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Mechanisms of injury and repair in alveolar epithelial cells (AECs) are critically involved in the progression of various lung diseases including idiopathic pulmonary fibrosis (IPF). Homeobox only protein x (HOPX) contributes to the formation of distal lung during development. In adult lung, alveolar epithelial type (AT) I cells express HOPX and lineage-labeled Hopx+ cells give rise to both ATI an
Sound physical health is a critical component of the human development process, wherein early life and childhood are pivotal periods. Although child health in sub-Saharan Africa has been improving for the past few decades, the region still has the highest mortality rate for children under five as well as high levels of child morbidity. The most immediate causes of these poor health outcomes are in
How temperature influences development has direct relevance to ascertaining the impact of climate change on natural populations. Reptiles have served as empirical models for understanding how the environment experienced by embryos can influence phenotypic variation, including sex ratio, phenology and survival. Such an understanding has important implications for basic eco-evolutionary theory and c
Attosecond pulses are short enough to capture the electronic dynamics in atoms and molecules. The work presented in this thesis deals with the generation and optimization of attosecond extreme-ultraviolet (XUV) pulses. The goal is to progress towards the realization of time-resolved nonlinear experiments at the intense XUV beamline of the Lund High-Power Laser Facility.The XUV flux was optimized u
Aims/hypothesis: Coronary artery disease (CAD) is a common complication among individuals with diabetes. A better understanding of the genetic background of CAD in this population has the potential to suggest novel molecular targets for screening, risk assessment and drug development. Methods: We performed a genome-wide association study of CAD in 15,666 unrelated individuals (3,968 CAD cases and
In the primary school classroom, children are exposed to multiple factors that combine to create adverse conditions for listening to and understanding what the teacher is saying. Despite the ubiquity of these conditions, there is little knowledge concerning the way in which various factors combine to influence listening comprehension and the effortfulness of listening. The aim of the present study
Planning and execution of large infrastructure projects benefit from detailed mapping of the subsurface through geophysical methods. However applying geophysical methods in an urban environment requires careful preparation to ensure success in areas where source of noise and present infrastructure may compromise the results. We present and discuss the results of a seismic investigation conducted i
Artikeln behandlar översiktigt arkitektur, porträttkonst, makt och historiebruk från Gustav Vasa till drottning Kristina. I den görs också utvikningar som relaterar den svenska utvecklingen inom området till den på kontinenten. En sammanfattning av övergången från medeltid till renässans till i Sverige ingår liksom en utblick på vad som sker inom arkitekturen i Skåne som vid tiden var danskt, samt
Home care services are an important part of the Swedish social welfare system. Considering the size of the sector and the increasing future needs for home care, due to growing elderly populations, it is worrisome that problems in terms of injuries, sick leave and staff turnover appear common in this occupation. A problem for managing the situation is, however, that the current knowledgebase is fra
This report presents a proposal for a classification of generic properties of systems and an application to construction objects. The background is a documented need for classification expressed in international construction co-operation within ISO, IFC and other standardisation efforts, to be used in different applications like classification systems and product libraries. The general property cl
