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Background and Aims: It is unclear whether obesity is associated with the development of inflammatory bowel disease despite compelling data from basic science studies. We therefore examined the association between obesity and risk of Crohn's disease (CD) and ulcerative colitis (UC). Methods: We conducted pooled analyses of 5 prospective cohorts with validated anthropometric measurements for body m

Background and purpose — Strenuous efforts to minimize postoperative infection rates have been made, including the Swedish nationwide initiative Prosthesis Related Infections Shall be Stopped (PRISS). This study calculated the incidence rate of periprosthetic joint infection (PJI) following primary total knee arthroplasty (TKA) before and after PRISS. Patients and methods — All 45,438 primary TKAs

Pregnancy is a valuable model to study the association between DNA methylation and several cardiometabolic traits, due to its direct potential to influence mother's and child's health. Epigenetics in Pregnancy (EPIPREG) is a population-based sample with the aim to study associations between DNA-methylation in pregnancy and cardiometabolic traits in South Asian and European pregnant women and their

Aim: Previous studies evaluating the relationship between sex and post-resuscitation care and outcomes following out-of-hospital cardiac arrest (OHCA) are conflicting. We investigated the association between sex and outcomes as well as neurodiagnostic testing in a prospective multicenter international registry of patients admitted to intensive care units following OHCA. Methods: OHCA survivors enr

RelA/SpoT Homologue (RSH) proteins, named for their sequence similarity to the RelA and SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize and/or hydrolyze the alarmone ppGpp, activator of the "stringent" response and regulator of cellular metabolism. The classical "long" RSHs Rel, RelA and SpoT with the ppGpp hydrolase, synthetase, TGS and ACT domain architecture

OBJECTIVES: Degenerative mitral valve disease is the most common indication for mitral valve repair in the Western world. The aim of this study was to study the long term outcome of mitral valve repair for degenerative mitral valve regurgitation in Iceland. MATERIAL AND METHODS: A retrospective study of 101 consecutive mitral valve repair patients (average age 57.7 years, 80.2% male) operated in I

Background: The outcome for diffuse large B-cell lymphoma (DLBCL) patients has improved with the immunochemotherapy combination R-CHOP. An increased rate of heart failure is well documented following this treatment, whereas incidence and outcome of other cardiac complications, for example myocardial infarction, are less well known. Method: We identified 3548 curatively treated DLBCL patients in Sw

INTRODUCTION: Informal carers in paid employment-working carers (WKCs)-have complex support needs. However, little is known about WKCs' pattern of informal care provision, the support they receive, the impact providing care has on their employment, and how these vary between male and female WKCs. This study describes the pattern of informal care provision and received support among Swedish WKCs.RE

Research show that human trafficking is one of the fastest growing criminal industries today, after narcotics and illegal arms trade (The Polaris Project 2014). The most common victims of human trafficking are stated to be women and children (UNODC 2012). According to the UNICEF (2007), 1,2 million children are estimated to be exposed to trafficking for various exploitative purposes every year aro

Examensarbetets titel: Dina åsikter spelar roll - En kvalitativ studie av konsumentrecensioner online Seminariedatum: 2015-01-15 Ämne/kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 HP Författare: Jens Boström, Denis Maliqaj och Bobo Tiger Handledare: Clara Gustafsson Fem nyckelord: Konsumentrecensioner online, e-WOM, CCT, Gemenskaper, Informationsdelning vid konsumtion. Syfte:Title: Your opinions matter - A qualitative study of consumer reviews online. Seminar date: 2015-01-15 Course: FEKH29, Degree Project in Marketing Undergraduate Level, 15HP Authors: Jens Boström, Denis Maliqaj and Bobo Tiger Advisor: Clara Gustafsson Key words: Online consumer reviews, e-WOM, CCT, Online Communities, Information sharing regarding consumption. Purpose: The purpose of this stu

Introduction: Tuberculosis (TB) is the most common opportunistic infection (OI) and cause of death in people living with HIV/AIDS (PLHIV), even in settings with access to antiretroviral therapy (ART). This study aims to determine factors associated with adverse outcome of TB treatment in PLHIV. Materials and Method: The study was retrospective cohort study which includes 958 individuals aged ≥15 y

The present thesis, adopting the ecology of language as its conceptual orientation as well as employing linguistic landscape as its methodological tool to collect and analyze data, firstly aims at investigating (1) how the four official languages of Singapore namely Malay, (Mandarin) Chinese, Tamil, and English have been deployed on signs by three different social actors, i.e., the Singaporean gov

Formulering av läkemedel kräver att man tar tag i ett flertal problem för att optimera effektiviteten. All former av formuleringar har sina egna utmaningar som vetenskapsmän och företag försöker lösa. Till exempel, leverns nedbrytning av läkemedlet, det så kallade första-passage-metabolismen, minskar koncentrationen av den aktiva substansen och, i värsta fall, förändrar den till en giftig form. DeThe aim of this master thesis is to provide an indication of the suitability, or otherwise usage, of spray-drying for production of powder aimed for inhalation formulation and comparing the characteristics of the product, with and without lipids. Lipids have a proven effect of delaying release of active drug substances in the cardiovascular system and pulmonary systemic delivery has a number of ad

The risk for drinking water scarcity does not only concern developing countries and arid places. In its 2023 report, the Intergovernmental Panel on Climate Change has identified water scarcity as one of Europe’s key risks out of five in the foreseeable future. Sweden experiences water shortages more and more frequently during summer, and the need to protect groundwater resources is imperative. In

This degree project aimed to produce a standardized food product enriched with 14g polar lipids (PL) and compare its effects on glycemic response and appetite sensations both acutely and following a second meal in healthy individuals. In order to elucidate the viability of enriching a prebaked product with polar lipids researchers spent multiple weeks assessing variations in recipe, cook time, coo

Today cities are the result of centuries of history and human development, accelerated during the past 100 years. Post-industrialization, modernism’s top-down city planning approach, and the prioritisation of motor vehicle design over humans resulted in more people moving to cities, more space needed to allocate new vehicles, expansion over rural areas, and exponential pollution growth. Thus, huma