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Background: Acute pancreatitis (AP) is a common and potentially severe disease. Early identification of severity grade is crucial for the outcome of the patient. For study approaches and comparison of inter-institutional data the AP patients need to be uniformly classified.The aims of this thesis were to investigate the early stratifiation capacity of biomarkers in AP and to assess the morphologic
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The neurochemical profile of the cortex develops in a region and time specific manner, which can be distorted by psychiatric and other neurological pathologies. Pre-clinical studies often involve experimental mouse models. In this study, we determined the neurochemical profile of C57BL/6 mice in a longitudinal study design to provide a reference frame for the normal developing mouse cortex. Using
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Background: The Swedish Program for health surveillance of preschool children includes screening of language and communication abilities. One important language screening is carried out at age 4 years as part of a general screening conducted by health nurses at child health centres. The instruments presently in use for this screening mainly focus on expressive phonology. This may result in both ov
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We present the monolithic integration and electrical characterization of InAs nanowires (NWs) with the well-defined geometries and positions on Si as a platform for quantum transport studies. Hereby, one-dimensional (1D) ballistic transport with step-like 1D conductance quantization in units of 2e2/h is demonstrated for NWs with the widths between 28 nm and 58 nm and a height of 40 nm. The electri
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The aim of this study was to investigate calcium chloride-induced gelatinization of oat starch, and its effects on the properties of oat starch-based Pickering emulsions. The starch granules were gelatinized in CaCl2 for up to 24 h and the results indicate that the salt-induced gelatinization of oat granules is not a surface phenomenon, as gelatinization and dissolution of the whole starch granule
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This population-based time-trend study examines gun violence rates among males in Sweden during the years 1996 to 2015 and compares the rate in Sweden to other Western European countries. Data were collected from six registries and are presented descriptively per 100,000 inhabitants. The risks among males in Sweden increased considerably in both lethal and non-lethal gun victimization and perpetra
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This paper presents an updated checklist of the butterflies of Europe, together with their original name combinations, and their occurrence status in each European country. According to this checklist, 496 species of the superfamily Papilionoidea occur in Europe. Changes in comparison with the last version (2.6.2) of Fauna Europaea are discussed. Compared to that version, 16 species are new additi
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Familial risks for cancer are important for clinical counseling and understanding cancer etiology. The nationwide Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0 to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Urological cancer cases were retrieved from the Swedish Cancer Registry up to year 2000. Standardized incidence ratios (SIR
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Effects of short-term infusion and long-term injection of gastric inhibitory polypeptide (GIP) on changes in pancreatic lipase and colipase contents in rats were studied, and mRNAs encoding for lipase and colipase were determined by Northern blot hybridization with specific cDNA probes. GIP infused at a dose of 3 micrograms/h for 24 h significantly increased the pancreatic lipase content by 34% (P
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I sex fallstudier vid fyra medelstora verkstadsföretag inom mekanisk industri utvecklades en metodik för att analysera och beskriva existerande och planerad arbetsmiljö och produktion med hjälp av datorgenererade bilder. Användningen av bilder skedde inom ramen för en aktionsforskningsmetodik, där chefer och berörda anställda tillsammans med fack och representanter för företagshälsovården samverka
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Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumference and waist-hip ratio from up to 200,452 adults of European (n = 180,423) or other ancestry (n = 20,029). We standardized PA by categorizing it int
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Editorial: This focus is dedicated to a special trend on the scenes of contemporary music: composers going on stage to perform their own pieces.The presented articles were developed during my research project 'The Creator on Stage'. They can be read as selection of perspectives, commentaries, analyses, reflections and gained knowledge-production on the topic.The intention with the project was part
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The description of ultrafast nonadiabatic chemical dynamics during molecular photo-transformations remains challenging because electronic and nuclear configurations impact each other and cannot be treated independently. Here we gain experimental insights, beyond the Born-Oppenheimer approximation, into the light-induced spin-state trapping dynamics of the prototypical [Fe(bpy) 3 ] 2+ compound by t
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The presence of activated protein C resistance, plasma hyperhomocysteinemia and the MTHFR C677T mutation in patients with central retinal vein occlusion were investigated and compared to a control group. Activated protein C resistance was overrepresented in the group of patients less than 50 years of age whereas this was not the case in patients more than 50 years of age. Neither hyperhomocysteine
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Popular Abstract in Swedish Reumatoid artrit/ledgångsreumatism (RA) är en kronisk inflammatorisk sjukdom som i första hand drabbar lederna. Man uppskattar sjukdomens förekomst i den vuxna befolkningen till cirka en halv procent och den är 2-4 gånger vanligare hos kvinnor. Vi vet inte vad som orsakar RA, men såväl ärftliga som omgivningsfaktorer har betydelse. RA har ett varierande förlopp. Dels kaRheumatoid arthritis (RA) is characterized by persistent inflammation, progressive joint damage and disability. This thesis describes the outcome after 10 years in a cohort of 183 RA patients (116 women, 67 men) recruited 1985-89. The mean age was 51 years and symptom duration 11 months at inclusion. Standardized clinical, biochemical and radiographic assessments were performed annually. Health st
