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The underlying reasons for gender differences in smoking behavior, and thus for the recent trends, are not well understood. Using a sample of 8592 Swedish adolescents aged 15-18, this paper contributes to the literature by exploring gender differences in smoking risk perceptions and in the responses to the latter. The results show significant gender differences in the perception of smoking mortali
Inorganic nutrient availability and temperature are recognized as major regulators of organic carbon processing by aquatic bacteria, but little is known about how these two factors interact to control bacterial metabolic processes. We manipulated the temperature of boreal humic stream water samples within 0-25 degrees C and measured bacterial production (BP) and respiration (BR) with and without i
Background: In previous meta-analyses, tea consumption has been associated with lower incidence of type 2 diabetes. It is unclear, however, if tea is associated inversely over the entire range of intake. Therefore, we investigated the association between tea consumption and incidence of type 2 diabetes in a European population. Methodology/Principal Findings: The EPIC-InterAct case-cohort study wa
Background: Animal studies suggest that the arginine vasopressin (AVP) system plays a role in glucose and fat metabolism, but data from humans are limited. Method and results: We analysed plasma copeptin (copeptin), a stable C-terminal fragment of the AVP pro-hormone in the large, Swedish, population-based cohort Malmö Diet and Cancer Study Cardiovascular Cohort (MDC-CC, n=6103). Using baseline
The present study investigates the nature of the link between the staphylococcal enterotoxin A (SEA) gene and the lifecycle of Siphoviridae bacteriophages, including the origin of strain variation regarding SEA production after prophage induction. Five strains representing three different genetic lines of the sea region were studied under optimal and prophage-induced growth conditions and the Siph
This investigation makes a survey of the spread of fire and the fire development in low-rise residential building areas through obtaining the literal knowledge of factors having influence on a fire in one burning building and fire spread between buildings within a group of single-family houses. The purpose of the investigation was, on basis of the knowledge, to propose improved measures and the ch
Studies of determinants of development of inhibitory antibodies to factor VIII in people with hemophilia A indicate a complex process involving multiple factors. The Hemophilia Inhibitor Genetics Study Combined Cohort was formed to extend understanding of the genetic background of risk. The study group contains 833 subjects from three independent cohorts: brother pairs and singletons with and with
Ultra-fast substitution of chloride for bromide, iodide, azide and thiocyanate trans to ethene in Zeise's anion, [PtCl3(C2H4)](-), 1, has been investigated in methanol solvent by use of cryo temperature diode array stopped-flow spectrophotometry. Reactions follow the usual two-term rate law for square-planar substitutions, k(obs)=k(1)+k(2)[Y] (where k(1)=k(MeOH) [MeOH]), with k(1)=118+/-10 s(-1) a
Yeast-derived zymosan beads are among the classical agents used to induce sterile inflammatory responses in experimental animals and macrophage activation in cell culture. In macrophages the cytosolic phospholipase A2 becomes activated, leading to mobilization of arachidonate and the generation of prostaglandins and leukotrienes. Although zymosan can interact with several receptors it has not been
Immunoassays for haptens depend on competitive hapten-anti-hapten reactions, and consequently their sensitivities are significantly influenced by the affinities of anti-hapten antibodies. Thus, genetically engineered antibodies, which have much higher affinities than native antibodies, should increase assay sensitivities. Here, we created a mutated single-chain Fv fragment (scFv) against estradiol
Pigs from 154 litters (n = 1132, 19 +/- 3 days of age, 4.9 +/- 1.1 kg of bodyweight) were used in a 3 x 2 factorial design to evaluate two raw materials with nutraceutical properties being used in feeds, spray-dried porcine plasma (SDPP) and a yeast protein meal, and their effects on growth performance, immune parameters and gastrointestinal adaption of piglets to weaning. Factors included dietary
Background We investigated whether prediagnostic reported intake of dairy products and dietary calcium are associated with colorectal cancer (CRC) survival. Methods Data from 3,859 subjects with CRC (42.1% male, mean age at diagnosis 64.2 ± 8.1 years) in the European Investigation into Cancer and Nutrition (EPIC) cohort were analyzed. Intake of dairy products and dietary calcium was assessed at ba
The composition of the colonic microflora is essential for the health of the human host. To be able to survive, the microflora is dependent of a continuous supply of substrate. In this respect dietary fibre and other indigestible carbohydrates, of which the consumption in affluent societies is generally low, are of great importance. Numerous of studies have demonstrated beneficial effects of dieta
Surface display in insect cells: Systems available for surface display that utilize bacterial phages are insufficient for displaying a number of eukaryotic proteins. By instead presenting proteins on the surface of eukaryotic cells or virus, some of these problems might be overcome. The baculovirus/insect cell system, which has a high expression rate and post-translational mashinery closely resemb
BACKGROUND: Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in Blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an acute compensatory mechanism when there is a disruption in volume-loading homeostasis, i.e. when cardiac stress is evident. Whether DefS will influence associations between copepti
CONTEXT: Carpal tunnel syndrome (CTS) is a cause of pain, numbness, and tingling in the hands and is an important cause of work disability. Although high prevalence rates of CTS in certain occupations have been reported, little is known about its prevalence in the general population. OBJECTIVE: To estimate the prevalence of CTS in a general population. DESIGN: General health mail survey sent in Fe
Traditionally, most funding is made available when a disaster occurs. Disaster re-sponse is the implementation of what humanitarian actors did (or didn't do) in pre-paredness for any intervention. Based on a case study of a logistics change in the International Federation of Red Cross Red Crescent Society, this paper discusses how more funding of preparedness can radically improve the speed and qu
Background: Vascular-targeted photodynamic therapy, a novel tissue-preserving treatment for low-risk prostate cancer, has shown favourable safety and efficacy results in single-arm phase 1 and 2 studies. We compared this treatment with the standard of care, active surveillance, in men with low-risk prostate cancer in a phase 3 trial. Methods: This randomised controlled trial was done in 47 Europea
BACKGROUND/AIM: Cervical cancer is associated with poorer diagnosis among the elderly and pap-smear screening has a lower sensitivity. Self-sampling for detection of high-risk human papillomavirus (hr-HPV) may be an alternative screening method. The aim of this study was to analyze the response rate to vaginal HPV self-sampling and the HPV mRNA prevalence among women 69-70 years. MATERIALS AND MET
