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In the management of Parkinson's disease, reliable diagnostic and prognostic biomarkers are urgently needed. The diagnosis of Parkinson's disease mostly relies on clinical symptoms, which hampers the detection of the earliest phases of the disease—the time at which treatment with forthcoming disease-modifying drugs could have the greatest therapeutic effect. Reliable prognostic markers could help
Background: The clinical importance of immediate coronary angiography, with potentially subsequent percutaneous coronary intervention (PCI), in out-of-hospital cardiac arrest (OHCA) patients without ST-elevation on the ECG is unclear. In this study, we assessed feasibility and safety aspects of performing immediate coronary angiography in a pre-specified pilot phase of the ‘DIrect or Subacute Coro
This paper presents the findings of the workshop “New approaches to evacuation modelling”, which took place on the 11th of June 2017 in Lund (Sweden)within the Symposium of the International Association for Fire Safety Science (IAFSS). The workshop gathered international experts in the field of fire evacuation modelling from 19 different countries and was designed to build a dialogue between the f
5-Hydroxymethylfurfural (HMF), a product of catalytic dehydration of C6 sugars, is a versatile and key renewable platform chemical. The possibility to use a high substrate concentration with high yield in a single-solvent system is one of the solutions to reduce solvent usage, energy consumption, reaction volume, and operating cost. A heterogeneous catalyst and single-solvent system were employed
Phase modulation and phase cycling schemes have been commonly used in electronic two-dimensional (2D) spectroscopy where the observables are incoherent signals such as fluorescence or photocurrent. Although the methods have distinct advantages compared to the coherent signal-detected 2D spectroscopy in sensitivity, possibility to measure spectra from isolated quantum systems and direct visualizati
Syntolkning erbjuder personer med synnedsättning och blindhet en rikare upplevelse av exempelvis film och gör det lättare för användare att förstå och leva sig in i vad som händer. Syntolkens främsta uppgift är att beskriva det som syns men inte hörs. Bidraget fokuserar på syntolkning av en narrativ filmscen ur ett produktionsperspektiv (hur syntolkar gör) och receptionsperspektiv (hur syntolkning
Photoluminescence (PL) of CH 3 NH 3 PbI 3
Lymphoid specification is the process by which hematopoietic stem cells (HSCs) and their progeny become restricted to differentiation through the lymphoid lineages. The basic helix-loop-helix transcription factors E2A and Lyl1 form a complex that promotes lymphoid specification. In this study, we demonstrate that Tal1, a Lyl1-related basic helix-loop-helix transcription factor that promotes T acut
Although significant improvements have been achieved for organic photovoltaic cells (OPVs), the top-performing devices still show power conversion efficiencies far behind those of commercialized solar cells. One of the main reasons is the large driving force required for separating electron-hole pairs. Here, we demonstrate an efficiency of 14.7% in the single-junction OPV by using a new polymer do
We implement Bayesian model selection and parameter estimation for the case of fractional Brownian motion with measurement noise and a constant drift. The approach is tested on artificial trajectories and shown to make estimates that match well with the underlying true parameters, while for model selection the approach has a preference for simple models when the trajectories are finite. The approa
We have used two-photon Fourier transform spectroscopy to investigate the first singlet excited state (S1) of a prototypical polyene molecule 1,5—Diphenyl-1,3,5-hexatriene. As the S1 state in the polyenes is a one-photon forbidden transition, the structure of its vibrational levels cannot be studied using resonant linear excitation. Although this level is accessible with two-photon excitation, pre
