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Genome-Wide DNA Methylation Profiling of Chronic Lymphocytic Leukemia Subsets Carrying Stereotyped B Cell Receptors

In recent years, subsets of chronic lymphocytic leukemia (CLL) patients carrying quasi-identical or stereotyped B cell receptors (BcRs) have been identified that share clinicobiological features and disease outcome. While these stereotyped subsets show distinct gene expression and genomic profiles, the DNA methylation landscape remains largely unexplored. By applying high-resolution 450K methylati

Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2) : a 56-week, double-blind, phase 3a, randomised trial

Background Semaglutide is a novel glucagon-like peptide-1 (GLP-1) analogue, suitable for once-weekly subcutaneous administration, in development for treatment of type 2 diabetes. We assessed the efficacy and safety of semaglutide versus the dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin in patients with type 2 diabetes inadequately controlled on metformin, thiazolidinediones, or both. Method

Förlikning och medling - sett ur svenskt och norskt perspektiv

Det finns flera fördelar med att en tvist avgörs genom förlikning istället för genom dom. Genom att tvisten kan avgöras snabbare, har förlikningen fördelar genom att den kan spara tid och därigenom kostnader. Detta är fördelar som gynnar både parterna ifråga och rättssystemet i sin helhet. Förlikning kan även innebära den fördelen för parterna att deras relation skadas mindre om de frivilligt komm

Glaucoma Diagnostics

Popular Abstract in Swedish Bakgrund Den kroniska ögonsjukdomen grön starr (glaukom) skadar ögats synnerv och påverkar den perifera synen (synfältet) hos de som drabbas. I västvärlden är grön starr den näst vanligaste orsaken till blindhet enligt Världshälsoorganisationen WHO. I Sverige räknar man med att cirka 70 000 personer över 70 år har grön starr, men att endast hälften av dessa är kända förThis thesis addresses several aspects of glaucoma diagnostics from both a clinical and a screening perspective. New instruments for diagnosing glaucoma have been developed over the past years, but little information is available regarding their performance as screening methods and their usefulness in ordinary clinical practice. Purpose of the research underlying this thesis The objectives of the

Competition for forest resources between the biofuels and the forest industry in Sweden

The aim of this project was to determine the consequences of the large-scale introduction of wood-based biofuels in the road transport sector. Therefore a model has been developed to project the demand for wood in Sweden in the period from 2007 to 2050. The wood-using sectors that were taken into account are: the sawmill industry; the paper and pulp industry, which was split in three: integrated c

The consolidated European synthesis of CO2 emissions and removals for the European Union and United Kingdom : 1990-2020

Quantification of land surface-atmosphere fluxes of carbon dioxide (CO2) and their trends and uncertainties is essential for monitoring progress of the EU27+UK bloc as it strives to meet ambitious targets determined by both international agreements and internal regulation. This study provides a consolidated synthesis of fossil sources (CO2 fossil) and natural (including formally managed ecosystems

Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children

Background: Respiratory viruses are the leading cause of lower respiratory tract infection (LRTI) and hospitalisation in infants and young children. Respiratory syncytial virus (RSV) is the main infectious agent in this population. Palivizumab is administered intramuscularly every month during five months in the first RSV season to prevent serious RSV LRTI in children. Given its high cost, it is e

Regulation of HPV16 Early Gene Expression

Human papillomavirus type 16 (HPV16) is the most common high-risk type and isassociated with more than 50% cervical cancer cases as well as a number of headand neck cancer cases. The life cycle of HPV16 is strictly linked to celldifferentiation in the squamous epithelium with expression of the HPV16 earlygenes. The oncoproteins E6 and E7 are essential for preventing apoptosis andinducing prolifera

Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration : a retrospective diagnostic performance study

Background: Plasma tau phosphorylated at threonine 217 (p-tau217) and plasma tau phosphorylated at threonine 181 (p-tau181) are associated with Alzheimer's disease tau pathology. We compared the diagnostic value of both biomarkers in cognitively unimpaired participants and patients with a clinical diagnosis of mild cognitive impairment, Alzheimer's disease syndromes, or frontotemporal lobar degene

