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Purpose: Application of standardised and automated assessments of head computed tomography (CT) for neuroprognostication after out-of-hospital cardiac arrest. Methods: Prospective, international, multicentre, observational study within the Targeted Hypothermia versus Targeted Normothermia after out-of-hospital cardiac arrest (TTM2) trial. Routine CTs from adult unconscious patients obtained > 48 h

AIMS: Heart failure (HF) patients with anaemia tend to have a worse outcome, with increased hospitalization rates, decreased exercise tolerance, and higher mortality compared to those without anaemia. Limited research exists on the association between selenium deficiency and anaemia specifically in HF patients, despite previous findings of a correlation in different populations. The BIOSTAT-CHF st

Background: SARS-CoV-2, the causal agent of COVID-19, enters human cells using the ACE2 (angiotensin-converting enzyme 2) protein as a receptor. ACE2 is thus key to the infection and treatment of the coronavirus. ACE2 is highly expressed in the heart and respiratory and gastrointestinal tracts, playing important regulatory roles in the cardiovascular and other biological systems. However, the gene

Background: Disseminated tumour cells (DTCs) in the bone marrow of patients with breast cancer have been identified as an independent predictor of poor prognosis in patients with non-metastatic disease. This prospective study aimed to evaluate the presence and prognostic value of DTCs in the bone marrow of female patients with primary breast cancer. Methods: Between 1999 and 2003, bone marrow aspi

STUDY OBJECTIVE--The aim of the study was to investigate the receptor events that mediate the vascular effects of 5-hydroxytryptamine (5-HT) on human coronary arteries, since 5-HT has long been thought to play a role in coronary artery vasospasm. DESIGN--Recently available selective receptor agonists and antagonists were used to examine the 5-HT receptor subtypes present in human epicardial corona

(1) Thylakoids from spinach chloroplasts were phosphorylated, fragmented by sonication, and then fractionated by aqueous two-phase partitioning to yield membrane fragments, deriving from different structural domains of the membrane: grana, grana margins, grana core and stroma lamellae. The photochemical activities of PS I and PS II, located in the grana, and PS I and PS II, located in the stroma l

This thesis summarizes experimental work in which the powerful Ti:sapphire lasers at the High Power Laser Facility at the Lund Laser Centre have been employed to investigate laser-produced X-rays and relativistic channelling. These lasers produce short pulses, of the order of 50 fs, with energies ranging from 1 mJ to 1 J. Thus, the peak powers reach several terawatts and with the most powerful las

Studies of the long-lived anthropogenic radionuclides 99Tc, 237Np, 239Pu and 240Pu were performed in marine and terrestrial areas contaminated by different accidental and controlled releases of radioactive materials. The three main sources discussed in this thesis are nuclear weapons tests, nuclear reprocessing plants and the Chernobyl accident. Results are mainly based on measurements of environm

Enhanced biological phosphorus removal (EBPR) was studied in laboratory scale experiments as well as in a full scale EBPR process. The studies were focused on carbon source transformations, the use of nitrate as an electron acceptor and characterisation of the microflora. A continuous anaerobic/aerobic laboratory system was operated on synthetic wastewater with acetate as sole carbon source. An ef

Background: Moderately displaced two-fragment fractures of the radial head have been treated predominantly nonoperatively. Recently, however, open reduction and internal fixation has gradually gained interest, without clear evidence that initial nonoperative treatment leads to an unfavorable outcome. As a consequence, the purpose of the present study was to evaluate the long-term outcome after the

BACKGROUND: Iron deficiency may impair aerobic performance. This study aimed to determine whether treatment with intravenous iron (ferric carboxymaltose) would improve symptoms in patients who had heart failure, reduced left ventricular ejection fraction, and iron deficiency, either with or without anemia. METHODS: We enrolled 459 patients with chronic heart failure of New York Heart Association (

