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The present day global climate change is fueled by our use of fossil fuels and land use change. The already observed warming and other distinct changes in the climate system stem from these human influences and are ongoing. Due to climate system inertia, a part of the climate system's response to this historical forcing remains to manifest itself, which it will do over time. At the same time, soci
Despite a variety of testing approaches, it is often difficult to make an accurate diagnosis of Alzheimer's disease (AD), especially at an early stage of the disease. Diagnosis is based on clinical criteria as well as exclusion of other causes of dementia but a definitive diagnosis can only be made at autopsy. We have investigated the diagnostic value of a 96-gene expression array for detection of
Genomic aberrations of key regulators of the apoptotic pathway have hardly been identified in neuroblastoma. We detected high BCL2 mRNA and protein levels in the majority of neuroblastoma tumours by Affymetrix expression profiling and Tissue Micro Array analysis. This BCL2 mRNA expression is strongly elevated compared to normal tissues and other malignancies. Most neuroblastoma cell lines lack thi
Physiological studies on olfaction frequently ignore the airborne quantities of stimuli reaching the sensory organ. We used a gas chromatography-calibrated photoionization detector to estimate quantities released from standard Pasteur pipette stimulus cartridges during repeated puffing of 27 compounds and verified how lack of quantification could obscure olfactory sensory neuron (OSN) affinities.
Abstract in UndeterminedThe question of how new regional growth paths emerge has been raised by many leading economic geographers. From an evolutionary perspective, there are strong reasons to believe that regions are most likely to branch into industries that are technologically related to the preexisting industries in the regions. Using a new indicator of technological relatedness between manufa
Weak alignment of requirements engineering (RE) with verification and validation (VV) may lead to problems in delivering the required products in time with the right quality. For example, weak communication of requirements changes to testers may result in lack of verification of new requirements and incorrect verification of old invalid requirements, leading to software quality problems, wasted ef
The spruce coneworm, Dioryctria abietella Denis & Schiffermüller (Lepidoptera: Pyralidae), is a major pest in spruce seed orchards in Europe. Initial work on its pheromone ecology reported significant attraction of males to (9Z,11E)-tetradecadienyl acetate (9Z,11E-14:OAc), but this compound appeared to be a very weak attractant in field trials. In this study, we show that a second female-produ
Recent research does not show an association between fruit and vegetable consumption and bladder cancer risk. None of these studies investigated variety in fruit and vegetable consumption, which may capture different aspects of consumption. We investigated whether a varied consumption of vegetables and fruits is associated with bladder cancer risk in the European Prospective Investigation into Can
In this communication, we analyse the passage of oxygen and carbon dioxide over the respiratory membrane. The lung surfactant membrane at the alveolar interface can have a very special arrangement, which affects the diffusional transport. We present a theoretical model for the diffusion of small molecules in membranes with a complex structure, and we specifically compare a membrane composed of a t
Enriched environment (EE) housing significantly ameliorates neurological deficits induced by cortical brain ischemia without changing infarction size, suggesting that EE-related functional benefits are associated with neuronal plasticity events in the remaining tissue. Brain-derived neurotrophic factor (BDNF), nerve growth factor-induced gene A (NGFI-A) and corticosteroid receptors (mineralocortic
The MBA case method of how to use cases steam from Harvard and has almost become a norm for what the case method represents concerning the purpose, form and content. However, the Lund University School of Economics and Management (LUSEM) way of using cases differs from the MBA Case Method in several important aspects. This paper discusses the potential merits of using an alternative approach (LUSE
Popular Abstract in Swedish I denna studie beskrivs och analyseras högskolelärares personliga teorier om sin pedagogiska praktik i högskolans grundutbildning. I anslutning till t.ex. Polanyi (1958) och Bourdieu (1990) har högskolelärare utvecklat en personlig praktisk teori som deltagare i ett akademiskt socialt sammanhang, först som studenter sedan som lärare. Denna kan ses som deras ”pedagogik” In this study university teachers? personal theories of their pedagogical practice in basic courses in undergraduate education are described and analyzed. According to for example Polanyi (1958) and Bourdieu (1990) university teachers have developed a personal practical theory as participators in an academic social context, first as students then as teachers. This can be seen as their ?pedagogy? a
Aim: The Driving to Learn project focused on people with profound cognitive disabilities and their possible achievements from practicing joystick-use in a powered wheelchair. The aim of this study within the project was to statistically analyse the participants' outcomes, and to explore factors, in terms of participant and training characteristics, associated with a favourable outcome of training
Gas turbines emissions, NOX in particular, have negative impact on the environment. To limit the emissions gas turbine burners are constantly improved. In this work, a fourth generation SIT (Siemens Industrial Turbomachinery) burner is studied to gain information about the formation of NOX emissions. The gas mixtures for the full burner are limited to natural gas with different nitrogen dilutions.
Introduction: Epidemiological studies suggest atherosclerosis as a common risk factor between cardiovascular diseases and erectile dysfunction (ED). We aimed to determine the association between erectile function and the biomarkers of subclinical atherosclerosis in 119 middle-aged healthy men from the general population. Methods: Erectile function was assessed using the International Index of Erec
Mitochondrial disorders cause energy failure and metabolic derangements. Metabolome profiling in patients and animal models may identify affected metabolic pathways and reveal new biomarkers of disease progression. Using liver metabolomics we have shown a starvation-like condition in a knock-in (Bcs1lc.232A>G) mouse model of GRACILE syndrome, a neonatal lethal respiratory chain complex III dysfunc
Axons show a poor regenerative capacity following traumatic central nervous system (CNS) injury, partly due to the expression of inhibitors of axonal outgrowth, of which Nogo-A is considered the most important. We evaluated the acute expression of Nogo-A, the Nogo-66 receptor (NgR) and the novel small proline-rich repeat protein 1A (SPRR1A, previously undetected in brain), following experimental l
Semiconductor nanowire arrays have been identified as a promising platform for future light emitting diodes (LEDs), for example, due to the materials science freedom of combining lattice-mismatched materials in them. Furthermore, the emission of light from nanowires can be tailored by designing their geometry. Such tailoring could optimize the emission of light to the top side as well as enhance t
Partially premixed combustion (PPC) is used to meet the increasing demands of emission legislation and to improve fuel efficiency. With gasoline fuels, PPC has the advantage of a longer premixed duration of the fuel/air mixture, which prevents soot formation. In addition, the overall combustion stability can be increased with a longer ignition delay, providing proper fuel injection strategies. In
