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BACKGROUND: Asthma guidelines recommend that long-acting inhaled beta-agonists should be used as maintenance therapy for patients with asthma inadequately controlled on an inhaled corticosteroid. We studied the safety and efficacy of the long-acting beta-agonist formoterol compared with terbutaline, each taken as needed, in patients with moderate to severe asthma. METHODS: Patients were taking an
PRR recognize conserved structures on pathogenic microbes and are important for the defense against invading microorganisms. However, accumulating evidence indicates that many pathogens have evolved mechanisms to avoid recognition by PRR. One type of PRR is the macrophage scavenger receptor A (SR-A), which has been shown to play an important role in recognition and non-opsonic phagocytosis of path
In an earlier study, we found that Swedish-speaking children with specific language impairment (SLI) differ from younger normally developing compatriots on only a subset of verb morphemes characteristically problematic for children with this type of disorder. In the present study, this finding was replicated, using a carefully devised set of tasks to elicit attempts at the target morphemes. The ch
PURPOSE: This study of patients with minor head injury was designed to investigate the relation of S-100 protein measurements to computed tomograpy (CT) findings and patients outcomes. Increased serum levels of this protein were hypothetized to predict intracranial pathology and increased frequency of post-concussion symptoms. METHODS: One hundred and eighty-two patients were studied with Glasgow
Objective. The P190 and P210 BCR/ABL1 fusion genes are mainly associated with different types of hematologic malignancies, but it is presently unclear whether they are functionally different following expression in primitive human hematopoietic cells. Materials and Methods. We investigated and systematically compared the effects of retroviral P190 BCR/ABL1 and P210 BCR/ABL1 expression on cell prol
Ensuring fatherhood is an important issue in polygamous species. In many lepidopteran species, the male inserts a large package (spermatophore) consisting of sperm, accessory gland fluids and nutrients into the female's bursa copulatrix during copulation. In most species it has been shown that a large mate donation causes females either to stop calling, or to prolong the time until re-mating, here
The aim of this work was to show the applicability of light diffraction tomography on airborne ultrasound. Different air-coupled transducers in the frequency range 40 kHz - 2 MHz were measured to show the method's performance. A calibrated microphone and the pulse-echo method were used to evaluate the results. The absolute measurements agreed within the calibrated microphone's uncertainty range. P
Growing of vegetables in the field, harvesting, handling in the packing house and storage are events in the lifetime of vegetables that arc analysed from the point of view of the complex series of physiological transitions taking place in each of these events. Water is the major factor limiting plant metabolism and plants have developed fascinating mechanisms to cope with this limiting factor. The
The design of PI controllers for systems with interacting loops is discussed. It is advantageous to deal with the interaction at the loop level, because supervisory control seldom has sufficient bandwidth. A new scheme based on modified scalar PI design and static decoupling is developed, in which the frequency characteristic of the coupling between the lower-level loops is taken into account. Thi
Swedish cross-sectional survey data on young individuals aged 12-18-year-old was used to analyse school-class based peer effects in binge drinking, smoking and illicit-drug use. Significant and positive peer effects were found for all three activities. By introducing school/grade fixed effects, the estimated peer effects were identified by variation in peer behaviour across school-classes within s
Background: Photoallergic contact dermatitis from ketoprofen has been recognized since the mid-1980s. Skin reactions have been reported to continue weeks after discontinuation of ketoprofen. One reason for this could be residual ketoprofen in the skin, which has been shown in a skin biopsy specimen. Objective: We sought to report on 3 cases of photoallergic contact dermatitis from ketoprofen in to
Early B-cell factor (EBF) is a DNA binding protein required for early B-cell development. It activates transcription of several B-cell-specific genes, including the {lambda}5 gene, which encodes a protein necessary for signaling by the pre-B-cell receptor. In an effort to understand the mechanism by which EBF activates transcription, we examined its interaction with the coactivator protein p300/CB
It is known for a fact that the far-field boundary causes expensive computer calculations, when applying the finite element method to Maxwells equations. The reason is of course that a magnetic potential of some kind must be forced to zero at an appropriate distance from the disturbance, in electromagnetics the conductor. Various methods have been examined to reduce the cost of these calculations.
