protein (BPI) are common in patients with cystic fibrosis (CF), and serum levels are correlated with lung colonization by Pseudomonas aeruginosa and the severity of lung damage. The production of BPI-ANCA may be due to the costimulation of BPI when mounting an immune response against P. aeruginosa.

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Research on management consultancy usually emphasizes the rote and perspective of the consultants. Whilst important, consultants are only one element in a dynamic relationship involving both consultants and their clients. In much of the literature, the client is neglected, or is assumed to represent a distinct, immutable entity. In this paper, we argue that the client organisation is not uniform b

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Classical continuum mechanics is used extensively to predict the properties of nanoscale materials such as graphene. The bending rigidity, kappa, is an important parameter that is used, for example, to predict the performance of graphene nanoelectromechanical devices and also ripple formation. Despite its importance, there is a large spread in the theoretical predictions of kappa for few-layer gra

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By catalyzing hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), cyclic nucleotide phosphodiesterases are critical regulators of their intracellular concentrations and their biological effects. As these intracellular second messengers control many cellular homeostatic processes, dysregulation of their signals and signaling pathways initiate or modulate p

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Despite weak evidence, the use of acupuncture has increased in infantile colic. The only three randomized trials conducted evaluated standardized minimal acupuncture in one single point. Two showed effect but one did not so further research is necessary. The aims of the study are 1) to test if results in earlier trials conducted in private acupuncture clinics can be repeated at Child Health Center

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This contribution highlights recent results from the PHENIX Collaboration at RHIC with emphasis on those obtained through lepton and photon measurements in PHENIX.

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An ultrastructural study of the intestine of Derocheilocaris typica revealed an organization of the midgut musculature, which is unique in the Crustacea. This species unusual anal skeletomusculature has also not been seen before. The intestinal musculature of D. typica displays different patterns in the fore-, mid-, and hindgut. Around the foregut, eight pairs of dilator muscles complement a conti

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High-quality GaSb nanowires (NWs) have been synthesized via chemical vapor deposition. The as-synthesized NWs have a zinc-blende structure with growth direction along a < 011 > direction. Raman spectrum of the GaSb NWs consists of two peaks, corresponding to the LO and TO phonon modes, respectively. The temperature dependence of the photoluminescence spectra shows a blue-shift as the temperature d

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Project retrospectives can be powerful tools for project teams to collectively identify communication gaps and practices to improve for future projects. However, even if project members take the time for a retrospective, it can be hard to correctly remember and jointly discuss past events in a constructive way. Fact-based timelines that visualize a project's events offer a possible solution.

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A book printer and a bookseller in Copenhagen – Claude Philibert’s connection with the Societé typographique de Neuchatel 1771-1783. In 1755 Claude Philibert came from Geneva to Copenhagen, where he establishedhimself as a bookseller. Until the 28th of April 1775 he was also a partner in a publishing bookshop and printer’s business in Geneva, which was run by Barthélemy Chirol. On the 3rd of Augus

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Dynamics of laser-induced plasma plume studied by cavity ring-down spectroscopy (CRDS) was simulated by a numerical model. Velocity distribution and anisotropy of the plume with temporal and geometrical characteristics of CRDS were included. Behavior of spectral lineshapes was studied in respect to various experimental parameters.

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Background: Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction of mRNAs bearing premature terminations codons (PTCs). Such PTC-containing (PTC+) mRNAs may arise from different processes, including erroneous processing and expression of pseudogenes, but also from more regulated events such as alternative splicing co

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Studies of epithelial cancers (i.e., carcinomas) traditionally focused on transformation of the epithelium (i.e., the cancer cells) and how aberrant signaling within the cancer cells modulates the surrounding tissue of origin. In more recent decades, the normal cells, blood vessels, molecules, and extracellular components that surround the tumor cells, collectively known as the "tumor microenviron

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The ALICE Collaboration has measured inclusive J/psi production in pp collisions at a center-of-mass energy root s = 2.76 TeV at the LHC. The results presented in this Letter refer to the rapidity ranges vertical bar y vertical bar < 0.9 and 2.5 < y <4 and have been obtained by measuring the electron and muon pair decay channels, respectively. The integrated luminosities for the two channels are L

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This article discusses how Chicago police representatives have expressed their understanding of the events at haymarket Square on the 4th of May, 1886 and the commemoration of the bombing and its aftermath in trials and hangings.

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Recension av en existentiell biografi om drottning Victoria, som fokuserar mycket på hennes religiösa liv och hennes pliktmedvetande, samt illustrerar hur hon kan betraktas som tillhörande "förlorarnas historia".

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The Tree Theme Method (TTM) is an intervention based on sessions involving creative activities and life storytelling/story-making, in which the client paints trees representing various periods of his/her life. The aim of this study was to investigate clients' experiences of participating in a TTM intervention and their perceptions of the therapeutic relationship. Thematic interviews were undertake