I investigated the bacterial utilization of terrestrially derived dissolved organic nitrogen (DON) in aquatic ecosystems, and assessed the potential role of river-born DON in marine eutrophication. To determine the bioavailability of DON, I developed a bioassay employing N-limited bacterial regrowth cultures, which were calibrated with additions of inorganic nitrogen. I found that between 2 and 72

This thesis deals with numerical simulations of the turbulent combustion process in Homogeneous Charge Compression Ignition (HCCI) engines. An accurate and computationally efficient Large Eddy Simulation (LES) model was developed and used throughout this thesis to investigate the development of in-cylinder turbulence, temperature stratification, onset of auto-ignition, and development of the react

Recent studies have indicated a decline in sperm number in the western world during the past 50 years, sperm concentration changing from 113 to 66 millions per mL. Furthermore, significant geographical differences in male reproductive function have been observed. In Finland, the sperm concentration was found to be substantially higher than in Denmark. In parallel, the incidence of testicular cance

Denna uppsats syftar till att dels redogöra för den nyklassiska skolan, samt utvecklingen av straffsystemet och kriminalpolitiken i Sverige fr.o.m. år 1965 t.o.m. år 2019, dels utreda vilket inflytande nyklassicismen har haft på utvecklingen av desamma. Undersökningen utgår från följande huvudfråge-ställning: är de senaste decenniernas straffrättsliga och kriminalpolitiska utveckling, med ny- och This essay aims to describe the neoclassical school, as well as the develop-ment of the criminal system and criminal policy in Sweden as from 1965 until 2019, and to also analyse if the neoclassical school has had any influ-ence on the development. The study is based on the following main issue: is the punitive development of the criminal system and criminal policy of the recent decades a result o

Barnets ställning i det svenska samhället har under de senaste århundradena utvecklats från en obetydlig människa till en individ som spelar en stor roll i människors liv. Denna utveckling är ett exempel på hur mänskliga relationer och sociala processer påverkar hur man ser på olika individer i samhället. Utvecklingen skulle också kunna ses som en bidragande orsak till varför vårdnadstvister har öIn the last centuries, the child´s position in society has evolved from being seen as an insignificant human being to an individual that plays an important role in people’s lives. This development is an example of how social processes and human relations play part in how we see different people in society. The custody disputes in Sweden has increased over the past years. The evolvement of the chil

Outsourcing and contract manufacturing have developed as effective business strategies for electronics manufacturing services in the recent years. Most Consumer Electronic brand firms do not actually make the consumer products they sell but hire contract manufacturers, mostly in the developing world. Asia is currently the major production base of mobile phones for instance, with China and ASEAN ac

Supernovor är några de kraftfullaste händelserna vi ser bland stjärnor. När stjärnor, mycket mer massiva än vår egen, bränner upp sitt bränsle tynar de inte bara bort, utan exploderar i vad vi kallar en Typ II supernova. På motsatta sidan kan lättare stjärnor i sina sista tillstånd som vita dvärgar fånga upp för mycket massa och explodera som Typ I supernovor. Båda dessa fallen har en stor betydelThe momentum and energy injection from supernovae is one of the main feedback modes, and is therefore key to the understanding of galaxy evolution and star formation. However, due to low resolution, large scale galaxy simulations often have issues with accurately modelling supernovae, and therefore rely on sub-grid models. This is especially true for the injected momentum, where capturing the mome

Kränkande särbehandling är ett begrepp som innefattar bland annat vuxenmobbning, trakasserier och sexuella trakasserier. Kränkande särbehandling genom mobbning regleras i svensk rätt främst genom arbetsmiljörätten. Arbetsmiljön ska enligt arbetsmiljölagen vara tillfredsställande och arbetsgivaren ska vidta alla åtgärder som behövs för att förebygga att arbetstagare drabbas av ohälsa. Det finns äveVictimization is a concept that mainly contains adult bullying, harassment and sexual harassment. Victimization through bullying is regulated in Swedish law primarily through the work environment legislation, since it is considered to be an organizational issue. The work environment shall according to the Swedish Work Environment Act be satisfactory and the employer shall take all the precautions