Applying coagulation, flocculation and discfiltration in tertiary treatment

Reducing eutrophication in our surface waters caused by nutrient overload is of importance in order to ensure an environment in ecological balance for future generations. Municipal wastewater treatment plants are the main point source of nutrients emissions. Effluent water can be treated by introducing a final advanced treatment step to existing wastewater treatment plants. The present thesis conc

Academic-qualifications-portfolio-at-Lund-University

Academic qualifications portfolio at Lund University Page 1 of 24 GUIDELINES Attachment Reg. No. PE 2013/34 Date 2013-01-24 Academic qualifications portfolio at Lund University As a sub-project of PUPA – Personal development and professional working conditions – a project group composed of representatives of the academic appointments boards of five of the University’s faculties, together with LU H

https://www.staff.lu.se/sites/staff.lu.se/files/2023-02/Academic-qualifications-portfolio-at-Lund-University.pdf - 2026-05-28

Oki-publikationer service management no 1 april 2011

RESEARCH IN SERVICE STUDIES LUND UNIVERSITY, Campus Helsingborg Working paper No 1, April 2011 The Department of Service Management From “A farewell to landfill” to “A farewell to wastefulness” – Societal narratives, socio-materiality and organizations Hervé Corvellec & Johan Hultman From “A farewell to landfill” to “A farewell to wastefulness” – Societal narratives, socio-materiality and organiza

https://www.ses.lu.se/sites/ses.lu.se/files/oki-publikationer_service_management_no_1_april_2011.pdf - 2026-05-28

Protein structures

Protein structures | Immunotechnology Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiab

https://www.immun.lth.se/research/principal-investigators/mats-ohlin/research/protein-structures/ - 2026-05-25

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Why phrases probe FREDRIK HEINAT (L UND UNIVERSITY ) Abstract This paper looks at the arguments for the stipulation that only heads are probes. Three areas where there traditionally have been made a difference between heads and phrases are examined. These areas are, phrase structure, movement, and selection. The strongest argument against probing phrases seems to be selection. Furthermore, Hallman

https://www.sol.lu.se/fileadmin/media/forskning/workingpapers/engelska/vol05/heinat-wp05.pdf - 2026-05-25

Current Lise Meitner professors

Current Lise Meitner professors | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These

https://www.lth.se/english/working-at-lth/lise-meitner-professorship/current-lise-meitner-professors/ - 2026-05-25

“Follow your intuition. That's my advice"

“Follow your intuition. That's my advice" Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not stor

https://www.lth.se/english/article/anne-lhuillier-awarded-nobel-prize-in-physics/ - 2026-05-26

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Nummer 1 • 2008 är vi bäst i landet? • stor studentökning i år • trådlöst nätverk på campus Studier som rockar fett... Studier som rockar fett... Wherever the road leads. Shooting whitewater. Fishing deepwater. Cycling the back roads. Skiing a mountain pass. Speed boating with your pals. Camping with the kids. Going where it moves you. Doing what you love. At the ends of the earth – or just around

https://www.lth.se/fileadmin/lth/omlth/kommunikation/lthnytt/LTH-nytt_1_08_.pdf - 2026-05-26

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Nummer 2 • 2007Nummer 2 • 2007 Framtidens campus Framtidens campus N Y R E K T O R S D U O • P O RTA L E N F Ö R M J U K VA R A • P Å E TA N O L F R O N T E N M Y C K E T N Y T T LT H - n y t t n u m m e r 2 • 2 0 0 72 Driven by sense Cybercom Group är ett högteknologiskt konsultföretag som erbjuder global sourcing för end-to-end-lösningar. Koncernen har etablerat sig som en leverantör i världskla

https://www.lth.se/fileadmin/lth/omlth/kommunikation/lthnytt/lthn07_2.pdf - 2026-05-26

On the Swedish så-construction

On the Swedish så-construction Working Papers in Scandinavian Syntax 85, 37-63 The Swedish så-construction, a new point of departure Jackie Nordström Centre for Languages and Literature, Lund University ABSTRACT The following article treats the Swedish så-construction (involving the so-called “adjunctive” så). The så-construction consists of a first element, which is typically an adjunct, followed

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/WPSS_85_Nordstroem.pdf - 2026-05-25