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Hans Ryde

Professor emeritus Contact details Email: hans [dot] ryde [at] fysik [dot] lu [dot] seOrganisation Particle and nuclear physics Service point: 14 WebpageHans Rydes profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllBookBook chapterEditor for a journalJournal articleOther Filter Chronicle of the discovery of the back-ben

https://www.particle-nuclear.lu.se/hans-ryde - 2026-05-26

New creatinine- and cystatin C-based equations to estimate GFR without race

Background: Current equations for estimated glomerular filtration rate (eGFR) that use serum creatinine or cystatin C incorporate age, sex, and race to estimate measured GFR. However, race in eGFR equations is a social and not a biologic construct.Methods: We developed new eGFR equations without race using data from two development data sets: 10 studies (8254 participants, 31.5% Black) for serum c

Hypoxia Generated by Avian Embryo Growth Induces the HIF-α Response and Critical Vascularization

Cancer research has transformed our view on cellular mechanisms for oxygen sensing. It has been documented that these mechanisms are important for maintaining animal tissues and life in environments where oxygen (O2) concentrations fluctuate. In adult animals, oxygen sensing is governed by the Hypoxia Inducible Factors (HIFs) that are stabilized at low oxygen concentrations (hypoxia). However, the

Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioural activation

Changes in extracellular levels of acetylcholine and choline in the hippocampal formation were measured using intracerebral microdialysis coupled to high performance liquid chromatography with post-column enzyme reaction and electrochemical detection. Various pharmacological and physiological manipulations were applied to awake unrestrained normal rats and rats subjected to a cholinergic denervati

Bioadaptor implant versus contemporary drug-eluting stent in percutaneous coronary interventions in Sweden (INFINITY-SWEDEHEART) : a single-blind, non-inferiority, registry-based, randomised controlled trial

Background: Persistent non-plateauing adverse event rates in patients who underwent percutaneous coronary intervention (PCI) remain a challenge. A bioadaptor is a novel implant that addresses this issue by restoring the haemodynamic modulation of the artery, allowing cyclic pulsatility, vasomotion, and adaptative remodelling, by unlocking and providing dynamic support to the artery. We aimed to as

Effects of nitrous oxide on human regional cerebral blood flow and isolated pial arteries

BACKGROUND: Results from previous studies on the effect of nitrous oxide (N2O) on the cerebral circulation are conflicting. Early reports claim N2O to have no effect whereas recent findings demonstrate a cerebral cortical vasodilatation during N2O inhalation, but the regional cerebral blood flow (CBF) in the subcortical structures is unknown. METHODS: Regional CBF was measured three-dimensionally

Sertoli and Germ Cells Within Atrophic Seminiferous Tubules of Men With Non-Obstructive Azoospermia

Background: Infertile men with non-obstructive azoospermia (NOA) have impaired spermatogenesis. Dilated and un-dilated atrophic seminiferous tubules are often present in the testes of these patients, with the highest likelihood of active spermatogenesis in the dilated tubules. Little is known about the un-dilated tubules, which in NOA patients constitute the majority. To advance therapeutic strate

Cervical or thoracic anastomosis after esophageal resection and gastric tube reconstruction - A prospective randomized triol comparing sutured neck anastomosis with stapled intrathorocic anastomosis

Objective: The purpose of the study was to compare in prospective randomized fashion a manually sutured esophagogastric anastomosis in the neck and a stapled in the chest after esophageal resection and gastric tube reconstruction. Summary Background Data: Despite the fact that all reconstructions after esophagectomy will result in a cervical or a thoracic anastomosis, controversy still exists as t

Evaluation of image quality and diagnostic accuracy in breast tomosynthesis. Comparison with digital mammography and estimates of radiation risk

Recent advances in the digital detector technology have paved the way for modalities such as two-dimensional digital mammography (DM) and three-dimensional breast tomosynthesis (BT). In this work, experimental studies were conducted to investigate the influence of reducing the average glandular dose (AGD) on detection of simulated lesions in DM and to compare the diagnostic accuracy of BT and DM.

