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Continuous access to flows of goods and services, such as energy, transport, information, and food, is essential and the basis for functioning modern societies. Hence, they are critical and need to be secured. Mega-trends such as climate change, changing geopolitical environment, hybrid- and cyber threats, and rapid technological advances come with new challenges and emerging threats to securing f
Wild insect pollinators are essential to cultivated and natural ecosystems globally. Today, many pollinator species are declining. One reason is a general lack of flowering habitats at landscape scales. However, urban areas, including private gardens, may provide flowers, and constitute beneficial habitats for pollinators. Here, we evaluate the ecological outcomes of a citizen science campaign run
The structure and organization of a tumor and its microenvironment are often associated with cancer outcomes due to spatially varying molecular composition and signaling. A persistent challenge is to use this physical and chemical spatial organization to understand cancer progression. Here, we present a high-definition infrared imaging–based organizational measurement framework (INFORM) that lever
BACKGROUND: Many children with juvenile idiopathic arthritis (JIA) have autoantibodies, targeting nuclear components (anti-nuclear antibodies, ANA). ANA in JIA is associated with uveitis, an eye inflammation which may cause permanent vision impairment if not detected and treated. However, ANA-testing is neither specific nor sensitive enough to be a clinically reliable predictor of uveitis risk, an
This article discusses the reconfiguration of citizenship education in the Swedish Boy Scout movement, one of the country’s largest civil society organizations, after 1945. Citizenship education was a core feature of scouting since its establishment during the first decades of the twentieth century, with patriotism and practical helpfulness as core tenets. Additionally, an emphasis on hiking and cThis article discusses the reconfiguration of citizenship education in the Swedish Boy Scout movement, one of the country’s largest civil society organizations, after 1945. Citizenship education was a core feature of scouting since its establishment during the first decades of the twentieth century, with patriotism and practical helpfulness as core tenets. Additionally, an emphasis on hiking and c
Wetlands are valuable natural capital and sensitive ecosystems facing significant risks from anthropogenic and climatic stressors. An assessment of the environmental risk levels for wetlands’ dynamic ecosystems can provide a better understanding of their current ecosystem health and functions. Different levels of environmental risk are defined by considering the categories of risk and the probabil
Bidraget visar hur man i retorikutbildning kan stödja studenters livslånga lärande och förmåga till egen kompetensutveckling. Skriftliga reflektioner lyfts fram som ett didaktiskt redskap och samarbete med arbetslivskoordinator som ett sätt att stärka utbildningens relevans och överbrygga gränsen mellan utbildning och yrkesliv.
BACKGROUND: Diabetes is associated with inner ear dysfunction. Furthermore, C57BL/6J mice fed high fat diet (HFD), a model for insulin resistance and diabetes, develop endolymphatic hydrops (EH).AIM: Evaluate if betahistine, spironolactone (aldosterone antagonist) and empagliflozin (sodium -glucose cotransporter2 inhibitor) can prevent EH induced by HFD and explore potential mechanisms.METHODS: C5
Background: Cancer immunity is based on the interaction of a multitude of cells in the spatial context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated to fundamentally improve the accuracy in predicting disease progression. Methods: Through a multiplex in situ analysis we evaluated 15 immune cell classes in 1481 tumour samples. Single-cell and bulk RNAseq data
