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Lung Metastases - Diagnostic, Prognostic and Molecular Aspects with Focus on Colorectal Cancer

In Sweden 4200 patients are diagnosed with lung cancer and 6500 patients with colorectal cancer (CRC) annually. The lungs are a common site for metastases. Immunohistochemistry (IHC) is a helpful aid in diagnostics of a pulmonary tumour. Selected patients with metastatic CRC undergo pulmonary metastasectomy and knowledge about which patients benefit from it is important. In this thesis IHC markers

Teammates That Are Destined to Become Rivals - A discourse analysis of team dynamics and performance in the pinnacle of motorsport

Purpose: The purpose of this thesis is to provide a deeper understanding of how team dynamics influence team performance, and thus team effectiveness, in an extreme environment. Methodology: In order to address the research question, a qualitative research study based on interpretive epistemology has been conducted. A discourse analysis is used with the aim to analyze the Formula 1 drivers’ use of

Litteraturlista Ett cirkulärt och biobaserat samhälle (MVES13) vårterminen 2022

Kursansvarig: Helena Hanson helena [dot] hanson [at] cec [dot] lu [dot] se (helena[dot]hanson[at]cec[dot]lu[dot]se)   Litteraturlista VT22 (PDF för utskrift 150 kB, ny flik)   All litteratur är tillgänglig online via Lunds universitets databaser. Litteraturlistan består av obligatorisk läsning och frivillig läsning. Litteratur tillkommer i relation till Uppgifter, Individuell litteraturöversikt oc

https://www.cec.lu.se/sv/litteraturlista-ett-cirkulart-och-biobaserat-samhalle-mves13-varterminen-2022 - 2026-05-31

Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4.

OBJECTIVE: Mapping coreceptor epitopes used by the prototypic R5 and X4 strains, HIV-1BaL and HIV-1IIIB, in comparison with epitopes involved in the activation and signaling induced by the natural ligands, RANTES and SDF-1beta. DESIGN: Receptor hybrids between CCR5 and CXCR4 were constructed. METHODS: Using single-overlap and extension PCR, increasing portions of CCR5 were replaced with correspond

Experiments and Large Eddy Simulation of Supersonic Combustion in the Small-Scale Flight Experiment

Supersonic combustion is a critical area of research for advancing high-speed flight technologies, particularly for the development of scramjet engines for hypersonic vehicles. This study employs Finite Rate Chemistry (FRC) Large Eddy Simulation (LES) together with different experimental techniques to study the supersonic flow and thermochemical processes in the Small Scale Flight Experiment (SSFE

Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

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The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN). To induce the nephropathy, we used two Streptococcus pyogenes strains of M4 and M60 serotypes which showed differential IgA-binding capacity me

GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

Production and Functional Characterization of Der p 1-Specific Human Recombinant IgE

Ny forskning bidrar till ökad förståelse av allergiska reaktioner Allergi har ökat dramatiskt under de senaste åren. Det är därför högst väsentligt att få ökad kunskap om hur beståndsdelarna i immunförsvaret hos allergiska personer samspelar. Förekomsten av allergi har kommit att öka dramatiskt under de senaste åren och har blivit ett betydande problem för folkhälsan. Allergi drabbar en så stor dThe prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic

TEDDY Årsrapport 2020

1 Årsrapport 2020 – TEDDY i Covid-19’s tid TEDDY - Omgivningsfaktorer för utveckling av autoimmun (typ 1) diabetes och celiaki hos barn 2 Innehållsförteckning 1. Vad har TEDDY kommit fram till om autoimmun (typ 1) diabetes under 2020? 2. Vad har TEDDY kommit fram till om celiaki (glutenintolerans) under 2020? 3. I vilket land är TEDDY-barnen mest aktiva? 4. TEDDY studiens pågående uppföljning. 5.

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/TEDDY%20%C3%85rsrapport%202020.pdf - 2026-06-01