The relationship between reduced renal function and cardiovascular disease

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Kardiovaskulär sjukdom (CVD) är ett i vårt samhälle växande problem där allt fler insjuknar i akuta hjärtinfarkter, stroke eller hjärtsvikt. Överlevnaden efter insjuknandet har förbättrats med åren med hjälp av nya mediciner och invasiva ingrepp såsom stentning av kranskärlen vid svår kärlkramp och direkt i det akuta skedet vid vissa tThis thesis examines the relationship between measures of renal function and cardiovascular disease (CVD) in patients with hypertension (the NORDIL study) and in the healthy population (Malmö Diet and Cancer Study, MDC) and whether antihypertensive treatment response and the risk of CVD is affected by genetic variation of a regulator of the renal amiloroide sensitive sodium channel (NORDIL). In st

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Mira is the perfect purity where the demonic of the master mason has no access. The craftsman’s wife is the embodiment of innocence, the heavenly depiction of mankind as opposed to demonic Manole. “Serenity” and “light” are words that repeatedly occur in her monologue thus suggesting the plenitudine of being she is about to conceive when she would be raising into the light her perfect precious, th

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical actiflty by glucose in wild-type and SUR1(-/-) mouse alpha-cells

Patch-clamp recordings and glucagon release measurements were combined to determine the role of plasma membrane ATP-sensitive K+ channels (K-ATP channels) in the control of glucagon secretion from mouse pancreatic alpha-cells. In wild-type mouse islets, glucose produced a concentration-dependent (half-maximal inhibitory concentration [IC50] = 2.5 mmol/l) reduction of glucagon release. Maximum inhi

Effects of clodronate on cortical and trabecular bone in ovariectomized rats on a low calcium diet

The aim of this study was to evaluate the contribution of a low calcium diet to the cortical and trabecular osteoporosis seen in ovariectomized rats after 7 weeks on a low calcium diet and to investigate the effects of the bisphosphonate clodronate on this development of osteoporosis. Thirty-six mature, female Wistar rats were randomized into four groups: Ovx-B (bisphosphonate) and Ovx-C (control)

Age-Related Changes in General and Sexual Health in Middle-Aged and Older Men: Results from the European Male Ageing Study (EMAS)

Introduction. Limited information is available concerning the general and sexual health status of European men. Aim. To investigate the age-related changes in general and sexual health in middle-aged and older men from different countries of the European Union. Methods. This is a cross-sectional multicenter survey performed on a sample of 3,369 community-dwelling men aged 40-79 years old (mean 60

The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. Inthe era of precision medicine, pin-pointing patient biological heterogeneity especially in relation to patient-specific immunemicroenvironment is a ne

Evaluation of in-situ technology performance and decision analysis by combining economic and environmental impact analysis for a case study

In the contemporary global context, the global focus on reducing environmental impacts in any formats has intensified. This study intends to assess the environmental impacts and life cycle costs associated with the A1-A5 stages (production and construction stages) of the Köping Port project and eight additional proposed scenarios. The Solidification/ Stabilization method along with the in-situ tec

The Alcyone CZT SPECT camera. Evaluation of performance using phantom measurement and Monte Carlo simulations

Background Coronary artery disease is one of the most common causes of death. A common cardiac examination is to give a visualization of the myocardial blood flow by injecting a radio pharmaceutical and detect the radiation with a camera. The camera has for decades been using thallium doped sodium iodide (NaI(Tl)) as the detector material. New detector materials have been developed because of the

Lead time analysis and reduction at Alfa Laval DC Lund

Alfa Laval DC Lund is both a spare part manufacturer and distributer. The spare parts that Alfa Laval DC Lund supplies are used for the heat transfer business unit of Alfa Laval. Sometimes orders need to be produced fast as customers may have breakdowns in production and sometime orders arrive months earlier than customers want to receive delivery as scheduled services occur at the customer. Probl