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A group of 38 male workers at a secondary smelter (period of employment 2-35 years; median 10 years) was divided into two subgroups depending on bone-lead concentration, arranged as 19 matched pairs according to age, education and job level. The median concentrations for finger-bone lead (Bone-Pb) were 16 vs. 32 μg/g; for current blood-lead (B-Pb), 1.6 vs. 1.8 μmol/l; for retrospective peak blood-
PURPOSE: We have recently identified homeostatic alterations in the circulating T cells of patients with age-related macular degeneration (AMD). In cultures of retinal pigment epithelial cells, we have demonstrated that T-cell-derived cytokines induced the upregulation of complement, chemokines and other proteins implicated in AMD pathogenesis. The purpose of this study was to test whether increas
We use cosmological hydrodynamic zoom simulations to study the neutral gas distributionin and around galaxies that gives rise to high column density HILyαabsorption (dampedLyαsystems (DLAs) and sub-DLAs) in background quasar spectra. Such simulations oftensacrifice numerical resolution for volume that affects the lower density galaxy halo gas,and simulations have difficulties reproduci
Radiological evaluation of incidentally detected lung nodules on computed tomography (CT) influences management. We assessed international radiological variation in 1) pulmonary nodule characterisation; 2) hypothetical guideline-derived management; and 3) radiologists' management recommendations.107 radiologists from 25 countries evaluated 69 CT-detected nodules, recording: 1) first-choice composi
It is hypothesized that insulin resistance and related metabolic factors may influence breast cancer risk, however the epidemiological evidence remains inconclusive. We conducted a case-control study nested in a prospective cohort in Northern Sweden, to clarify the associations of body mass index (BMI), leptin, adiponectin, C-peptide, and glycated haemoglobin (HbA1c) with breast cancer risk. We al
1. In the rat hepatic artery, the SK(Ca) inhibitors UCL 1684 (300 nM) completely blocked, and scyllatoxin (1 μM) and d-tubocurarine (100 μM) partially inhibited EDHF relaxations when each of them was combined with charybdotoxin (300 nM). 2. The IK(Ca) inhibitors clotrimazole (3 μM) and 2-chlorophenyl-bisphenyl-methanol (3 μM) strongly depressed EDHF relaxations when each of them was combined with
Soil erosion by water represents a serious threat to the natural and human environment in Mediterranean countries, including Lebanon, which represents a good case study. This research deals with how to use Geographic Information Systems (GIS), remote sensing, and, more specifically, structural classification techniques and decision-tree modeling to map erosion risks and design priority management
Spatial distribution information on population density is essential for understanding urban dynamics. In recent decades, remote sensing techniques have often been applied to assess population density, particularly night-time light data (NTL). However, such attempts have resulted in mapped population density at coarse/medium resolution, which often limits the applicability of such data for fine-sca
Neuronal protein synthesis is severely depressed following stress such as heat-shock, hypoxia, and hypoglycemia. Following reversible cerebral ischemia, protein synthesis is transiently inhibited in ischemia-resistant areas, but persistently depressed in vulnerable brain regions. Eukaryotic initiation factor 2 (elF-2) activity, that is, the formation of the ternary complex elF-2 · GTP · initiator
Glutamatergic transmission is an important factor in the development of neuronal death following transient cerebral ischemia. In this investigation the effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on neuronal damage were studied in rats exposed to 10 min of transient cerebral ischemia induced by bilateral common carotid occlusion combined with hypotension. The animals w
BackgroundOrgan donation guidelines recommend a “clear” conventional bedside chest radiograph before lung transplantation despite only moderate accuracy for cardiopulmonary abnormalities.PurposeTo evaluate the influence of donor image interpretation on lung transplantation outcome in recipients by following early and late complications, one-year survival, and to correlate imaging findings and bloo
We analyzed seasonal flu vaccination rates among the Italian population suffering from Chronic Obstructive Pulmonary Disease (COPD) in order to identify socio-demographic and clinical determinants for vaccination. We used data from the survey "Health and health care use in Italy", which interviewed 5,935 persons (age 15 - 102 years) suffering from COPD in the period 2004-2005. For each respondent,
Five hundred thirty-two cases of slipped capital femoral epiphysis (physiolysis colli femoris - PCF) treated at three orthopedic departments in southern Sweden between 1910 and 1982 were used for epidemiologic studies. Three hundred twenty-five cases came from a well-defined area and were used for incidence analyses. During the whole period of investigation, the disease was more common in men than
Interpretation of numeric automated threshold visual field results is often difficult. A large amount of data is obtained for every single field tested. Various approaches to summarize this data have been suggested, most commonly the mean and standard deviation of departures from age-corrected normal threshold values. These visual field indices differ substantially from subjective field interpreta
This report presents the sixth version of the European Grassland Butterfly Indicator, one of the EU biodiversity indicators of the European Environment Agency.The indicator is based on more than 9200 transects in national Butterfly Monitoring Schemes covering 22 countries across Europe, most of them active in the European Union. In 2015, counts were made in more than 4500 transects.Butterflies rep
In a gas turbine engine, the low pressure turbine (LPT) and the outlet guide vane (OGV) part are connected in the rear part. The outlet nozzle is designed as a contracted part to increase the ejection velocity and a pocket cavity (PC) is formed at this location. In this research work, the effects of the locations of the PC on the downstream endwall with a symmetrical vane (SV) are investigated and
Assessment of bilingual children in only one language fails to acknowledge their distributed linguistic competence and has been shown to overidentify language disorder in bilingual populations. However, other factors, sometimes associated with bilingualism, may also contribute to low results in language assessments. Our aim was to examine the impact of these factors on language abilities. We used
HYPOTHESIS: The clinical and physiological features of patients with short segments of columnar-lined esophagus (CLE) with and without intestinal metaplasia (IM) are distinct.DESIGN: Retrospective case series.SETTING: University tertiary referral center.PATIENTS: Sixty-five consecutive patients with a 2-cm or shorter length of endoscopically visible CLE.INTERVENTIONS: The type of CLE and the prese
