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The Early Carboniferous Mageroy dykes, northern Norway: palaeomagnetism and palaeogeography

Palaeomagnetic data from the 337 Ma Mageroy dykes (northern Norway) are of exceptionally high quality, and a positive contact test along with an existing regional result from the Silurian Honningsvag Igneous Suite attests to a primary Early Carboniferous magnetic signature. The palaeomagnetic pole (S 14.8degrees, E320.1degrees, dp/dm = 4.4/8.6degrees) is the first Early Carboniferous pole from Bal

Pressurized hot water extraction of insecticides from process dust - Comparison with supercritical fluid extraction

Pressurized hot liquid water and steam were used to investigate the possibilities of extracting insecticides (carbofuran, carbosulfan, and imidacloprid) from contaminated process dust remaining from seed-pellet production. Extraction temperature was the most important parameter in influencing the extraction efficiency and rate of extraction, while varying the pressure had no profound effect. A cle

Beta-estradiol effect on erythrocyte aggregation--a controlled in vitro study

The purpose of this in vitro study was to assess the effect of 17beta-estradiol on hemorheologic parameters, namely on erythrocyte aggregation and deformability and membrane fluidity.Blood samples from 65 women (aged 57 +/- 4 years) undergoing postmenopausal hormone replacement therapy were obtained and were incubated for 5 min in absence and presence of 17beta-estradiol 10(-5) M. The measured par

Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1

Tissue factor (TF) triggers upstream coagulation signaling via the activation of protease-activated receptors (PARs) of relevance for inflammation and angiogenesis. TF pathway inhibitor 1 (TFPI-1) is the physiologic inhibitor of TF-initiated coagulation, but its role in regulating TF signaling is poorly understood. Here, we demonstrate that endogenous, endothelial cell-expressed TFPI-1 controls TF

Adaptation of soil microbial communities to temperature: comparison of fungi and bacteria in a laboratory experiment

Temperature not only has direct effects on microbial activity, but can also affect activity indirectly by changing the temperature dependency of the community. This would result in communities performing better over time in response to increased temperatures. We have for the first time studied the effect of soil temperature (5-50 degrees C) on the community adaptation of both bacterial (leucine in

Environmental exposure to lead and arsenic among children living near a glassworks

Concentrations of lead (Pb) in blood (B-Pb, geometric mean 34.6 micrograms l-1, n = 127) and inorganic arsenic (As) and its metabolites in urine (U-As, mean 5.1 micrograms/g creatinine, n = 35) did not differ between children living in a village close to a glassworks emitting both Pb and As and children living in a reference area. There was no significant effect on B-Pb and U-As related to parents

Study of the solar wind coupling to the time difference horizontal geomagnetic field

The local ground geomagnetic field fluctuations (AB) are dominated by high frequencies and 83% of the power is located at periods of 32 min or less. By forming 10-min root-mean-square (RMS) of A B a major part of this variation is captured. Using measured geomagnetic induced currents (GIC), from a power grid transformer in Southern Sweden, it is shown that the 10-min standard deviation GIC may be

Long-distance transports of newborn infants with congenital heart disease

Little has been published about specific problems that may occur during long-distance transports of newborn cardiac patients. During a 4-year period after centralization of pediatric heart surgery in Sweden, 286 transports were prospectively investigated. A majority (77.3%) of the transports were carried out by nonspecialized teams. Ten severe adverse events, including the death of 1 infant, occur

Rapid one-step whole blood C-reactive protein magnetic permeability immunoassay with monoclonal antibody conjugated nanoparticles as superparamagnetic labels and enhanced sedimentation

A rapid (5.5 min) one-step whole blood C-reactive protein (CRP) magnetic permeability immunoassay utilizing monoclonal antibody conjugated dextran iron oxide nanoparticles (70 nm) as superparamagnetic labels and mixed fractions (1:1 ratio of 15-40 and 60 mu m) of polyclonal anti-CRP conjugated silica microparticles for enhanced sedimentation is described. In this one-step assay procedure, a whole

Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders

Synaptogenesis, the formation of functional synapses, is a crucial step for the development of the central nervous system. Among the genes involved in this process are cell adhesion molecules, such as protocadherins and neuroligins, which are essential factors for the identification of the appropriate partner cell and the formation of synapses. In this work, we studied the expression and the genet

Unexpected early extinction of the European pond turtle (Emys orbicularis) in Sweden and climatic impact on its Holocene range

Using ancient DNA sequences of subfossil European pond turtles (Emys orbicularis) from Britain, Central and North Europe and accelerator mass spectrometry radiocarbon dating for turtle remains from most Swedish sites, we provide evidence for a Holocene range expansion of the pond turtle from the southeastern Balkans into Britain, Central Europe and Scandinavia, according to the 'grasshopper patter

Determinants of local ant (Hymenoptera: Formicidae) species richness and activity density across Europe

1. Species richness is influenced by local habitat features and large-scale climatic gradients. Usually, both influences are studied in isolation because of the divergent spatial scales at which they occur. Here, we compared the influence of large-scale climate and local habitat type on European ants using a continent-wide, standardised sampling programme. 2. We investigated species richness and a

Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.

The procoagulant function of activated factor V (FVa) is inhibited by activated protein C (APC) through proteolytic cleavages at Arg(306), Arg(506), and Arg(679). The effect of APC is potentiated by negatively charged phospholipid membranes and the APC cofactor protein S. Protein S has been reported to selectively stimulate cleavage at Arg(306), an effect hypothesized to be related to reorientatio

Thoracic gas volume measurements in paralyzed mice

We have previously measured thoracic gas volume (V-TG) in spontaneously breathing mice using a whole body plethysmograph and have now extended our technique to allow for V-TG measurements during paralysis. BALB/c mice were anesthetized and placed in a body-box and ventilated via a tracheostomy cannula through the box wall. Box pressure (P-b) and tracheal pressure (P-ao) were measured during sponta

Seeing red: morph-specific contest success, and survival rates, in a colour-polymorphic agamid lizard

Red coloration in multicoloured or polymorphic species has been associated with dominance in a number of case studies, including probability of winning in human sports. However, it is not clear at what stage during ontogeny the association between red and the probability of winning contests occurs (or being perceived as more threatening by a contradistinct rival), for example, at conception, early

Stimulation of vascular protein synthesis by activation of oestrogen receptor beta

The objective of this study was to investigate the effects of oestrogen receptor (ER) beta activation on vascular protein synthesis and protein expression. Nuclear immunoreactivity towards ER beta was observed abundantly in vascular smooth muscle and endothelial cells of mouse aorta. No ER alpha-positive cell nuclei were observed. In aorta from ovariectomized mice, treatment with the selective ER

Effects of propofol on substance P-induced relaxation in isolated human omental arteries and veins

To elucidate if an effect of propofol on endothelium-dependent relaxation could contribute to propofol-induced vasodilation, smooth muscle relaxation of isolated human omental artery and vein segments precontracted by endothelin-1 were measured. Substance P induced a concentration-dependent relaxation (mean +/- SEM) in both artery (63 +/-8.4% of precontraction, n = 9) and vein (60+/-11%, n = 7). T