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Background: The carba mix is used to screen rubber chemical allergy and consists of three rubber sensitising chemicals: 1% (w/w) zinc diethyldithiocarbamate (ZDEC), 1% (w/w) zinc dibutyldithiocarbamate (ZDBC) and 1% (w/w) 1,3-diphenylguanidine (DPG), all in petrolatum. However, carba mix patch test results can be difficult to interpret, which may be linked to so-called ‘cocktail’ effects. Objectiv
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Evolutionary changes in populations of microbes, such as microalgae, cannot be traced using conventional metabarcoding loci as they lack intraspecific resolution. Consequently, selection and competition processes among strains of the same species cannot be resolved without elaborate isolation, culturing, and genotyping efforts. Bamboozle, a new bioinformatic tool introduced here, scans the entire
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As immersive technologies expand in education, a gap persists between teachers’ familiarity with virtual reality (VR) tools and effective pedagogical use. This study designed, implemented, and evaluated a 60-h VR Trainer Training Program using Educational Design Research (EDR) and the Taba-Tyler curriculum model. Sixteen teachers participated in a needs analysis, followed by 42 in-service teachers
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The aim of this thesis is to investigate the effectiveness of using specific alarms for each hazardversus the effectiveness of using a single alarm for all hazards in multi-hazard facilities. Theresearch was conducted by disseminating online questionnaires containing audio files of differentalarms to occupants of multi-hazards facilities and conducting interviews with safety expertsworking at mult
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Ever-increasing global water shortages necessitate more advanced and cost-effective water purification methods. Herein, a novel slow filtration system using natural raw zeolite is proposed as an alternative to traditional quartz sand as a filter medium. The system demonstrates excellent performance in reducing turbidity and removing methylene blue (MB). The natural zeolite-based filtration system
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Theories of predictive processing postulate that the brain continuously generates predictions about future linguistic input. Many different linguistic elements have been found to function as predictive cues. One such element is classifiers, i.e., morphemes that classify noun referents according to some semantic property. However, very few studies have so far investigated the predictive function of
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Popular Abstract in Swedish Ehrlichia hos människor och djur Fästingburna infektioner uppmärksammas alltmer både hos människor och djur. Fästingar har visat sig kunna överföra flera olika infektiösa agens som till exempel borrelia- och ehrlichiabakterier, tick-borne encephalitis (TBE)-virus och babesia-parasiter. De i Skandinavien förekommande ehrlichia-bakterierna Ehrlichia phagocytophila, orsakEhrlichia phagocytophila is a tick-borne pathogen of domestic animals, which has recently been acknowledged also as a human pathogen. It is a strictly intracellular bacterium, infecting granulocytes of the host, sometimes resulting in clinical disease - granulocytic ehrlichiosis - with manifestations ranging from mild flu-like conditions to severe infections with multi-organ failure and death. Thi
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Animal models greatly facilitate understanding of transmission, pathogenesis and immune responses in HIV and SIV infection and provide models for studies on the effect of candidate drugs or vaccines. However, there are several aspects that one should consider when drawing conclusions from results obtained from animal models. First, the genetic relationship of primate lentiviruses cannot be disrega
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Calculated absorbed dose distributions from tangential irradiation of the breast have been compared with TLD measurements in a anthropomorfic body-shaped phantom which has gone through all phases of the radiation treatment planning cycle, including mapping of electron densities with a CT scanner, simulation of beam set-up and several treatments with an accelerator. The absorbed doses, measured in
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β-Alanine synthase is the final enzyme of the reductive pyrimidine catabolic pathway, which is responsible for the breakdown of uracil and thymine in higher organisms. The fold of the homodimeric enzyme from the yeast Saccharomyces kluyveri identifies it as a member of the AcyI/M20 family of metallopeptidases. Its subunit consists of a catalytic domain harboring a di-zinc center and a smaller dime
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Epidemiological studies have indicated that chronic obstructive pulmonary disease (COPD) may be associated with an increased incidence of ischaemic cardiac events. The current authors performed a post hoc analysis of the European Respiratory Society's study on Chronic Obstructive Pulmonary Disease (EUROSCOP); a 3-yr, placebo-controlled study of an inhaled corticosteroid budesonide 800 pg-day-1 in
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The Chiffchaff Phylloscopus collybita is represented in Sweden by two different subspecies; the northern well-established abietinus and the southern recently established collybita which has expanded its range northward during the past two decades. At present, an area approximately 500 km wide separates the two subspecies. In order to document differences between the northern and southern populatio
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Improved expression of recombinant laccase by Pichia pastoris carrying the lcc1 cDNA isolated from Trametes versicolor was achieved by optimization of the cultivation conditions in a fermentor equipped with a methanol sensor system. The results indicated that the activity obtained in fermentor cultivations was at least 7 times higher than in shake-flask cultures. Three different strategies for fer
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Cornelia de Lange syndrome (CdLS; OMIM 122470) is a rare multiple congenital anomaly/mental retardation syndrome characterized by distinctive dysmorphic facial features, severe growth and developmental delay and abnormalities of the upper limbs. About 50% of CdLS patients have been found to have heterozygous mutations in the NIPBL gene and a few cases were recently found to be caused by mutations
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The aetiology of benign prostatic hyperplasia (BPH) remains unclear. The objective of the present study was to test the insulin, oestradiol and metabolic syndrome hypotheses as promoters of BPH. The design was a risk factor analysis of BPH in which the total prostate gland volume was related to endocrine and anthropometric factors. The participants studied were 184 representative men, aged 72-76 y
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The adsorption of water and coadsorption with oxygen on Rh{111} under ultrahigh vacuum conditions was studied using synchrotron-based photoemission and photoabsorption spectroscopy. Water adsorbs intact on the clean surface at temperatures below 154 K. Irradiation with x-rays, however, induces fast dissociation and the formation of a mixed OH+H2O layer indicating that the partially dissociated lay
