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Popular science summary: NADase – a way to avoid immune system activation? Streptococcus pyogenes (S. pyogenes) are bacteria that cause many different kinds of diseases in humans, for example strep throat, scarlet fever and necrotizing fasciitis, the ”flesh-eating disease”. An infection with this type of bacteria can also lead to heart and kidney damage, thought to be caused by our immune system
Purpose The purpose of the study has been to estimate the size of the market segment, identify strategically important customers and interesting parts of the segment as well as create an understanding of customer needs when buying furniture for their businesses where care and healthcare is practised. Method The study has been of an exploratory nature with a case study approach since the purpose of
Title: Retro Rewind - Unveiling the Power of Nostalgia in Fashion Retro Branding and Its Influence on the Brand Perception of Young Consumers Date of the Seminar: 31 June 2024 Course: BUSN39 Degree Project in Global Marketing Authors: Juan Bibudis and Tim Mårtensson Supervisor: Tommy Shih Examiner: Mats Urde Keywords: Nostalgia, identity, perception, Consumer Culture Theory (CCT), possessions, con
The thesis focuses on optimizing microfluidic methodology to create lipid sponge phase nanoparticles (L3NPs) for myoglobin encapsulation, while investigating buffer and pH effect on particle characteristics. Traditional LNP production methods like ultrasonication are time consuming and requires large material quantities. Microfluidic techniques offer a more precise and cost effective alternative b
Narcolepsy is a lifelong sleep disorder related to hypocretin deficiency resulting from a specific loss of hypocretin-producing neurons in the lateral hypothalamic area. The disease is thought to be autoimmune due to a strong association with HLA-DQB1*06:02. In 2009 the World Health Organization (WHO) declared the H1N1 2009 flu pandemic (A/H1N1PDM09). In response to this, the Swedish vaccination c
Introduction Metabolic dysfunction is one of the hallmarks of sepsis yet little is known about local changes in key organs such as the heart. The aim of this study was to compare myocardial metabolic changes by direct measurements of substrates, such as glucose, lactate and pyruvate, using microdialysis (MD) in in-vivo porcine endotoxemic and hemorrhagic shock. To assess whether these changes were
Background: Global stroke epidemiology is changing rapidly. Although age-standardized rates of stroke mortality have decreased worldwide in the past 2 decades, the absolute numbers of people who have a stroke every year, and live with the consequences of stroke or die from their stroke, are increasing. Regular updates on the current level of stroke burden are important for advancing our knowledge
Organic acids, central to terrestrial carbon metabolism and atmospheric photochemistry, are ubiquitous in the troposphere in the gas, particle, and aqueous phases. As the dominant organic acids in the atmosphere, formic acid (FA, HCOOH) and acetic acid (AA, CH3COOH) control precipitation acidity in remote regions and may represent a critical link between the terrestrial carbon and water cycles by
Introduction: We have previously shown that a tag single nucleotide polymorphism (rs10235235), which maps to the CYP3A locus (7q22.1), was associated with a reduction in premenopausal urinary estrone glucuronide levels and a modest reduction in risk of breast cancer in women age <= 50 years. Methods: We further investigated the association of rs10235235 with breast cancer risk in a large case cont
IMPORTANCE The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs over 2 years. OBJECTIVE To investigate whether radiological superiority translates into be
Investigating the influence of the tidal regime on harbour porpoise Phocoena phocoena distribution in Mount’s Bay, Cornwall Abstract Unintentional by-catch in fishing gear is a significant cause of mortality of harbour porpoises in UK waters. Understanding the spatial distribution of harbour porpoises at fine scales and how this changes over time is essential when trying to understand where thes
The interactions between airway epithelial cells (AECs) and dendritic cells (DCs) play an important role in the sensitization towards airborne allergens. Not much is known about the underlying mechanisms and novel in vitro approaches are needed, which include the different involved cell types in order to investigate what happens at the molecular level during sensitization. In this project, one aim
Populärvetenskaplig sammanfattning: Examensarbetet har gått ut på att med hjälp av satellitbilder göra markanvändningsdata för att förbättra en modell som beräknar vart de luftburna föroreningarna tar vägen. Föroreningarna svavel och kväve deponeras med olika hastighet över olika marktyper, därför vill man använda sig av markanvändningsdata i modellerna. Svavelutsläppen har ökat dramatiskt under Sulphur emissions during the last century has led to major acidification of the environment. The acidity of soil and water is a threat to health and economic interests of man, e.g. the food and paper/wood production in the agricultural and silvicultural industries. The Black Triangle region suffers from severe damage caused by acidification and actions to decrease the acid rain over fields and for
Syftet med denna studie är att utreda möjligheterna för Öresundskraft AB att utvinna marin förnyelsebar energi från norra Öresund. Studien genomförs i två delar där Öresunds fysikaliska egenskaper samt marina krafttekniker kartläggs i den första för att sedan analysera den möjliga miljöpåverkan från de alternativen som kan vara intressanta i Öresund. De marina energitekniker som studerades var OTEThe purpose of this study is to determine the possibilities for Öresundskraft AB to derive marine renewable energy from northern Öresund, the sound between Sweden and Denmark. The physical properties of the sound, such as temperature, current speed, wave height, salinity gradients, bathymetry, are researched as well as which technologies are present in the current marine renewable energy market. T
Området som undersöktes i denna studie ligger i västra delen av Hamrångesynklinalen. I studien har bergarter, bergartsgränser och strukturer karterats i fält. Tunnslip undersöktes med optisk mikroskopi i avseende på petrografi och förekomst av mikrostrukturer. Flera av tunnslipen har punkträknats för bergartsklassificering. Några bergarter har Rietveldanalyserats för närmare bestämning av mineralsThe studied area is located in the western part of the Hamrånge syncline. In this area, the rocks, contacts and structures were mapped . Thinsections were investigated regarding petrography and microstructures, and representative thinsections were pointcounted. Three samples were selected for Rietveld analysis to receive the chemical compositions. Minerals from both the syncline and the area outsi
