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Risk factors for stroke are well known in atrial fibrillation (AF) patients, while less is known on the effect of these factors on total mortality. Our aim was to study the impact of cardiovascular drug classes on mortality in AF patients treated in primary care. The study population was chosen based on patient data from 75 primary care centres in Sweden compiled in a database. Individuals diagnos
Background. This study aimed to evaluate Pediatric Appendicitis Score (PAS), diagnostic delay, and factors responsible for possible late diagnosis in children <4 years compared with older children who were operated on for suspected appendicitis. Method. 122 children, between 1 and 14 years, operated on with appendectomy for suspected appendicitis, were retrospectively analyzed. The cohort was divi
Diabetes Mellitus is a chronic disease characterized by the inability of the organism to autonomously regulate the blood glucose level due to insulin deficiency or resistance, leading to serious health damages. The therapy is essentially based on insulin injections and depends strongly on patient daily decisions, being mainly based upon empirical experience and rules of thumb. The development of a
A particle-based transported probability density function (PDF) method with a novel chemistry acceleration technique is developed in this work. The technique is based on the chemistry coordinate mapping (CCM) approach that was proposed in our previous works for accelerating direct numerical simulations (DNS) of partially premixed combustion. The method is first validated using Sandia flames D and
A coherent pulse generator for implementation in an impulse radio system is presented. It accurately transforms a 12.5 GHz square wave input signal to 33 ps long 60 GHz pulses. The wavelets are generated through direct conversion from base-band to 60 GHz by switching a negative differential conductance oscillator on and off. The slope of the input signal determines the phase, which is either I+ or
We develop the case for symmetrical assumptions in strategic management theory. Assumptional symmetry obtains when assumptions made about certain actors and their interactions in one of the application domains of a theory are also made about this set of actors and their interactions in other application domains of the theory. We argue that assumptional symmetry leads to theoretical advancement by
Purpose - This paper has three purposes. The first is to introduce the concept of fantasy, based on Lacanian pyschoanlysis, in order to link theoretically the role of narrative and affect in organizational strategies of control. The second is to use this concept to illuminate the fantasmatic as well as ideological character of so-called "market rationality." The third is to reveal three dominant f
Arterial stiffness is an independent risk factor for cardiovascular morbidity and can be assessed by applanation tonometry by measuring pulse wave velocity (PWV) and augmentation index (AIX) by pressure pulse wave analysis (PWA). As an inexpensive and operator independent alternative, photoelectric plethysmography (PPG) has been introduced with analysis of the digital volume pulse wave (DPA) and i
Popular Abstract in Swedish Diabetes mellitus är en endokrin sjukdom. Hos friska individer producerar beta och alpha cellerna i bukspottkörteln insulin och glukagon, de viktigaste hormonerna för att reglera blodglukos¬koncentrationen. Insulin utsöndras som svar på förhöjda blodglukosnivåer. Hormonet minskar glukosproduktion från levern och ökar glukosupptaget samt dess användning och lagring i fetType 2 Diabetes (T2D) is a multifactorial disease, which has made it difficult to resolve its pathophysiology. We investigated processes that could contribute to the development of T2D. In addition to well-known hallmarks of the disease, such as defective insulin secretion, insulin resistance and perturbed glucagon secretion, we aimed to find a possible role for CLOCK genes in the pathogenesis of
The semantic formalism reference attribute grammars (RAGs) allows graphs to be superimposed on abstract syntax trees. This paper investigates how RAGs can be used to model visual languages, with a case study of a control language that also has a textual syntax. The language contains blocks on which a total execution order is defined based on connections and layout information. One strength of RAGs
While the world's transport energy matrix is still strongly linked to limited and heavily polluting fossil fuels, new markets are appearing for the production and use of alternative transport fuels, such as liquid biofuels. Due to an interconnected global economy, such markets today are developing oil a global scale with actors looking to meet local as well as potential international demand. The a
This Letter presents evidence for the associated production of a W boson and a top quark using 2.05 fb(-1) of pp collision data at root s = 7 TeV accumulated with the ATLAS detector at the LHC. The analysis is based on the selection of the dileptonic final states with events featuring two isolated leptons, electron or muon, with significant transverse missing momentum and at least one jet. An appr
Denitrification is a critical process that can alleviate the effects of excessive nitrogen availability in aquatic ecosystems subject to eutrophication. An important part of denitrification occurs in benthic systems where bioturbation by meiofauna (invertebrates <1mm) and its effect on element cycling are still not well understood. Here we study the quantitative impact of meiofauna populations of
Continuous implementation of new operative methods for correction and stabilization of spinal deformities in young patients with AIS demands a detailed morphological analysis of the vertebral column. CT spine according to protocols available in daily clinical practice means high radiation dose to these young individuals. All examinations included in this thesis were performed on a 16-slice CT scan
S100A4 and S100A9 proteins have been described as playing roles in the control of tumor growth and metastasis. We show here that a chemical probe, oxyclozanide (OX), selected for inhibiting the interaction between S100A9 and the receptor for advanced glycation end-products (RAGE) interacts with both S100A9 and S100A4. Furthermore, we show that S100A9 and S100A4 interact with RAGE and TLR4; interac
Measurements based on a large number of red giant stars suggest a broad metallicity distribution function (MDF) for the Galactic bulge, centered on [Fe/H] approximate to -0.1. However, recently, a new opportunity emerged to utilize temporary flux amplification (by factors of similar to 100 or more) of faint dwarf stars in the Bulge which are gravitationally lensed, making them observable with high
