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In many machine learning tasks, the premise is designed around predetermined targets and clear expectations of model behaviour. In such cases, there is a direct definition of the optimal mappings between inputs and outputs, which can be learned given sufficiently sized datasets and models. However, in many real-world scenarios, tasks are often not as well-posed and instead defined around detecting
Oligometastatic squamous-cell carcinoma of the anus (omSCCA) is a very rare condition. The literature is sparse, and treatment guidelines are lacking. The aim of the present work was to carry out a literature review and to propose an algorithm for intensified treatment of patients with omSCCA. A PubMed search was carried out, which resulted in 15 relevant publications that included any type of def
Mobility is essential to our modern world to move people and goods. However, mobility has also its downside as transport sectors are substantial emitters of greenhouse gases and air pollutants. Increasingly energy efficient combustion engines and turbines, as well as electrification and carbon-neutral fuels, will reduce the climate impacts of transportation. When such technologies are combined wit
This article adds to the growing body of literature on the #MeToo movement in non-Western contexts. It explores the concept of resilience in the context of workplace sexual harassment in China, drawing on 26 cases from the #MeToo in China Archives (2018–2019). Using thematic analysis, the study examines the actions of the harassed individuals, the support they received, and how they handled and co
Injury prevention programmes can reduce injuries in youth team sports, including handball. However, real-world effectiveness and impact of such programmes are limited due to poor implementation. To address this in Swedish youth handball, the 'Implementing injury Prevention training ROutines in TEams and Clubs in youth Team handball' (I-PROTECT) programme was co-created with end-users, including co
Rapporten analyserar internationella erfarenheter av alternativa modeller för finansiering och organisering av transportinfrastruktur i ett urval av länder som liknar Sverige i institutionellt och geografiskt hänseende. Fokus ligger på offentlig–privat samverkan (OPS) och statliga projektbolag. Syftet är att identifiera vilka institutionella, ekonomiska och organisatoriska faktorer som påverkar ut
Issues of quality, value, and merit are perpetually lively and contentious in scientific and academic work, and research on evaluation panels have shown that organizational constraints and the methods of evaluation used, whether well-motivated or adopted ad hoc, have enormous influence on outcomes. But while previous studies have highlighted the influence exerted by particular methods of evaluatio
Many audio applications, including echo-cancellation and active noise control, rely on the availability of accurately estimated room impulse responses (RIRs). For these applications, it is common that the source signal is short and primarily consists of speech or music, which may cause the estimation of the RIR to be poorly conditioned. Although priors on the amplitudes of the RIR could in princip
OBJECTIVE: Thyroid hormones control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage and time window remain elusive.METHODS: Stroke was induced in mice by transient middle cerebral art
BACKGROUND: The discrepancy between experimental research and clinical trial outcomes is a persistent challenge in preclinical studies, particularly in stroke research. A possible factor contributing to this issue is the lack of standardization across experimental stroke models, leading to poor reproducibility in multicenter studies. This study addresses this gap by aiming to enhance reproducibili
År 2023 var 18 800 barn placerade i familjehem. Gemensamt för dessa barn är att de under en tid upphör att dela vardag med sin ursprungsfamilj. Att i en sådan situation upprätthålla relationen till föräldrarna innehåller en rad utmaningar. I kapitlet har vi belyst dessa utmaningar utifrån följande perspektiv: lagstiftning, teorier och erfarenheter från placerade barn, föräldrar, familjehemsföräldr
BackgroundAchieving safe and stable placements is a key mission for the foster care system. Foster parents and social workers are part of a caregiving network with responsibility for the child and their wellbeing. Emotionally dysregulated children's behaviors may pose a challenge to the caregiving system. Trauma-informed care (TIC) interventions aim at enhancing caregivers' understanding of such b
In architecture and urban geography, discussions on repair, maintenance and adap5ve re-usehave emerged as a crucial intellectual terrain. Temporal aspects of how the urban fabric isused have also emerged as an issue worth theore5cal and empirical a=en5on. Latching ontothese themes, we will present work tracking the history of conten5on around the publiclyowned mee5ng and arts venue in Lund’s Peopl
Despite years of encouraging translational research, ischemic stroke still remains as one of the highest unmet medical needs nowadays, causing a tremendous burden to health care systems worldwide. Following an ischemic insult, a complex signaling pathway emerges leading to highly interconnected thrombotic as well as neuroinflammatory signatures, the so-called thromboinflammatory cascade. Here, we
