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Early diagnosis of colorectal cancer (CRC) is crucial for successful treatment and mortality reduction. In this regard, blood-based tests play an indispensable role. Current research is focused on molecules actively secreted by tumor cells into small extracellular vesicles (EVs). This four-phase study included 613 CRC patients, 446 controls, and 120 precancerous lesions. High-throughput transcript
Climate change is primarily driven by anthropogenic emissions of greenhouse gases. Reducing these emissions globally requires a massive effort at the individual, city, and national scales. Urban areas are hotspots of anthropogenic emissions, given the high density of human-based activities, and clarity on the variations of emissions in these areas will enable effective targeted reduction plans. Ho
We study gender differences in the response to losing competitions using an online experiment (N=2,086). We find that both genders reduce tournament entry rates in response to losses that are unequivocally meritocratic. However, when the winner is not necessarily determined by merit—a setting perceived as less fair than the meritocratic tournament—female losers are relatively more discouraged. The
The EU’s recent regulatory approach in the digital sphere promises to introduce greater consideration for fundamental rights. However, this does not apply to all fundamental rights and their holders equally. With particular focus on the freedom to conduct a business, this article will be exploring the restrictions imposed on certain undertakings—so-called gatekeepers—operating in the Digital Singl
All over the developed world there is a SES gradient in health and mortality for adults. Thesemortality differentials have also widened since the 1970s in the countries for which there aredata. Our knowledge about conditions in the more distant past is much more rudimentary, andwe do not know when and why the mortality gradient emerged. In this paper we studydifferences in life expectancy at age 6
By optically sensing mid-infrared absorption through a visible probe beam, mid-infrared photothermal (MIP) microscopy has emerged as a powerful tool for chemical imaging with micromolar sensitivity and submicron spatial resolution. The adoption of spatially multiplexed camera-based widefield detection further enhanced the imaging speed. However, current widefield MIP systems suffer from a small fi
There is a strong mortality gradient by socioeconomic status in most of today’s developedcountries, which has spurred both scientific and policy interest. Despite its importance, westill do not have a full understanding of the causes of this gradient, nor about when itemerged. In this paper we study socioeconomic differences in adult mortality for men andwomen in Sweden over an almost 200-year per
Groundwater depletion, driven by population growth and climate change, poses a critical challenge to global water security, particularly in arid and semi-arid regions. This chapter explores groundwater artificial recharge with unconventional water (GARUW) as a transformative strategy to replenish stressed aquifers. A spectrum of unconventional resources, including treated wastewater, stormwater, d
Since the rise of Trumpism, debates in Washington have come to resemble the grotesque dialogues of Aristophanes’ political satires more and more. Has this had an impact on the legislative effectiveness of freshman Republican Con-gressmembers? That is the question this paper seeks to answer. Starting from a dataset comprising all freshmen Republicans serving from 2001 to 2025, a com-posite Legislat
This thesis explores how the heterotopic and liminal dimensions of Munich’s Oktoberfest produced differentiated visitor experiences, and how spatial, temporal, ritual, and social dynamics mediate feelings of authenticity, communitas, and belonging across visitor types. Adopting an interpretivist, social constructionist approach, the thesis combines semi-structured interviews with 15 participants a
Research on trust in consumer-to-consumer second-hand platforms has traditionally focused on fixed buyer and seller roles, which may not capture the experiences of users who switch between both roles as prosumers. This study explores how trust is experienced and shaped by prosumers on the Chinese platform Xianyu. An integrated theoretical framework combines Service Dominant Logic with Institutiona
The multitaper spectrogram, with arithmetic and geometric mean functions, and the ambiguity domain where evaluated on simulated data and real audio samples{. This was done} to determine if they can improve the results, of classification tasks, of the single-taper spectrogram when used as input to a convolutional neural network. The spectrogram used was differentiable to allow for the window length
This study examines how the institutional and governance arrangements established under Namibia's Communal Land Reform Act (CLRA) of 2002 shape the equitable administration of indigenous communal land rights, with particular focus on the San community. Drawing on institutional theory and property rights theory as complementary analytical frameworks, and employing qualitative document analy
Land inequality remains a pressing global issue, and redistributing land is widely regarded as an important tool for reducing poverty and promoting rural development. Prior land redistribution efforts have produced inconsistent results, raising questions about the factors shaping implementation effectiveness. This thesis examines how the landed elite, a group whose power is rooted in landownership
Long recognized as a global climate leader, Sweden has in recent years experienced significant regression across multiple areas of climate policy. Since taking office in 2022, the Swedish government has enacted policies that stand in stark contrast to its electoral pledges, employing strategies that raise questions about the underlying motives and objectives of its climate agenda. This study exami
Universities are widely understood to be sites of free expression, knowledge-seeking institutions that serve the public good while encouraging personal development of individuals. They typically uphold and communicate institutional integrity and ethics, seeking to encourage open communication, equip students with critical thinking, and foster civil participation. For the Social Sciences, questions
The Unit for Clinical Epidemiology at Lund University conducts research into the molecular mechanisms of osteoarthritis. To facilitate this research, standardized tissue samples in the form of small osteochondral plugs must be extracted from larger, heterogeneous donor samples obtained from the Lund Tissue Bank. However, human bone samples are inherently hard and fragile. Current suboptimal extrac
