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Popular Science Summary Konsten att kunna ta bort ett syre Alla celler har DNA, som måste repareras och kopieras för att livet ska fortgå. För att kunna göra detta måste det finnas byggstenar. En av alla processer som ser till att alla delar finns i rätt mängd innefattar bara ett protein. Ett protein som får instruktioner från många håll för att gå igenom en komplicerad process som tillverkar dessThe protein ribonucleotide reductase catalyses the de novo synthesis of deoxyribonucleotides (dNTPs) from ribonucleotides (NTPs), using radical chemistry. It is under strict allosteric regulation, partly from the dNTPs it synthesises that regulate what substrate should be synthesised, but also from dATP/ATP, which regulates overall activity. It is a protein that is found in almost every living org

Title: “Language is access to everything” - A qualitative study of SFI-teachers' experience of the transition to digitalized distance education. Authors: Rania Elwan and Fitore Mehmeti Supervisor: Karin Kullberg Assessor: Maria Bergendal Arvidsson The purpose of the study is to investigate from teachers for Swedish for immigrants (SFI) perspective how the transition to digitalized distance ed

Data from field experiments carried out in the swash zone on two Pacific beaches in Japan were analyzed to determine net sediment transport rates and the resulting foreshore response. The experiments involved artificial modification of the foreshore slope with a bulldozer, either making the slope steeper or milder, after which a wide range of measurements were performed as the slope evolved back t

Although long-acting inhaled beta(2)-agonists improve various outcome measures in COPD, no double-blind study has yet shown a significant effect of these drugs on exercise capacity. In a randomized, double-blind, placebo-controlled, crossover study, patients received formoterol (4.5,9, or 18 mug b.i.d via Turbuhaler(R)), ipratroplum bromide (80 mug t.i.d via pMDI with spacer), or placebo for I wee

A sensitive biosensor has been developed for the neurotoxin beta-N-oxalyl-alpha,beta-diaminopropionic acid (beta-ODAP) contained in the seeds of grass pea (Lathyrus sativus) and for L-glutamate based on glutamate oxidase (GlOx) and a Prussian blue (PB) modified glassy carbon (GC) electrode. The configuration of the system is so as to detect the hydrogen peroxide released during the enzymatic cycle

In previous studies, glucagon receptor knockout mice (Gcgr(-/-)) display reduced blood glucose and increased glucose tolerance, with hyperglucagonemia and increased levels of glucagon-like peptide (GLP)-1. However, the role of glucagon receptor signaling for the regulation of islet function and insulin sensitivity is unknown. We therefore explored P-cell function and insulin sensitivity in Gcgr(-/

Flygprestanda AB make software and databases for hundreds of airline companies all over the world. Their services include both software development and technical-engineering calculations with focus on delivering all information needed to perform a commercial flight from one place to another. The company is currently developing a web system with Google Web Toolkit which will be used within the comp

The current financial crisis the US and the world finds itself embroiled in has all of the markings of a once-in-a-generation type of economic contraction. In times like these, it is natural to search for comparable frames of reference; Japan’s own banking crisis during the “lost decade” of the 1990’s provides significant parallels to the current state of affairs. Given the severity and relative r

To allow the user interface in a mobile phone more space, slide modules are implemented. The usage of slide modules introduces many new challenges when designing a mobile phone. New solutions to these challenges is the main scope for this thesis. Nokia currently has several different slide phones out on the market implementing some sort of slide module. The slide module provides extra space for th

Rådets direktiv 2001/23/EG om tillnärmning av medlemstaternas lagstiftning om skydd för arbetstagares rättigheter vid överlåtelse av företag, verksamheter eller delar av verksamheter antogs ursprungligen år 1977 som en följd av ökade omstruktureringar och företagsöverlåtelser på den gemensamma marknaden. En viktig bestämmelse återfinns i artikel 3, som stadgar en automatisk övergång från överlåtarThe Council Directive 2001/23/EC on the approximation of the laws of the Member States relating to the safeguarding of employees’ rights in the event of transfers of undertakings, businesses or parts of businesses, was originally adopted in 1977 as a result of an increase in restructurings and transfers of businesses. An important provision is found in article 3, which prescribes the automatic tra

Food insecurity is a reality faced by millions of people worldwide. Poor access and availability to food markets, poverty, and uncertain global system futures all exacerbate this issue. In seeking to combat food insecurity for South Carolina residents and improve the viability and resilience of local food markets around Greenville County, South Carolina, this assessment determines optimal potentia

Popular Abstract in Swedish I denna studie beskrivs och analyseras högskolelärares personliga teorier om sin pedagogiska praktik i högskolans grundutbildning. I anslutning till t.ex. Polanyi (1958) och Bourdieu (1990) har högskolelärare utvecklat en personlig praktisk teori som deltagare i ett akademiskt socialt sammanhang, först som studenter sedan som lärare. Denna kan ses som deras ”pedagogik” In this study university teachers? personal theories of their pedagogical practice in basic courses in undergraduate education are described and analyzed. According to for example Polanyi (1958) and Bourdieu (1990) university teachers have developed a personal practical theory as participators in an academic social context, first as students then as teachers. This can be seen as their ?pedagogy? a

Background: Cytokine response is an important factor in the development of shock and organ failure. The aim of this study was to investigate intraperitoneal (peritoneal) and venous (systemic) postoperative cytokine release after major surgery. Methods: Major abdominal surgery was performed in 19 patients. Preoperative systemic measurements and postoperative systemic and peritoneal measurements of

Objectives: The aim of this study was to investigate the influence of specific components of Andersen's behavioural model on adult individuals' perceived oral treatment need. Methods: A questionnaire was sent to a randomly selected sample of 9,690 individuals, 20 to 89 years old, living in Skane, Sweden. The 58 questions, some with follow-up questions, were answered by 6,123 individuals; a 63% res

Aims. The present study was conducted to determine the optical extinction curve for Cerro Paranal under typical clear-sky observing conditions, with the purpose of providing the community with a function to be used to correct the observed spectra, with an accuracy of 0.01 mag airmass(-1). Additionally, this work was meant to analyze the variability of the various components, to derive the main atm

Cholera toxin (CT) binds to GM1-ganglioside receptors present on all nucleated cells. Despite this, it is a very potent mucosal adjuvant that has a dramatic impact on immune cells, as well as nerve and epithelial cells, causing diarrhea. This fact has hampered our understanding of whether the adjuvanticity of CT is direct or indirect, as cells that bind CT may or may not be involved in its adjuvan

Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Methods Estimate

Volatiles from chocolate mediate upwind flight behavior in Ephestia cautella and Plodia interpunctella. We used gas chromatography with electroantennographic detection and found 12 active compounds derived from three different chocolate types, i.e., plain, nut-containing, and rum-flavored. Eight of the compounds were identified with mass spectrometry, and the activity of three compounds, ethyl van

In a 24-year sub-sample taken from a 42-year period of study (1950-1991), hip fracture incidence was analysed from a defined catchment area within one hospital. During this time, 8,256 hip fractures occurred in a generated risk population of 1,915,571 person-years. Crude incidence increased three-fold in women and five-fold in men. In men, the age-specific increase was twice as large as the age dr