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A large part of new pharmaceutical substances are characterized by a poor solubility and high hydrophobicity, which might lead to a difference in drug adsorption between fasted and fed patients. We have previously evaluated the release of hydrophobic drugs from tablets based on Pemulen TR2 and showed that the release can be manipulated by adding surfactants. Here we further evaluate the possibilit
Abstract in UndeterminedThe aim of this study was to evaluate the extent to which water use efficiency (WUE) at leaf scale can be used to assess WUE at canopy scale, leaf WUE being assumed to be a constant function of vapor pressure deficit and to thus not be dependent upon other environmental factors or varying leaf properties. Leaf WUE and its variability and dependencies were assessed using lea
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Free space optics is an interesting alternative for telemetry with medical implants, due to the high data bandwidths available at optical frequencies. Especially implanted brain-computer interfaces gives rise to large data sets that needs to be transmitted transcutaneous. In this paper we show that it is possible to establish such a link at near-IR wavelengths using a modulated reflector in the im
Abstract Levels of natural radioactivity such as 222Rn (radon) and its long-lived daughters 210Pb and 210Po were measured. The radon gas was trapped on cooled charcoal filters and the long-lived daughter products sampled on fibre filters on a daily basis. In addition, short-lived progenies were followed continuously on the filters in order to achieve a time resolution of about one hour. The ave
The initial growth of MnBi on MnAs-terminated (GaMn)As is studied by means of synchrotron-based photoelectron spectroscopy. From analysis of surface core-level shifts we conclude that a continued epitaxial MnBi layer is formed, in which the MnAs/MnBi interface occurs between As and Bi atomic planes. The well-defined 1×2 surface reconstruction of the MnAs surface is preserved for up to 2 ML of MnBi
Surgical staff is considered to have several ergonomic risk factors, but their physical workload and musculoskeletal health have seldom been evaluated. Clinical examinations of neck and upper extremities were performed in 99 theatre nurses and 93 assisting nurses, all females. Their physical workload was assessed by questionnaire, and by technical measurements of postures, movements and muscular l
Almost every day a school fire occurs in Sweden. In most cases arson is the cause of the fire. The losses for these arson fires are considerable. In this report a number of cases studies have been conducted on school fires in Sweden. The project envisages obtaining more knowledge on the technical factors that influence the spread of fires with arson in schools. Solutions to mitigate the fire sp
Political institutions are keen to use the best available scientific knowledge in decision-making. For environmental policy, relevant scientific evidence can be complex and extensive, so expert judgment is frequently relied upon, without clear links to the evidence itself. We propose a new transparent process for incorporating research evidence into policy decisions, involving independent synopsis
To better understand prostate function and disease, it is important to define and explore the molecular constituents that signify the prostate gland. The aim of this study was to define the prostate specific transcriptome and proteome, in comparison to 26 other human tissues. Deep sequencing of mRNA (RNA-seq) and immunohistochemistry-based protein profiling were combined to identify prostate speci
A search for neutral Higgs bosons decaying to pairs of tau leptons with the ATLAS detector at the LHC is presented. The analysis is based on proton-proton collisions at a center-of-mass energy of 7 TeV, recorded in 2010 and corresponding to an integrated luminosity of 36 pb(-1). After signal selection, 276 events are observed in this data sample. The observed number of events is consistent with th
Välfärdstjänsterna har antagit formen av marknadsbaserade tjänster på grund av en ökad marknadsorientering. I artikeln analyseras vad valfrihet gällande välfärdstjänster kan innebära för medborgaren i olika socioekonomiska positioner genom att fokusera faktorer som kan begränsa valmöjligheter. En slutsats är att både resursstarka och resurssvaga har begränsade valmöjligheter. En annan slutsats är
Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless, there are only a few studies on the molecular basis underlying aptamer-protease interactions and th
Prenatal testosterone surge is considered crucial for physiological masculinization of male progeny. Disorders in sex steroid hormone balance during the fetal development may interfere with male reproductive health later in life. In this study, we have investigated in utero and in vitro effects of flutamide (FLU) and diethylstilbestrol (DES) on fetal rat testicular steroidogenesis. In utero exposu
The unauthorized migration of construction workers to Sweden increased during the 1990s, especially at the end of the decade. The migrants often came from Poland and the Baltic states. The aim of this article is to examine this change of the migration pattern to Sweden and how the Swedish Building Workers Union responded to this new situation. I examine how the Building Workers Union cooperated wi
In this study calorimetric measurements provided evidence of a drastic increase of spinach leaf gross metabolism as a consequence of vacuum impregnation (VI) at a minimum pressure of 150 mbar with trehalose and sucrose isotonic solutions. When applying VI extracellular air is replaced by the impregnation solution, potentially limiting tissue respiration to any remaining air volume in the tissue. H
Popular Abstract in Swedish Bakgrund Man kan fråga sig varför en hel avhandling handlar om något så ovanligt som akut mastoiditit hos barn. Det är den vanligaste komplikationen till öroninflammation men drabbar bara 20-60 barn per år i Sverige. Öroninflammation däremot är en infektion som är så vanlig att nästan alla har haft åtminstone en sådan som barn. I Sverige diagnostiseras upp emot 200 000 One of the greatest threats to society today is the development of bacterial resistance to antibiotics. It is commonly accepted that this is mainly due to the use of antibiotics. Acute otitis media (AOM) is responsible for the highest number of antibiotic prescriptions to children although it is in most cases a self-limiting disease. Nevertheless, complications do occur in some case and the most c
The blood parasite diversity was studied in paddyfield warblers (Acrocephalus agricola) breeding in NE Bulgaria, SW Russia and S. Kazakhstan. Nine cytochrome b gene lineages were recorded, 4 belonging to Haemoproteus spp. and 5 to Plasmodium spp. The overall prevalence of haemosporidians was 33.3%. The composition of parasites varied geographically, with six lineages recorded in Russia, five linea
