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Take Home Message Lymph node–positive renal cell carcinoma is a heterogeneous condition. Patients with bulky or multiple nodal metastases often behave like those with metastatic disease and may benefit more from upfront systemic therapy than from surgery alone.
In this work, the electrical performance of fully vertical single-fin a-plane gallium nitride fin-based field-effect transistors (FinFETs) with short gate length (Lg≈ 200nm) and a drift-layer thickness of 4.3 µm is investigated. Device characteristics are evaluated over a temperature range from 25 °C to 150 °C for various fin widths. The FinFETs exhibit stable normally-off operation across the ent
Involving the local community in the late stages of a project offers minimal opportunity for influencing decision-making. Therefore, project managers must act early and establish arenas for participation where dialogue and learning can take place. Early involvement through stakeholder participation can be a way to involve the local community in the early stages of urban regeneration projects. A co
Aims Left ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was ther
Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Tjänstevetenskap Kurs: SEMK65- Service Management: Examensarbete för kandidatexamen Författare: Ellen Friberg & Elin Törnblom Handledare: Elisabeth Högdahl Syfte: Syftet med studien är att undersöka hur lokala aktörer uppfattar att platsidentitet kommer till uttryck genom ett återkommande evenemang, samt hur detta får betyde
Den svenska secondhandmarknaden har vuxit kraftigt under senare år och utgör idag en etablerad del av detaljhandeln. Inom golfsektorn har digitala plattformar som Golfbidder, Foremarket och Blocket gjort begagnad utrustning lättillgänglig för konsumenter, vilket förändrar förutsättningarna för golfklubbarnas egna shoppar. Trots detta saknas forskning som specifikt belyser hur golfklubbar strategis
Detta examensarbete behandlar utmattningsbedömning av åtdragningsbultar i packningsförsedda plattvärmeväxlare, med särskilt fokus på skillnaden mellan konservativa kodbaserade livslängdsprognoser och den långa livslängd som observerats i praktiken. Arbetet behandlar två utmattningsbidrag: högcyklisk driftbelastning och monteringsbelastning med större amplitud. För driftbelastningen undersöks om deThis thesis investigates fatigue assessment of tightening bolts in gasketed plate heat exchangers, with particular focus on the discrepancy between conservative code-based predictions and the long service lives observed in practice. The work addresses two fatigue contributions: high-cycle operational loading and larger-amplitude assembly loading. For the operational loading, the study examines whe
Accurate estimation of fine particulate matter (PM2.5) is essential for epidemiological exposure assessment, yet monitoring networks can be too sparse to capture spatial variation across urban areas. Existing modeling approaches address this gap using either physics-based dispersion models, which require detailed emission inventories, or machine learning models that rely on satellite aerosol optic
Wood is one of the oldest building materials used around the world. It began in more sparsely populated areas but was later established within city walls. This resulted in a factor that caused major urban fires throughout history, which sparked interest in using other building materials. However, in recent years, wood has become increasingly more attractive within the construction industry, pri
The building sector is important for Sweden’s climate mitigation efforts. Reducing emissions requires energy-efficient new buildings and sustainable renovation of existing ones. However, common envelope changes, such as thicker insulation or modified wall layers, may increase moisture accumulation and mould risk. Consequently, a comprehensive assessment of exterior walls across moisture safety, en
As the global economy fragments and geopolitical disruptions become increasingly frequent, understanding how firms strategically respond and adapt to these disruptions becomes critical. This thesis examines how A.P. Møller – Mærsk A/S has responded to geopolitical risk over time, and how these responses are indicative of organizational learning and adaptive capability development. Through a longit
This thesis examines the relationship between the climate discourse of Germany's Alternative für Deutschland (AfD) and the electoral geography of its support, asking how the party frames climate change as a threat to German identity and economic security, and whether this framing finds resonance in the districts which are most exposed to these conditions. The research addresses a gap in existi
This research examines the central theme of ‘Common People’, an episode from the seventh season of the British television series Black Mirror. The episode presents a fictional narrative in which corporations mediate and regulate human existence through a subscription-based system. The episode constructs a posthuman condition in which survival and well-being become contingent upon uninterrupted mon
This study explores how visual representations shape the cultural and emotional understanding of breast cancer. Although breast cancer is typically viewed as a biomedical disease, it is also deeply influenced by visual images that affect the disease’s visibility and construct its emotional significance. This study examines how people perceive, feel, and interpret the disease through various visual
The bone–cartilage interface, or calcified cartilage, is a thin but critical transition zone that helps distribute mechanical loads across the synovial joint. However, this interface remains difficult to visualize and segment using conventional techniques due to its structural and textural similarity to the adjacent subchondral bone. Accurate segmentation would enable quantitative analysis of the
Five-membered heterocycles are a crucial moiety in medicinal chemistry and are widely present in drugs due to its broad biological profile. Disubstituted 1,2,4-triazoles are used in a variety of therapeutic applications such as anti-cancer drugs, although the synthesis can be challenging. Previously, synthetic routes required harsh conditions and small range of reagents, which limits the scope of
Urea formaldehyde foam (UFF) is an amino-based thermoset plastic that is widely used for dry flower arrangement and decoration. Much research has been conducted to minimize the risks associated with formaldehyde emissions and recycling practices to properly dispose or re-utilize the cured UFF; however, limited research has been conducted to enhance the biodegradability of the resin. This study aim
Per- and polyfluoroalkyl substances (PFAS) possess exceptional chemical stability due to their strong carbon–fluorine bonds, resulting in environmental persistence and degradation challenges. Therefore, developing efficient methods for carbon-fluorine bond cleavage is essential for future recycling and remediation strategies. This work investigates lanthanide-mediated reductive defluorination of 1
The advance of quantum computing poses a fundamental threat to today's cryptographic systems. The American agency NIST advocates that all cryptographic systems transition to post-quantum cryptography (PQC) by 2035 and even earlier for more critical systems. Given the threat of harvest-now-decrypt-later attacks, there is a growing urgency for any system handling sensitive data to migrate to PQC
This thesis explores the use of Reinforcement Learning (RL) to optimize residential energy usage in a system composed of photovoltaic (PV) panels, a battery, an electric vehicle (EV), household consumption, and the electricity grid. A Deep Q-Network (DQN) agent was developed to minimize the electricity bill by optimizing battery usage and EV charging using real residential data supplied by Siemens
