Filtyp
Increased levels of intact parathyroid hormone (PTH) have been documented after surgery for primary hyperparathyroidism (pHPT) despite normocalcemia. The pathogenesis remains to be elucidated. Seventeen consecutive patients operated on for solitary parathyroid adenoma were investigated before and at 8 weeks and 1 year after surgery with serum levels of intact PTH, biochemical variables known to re
BACKGROUND: Vascular endothelial dysfunction, accelerated thickening of arterial intima, and changes in ventricular repolarization contribute to increased cardiovascular morbidity in type 1 diabetes (T1D). Although vitamin C has important antioxidant functions and increased oxidative stress is a central mechanism of cardiovascular dysfunction in T1D, the relation between vitamin C and the cardiova
Object Cerebral ischemia remains the key cause of disability and death in the late phase after subarachnoid hemorrhage (SAH), and its pathogenesis is still poorly understood. The purpose of this study was to examine whether the change in intracranial pressure or the extravasated blood causes the late cerebral ischemia and the upregulation of receptors or the cerebral vasoconstriction observed foll
Objective: Our aim was to compare the ability of radiologists to detect breast cancers using one-view breast tomosynthesis (BT) and two-view digital mammography (DM) in an enriched population of abnormal (diseased) patients and benign and/or normal (healthy) patients. Methods: All participants gave informed consent. The BT and DM examinations were performed with about the same average glandular
Gonadotropin-releasing hormone (GnRH) analogs are given to women undergoing in vitro fertilization. Case reports describing the development of chronic intestinal pseudo-obstruction and auto-antibodies against GnRH after such treatment suggest a strong association between intestinal dysfunction and GnRH analogs. No experimental model for studying such a relationship is currently at hand. Our main g
We have previously shown that persistent a-synuclein overexpression in ventral midbrain of marmoset leads to a distinctive neurodegenerative process and motor defects. The neurodegeneration was confined to caudate putamen dopaminergic fibers in animals overexpressing wild-type (wt) alpha-synuclein. However, A53T alpha-synuclein overexpression induced neurodegeneration that resulted in nigral dopam
This master project has been carried out in collaboration with a research project named “Valuation of cultural ecosystem services based on contributions to quality of life” at Lund University. In this thesis, Cultural Ecosystem Services (CES) are evaluated from people’s own perceptions. The very aim of the study is to develop a method to assess CES non-monetarily by using a bottom-up perspective.
Bakgrund: Obesitas och psykisk ohälsa tillhör de största globala hälsoutmaningarna i modern tid och har under de senaste decennierna varit ett växande problem. Människor har fått en mer stillasittande livsstil och större tillgång på kaloririk föda. Faktorerna som påverkar prevalensen är många men att det behöver ske en förändring är säkert. Syfte och frågeställningar: Syftet var att kartlägga BMI,
The possibility to have a strongly first order electroweak phase transition, which is one of the Sakharov conditions for electroweak baryogenesis together with $\mathcal{CP}$ violation and baryon number violation, in general Two-Higgs-Doublet Models (2HDMs) is here investigated. Different kinds of $\mathbb{Z}_{2}$ breaking beyond standard assumptions are studied, in particular by allowing it to be
Forest ecosystems provide a wide range of services necessary for maintaining environmental health and human well-being. Ecosystem models help inform how various management strategies respond in different regions to changing climate conditions. They contribute to mitigation and adaptation policy measures and support private forest owners in deciding ideal practices to implement. The complex nature
In order to analyse the human postural control system single-stimulus multi-response measurement experiments are made, where the body sway due to an induced disturbance on the calf muscles are recorded with force platforms, Selspot systems or EMG-equipments. The measured outputs are usually analysed one by one as for a Single-Input Single-Output system. In this study a Single-Input Multi-Output ap
Våren 2024 röstades ett omdebatterat lagförslag igenom i den svenska riksdagen. Under juli 2025 ersätts lag (1972:119) om fastställande av könstillhörighet i vissa fall – könstillhörighetslagen – med en ny. Den nya lagen reducerar rådande 18-årsgräns för det juridiska könsbytet; 16-åringar ska ges möjlighet att ta beslut i frågan, med vårdnadshavares medgivande. Under det senaste decenniet har fIn the spring of 2024, a contentious legislative proposal was voted through in the Swedish parliament. In July 2025 the gender recognition act will be replaced. The new law will reduce the age limit for the right to change legal gender from 18 to 16 years of age, with the consent of the guardians of the youth concerned. Over the last decade, several initiatives have been raised with the objective
This study aims to investigate the impact of natural disasters on stock market returns and volatility in the European insurance sector using daily financial data from 3 January 2000 to 2 January 2025. This is done by implementing a GARCH(1,1) model to both the STOXX Europe 600 Insurance index and the broader Euro STOXX 600 index, as well as firm-level data for five of the largest European insurers
Precision cut tumor slices (PCTS) are used as an ex vivo tissue model to study the tumor microenvironment (TME), immune interactions and treatment-induced effects.They allow researchers to analyze individual patient responses to therapies, making them valuable for personalized medicine. In this study, PCTS generated from five biopsy samples collected from patients with head and neck cancer or esop
The rise of the internet, social media, and populist leaders in recent years has turned attention towards conspiracy theories, making them appear as phenomena which are becoming increasingly widespread. Although conspiracy beliefs have not necessarily increased over time, their growing visibility has emphasized the negative consequences associated with belief in them, such as heightened political
This study investigated the effect of polar lipids from different sources on the in vitro starch digestion rate of bread. Postprandial glycaemic response is strongly influenced by the rate of starch digestion, and polar lipids have been suggested to modulate this process, although the underlying mechanisms remain unclear. Bread was used as a model food matrix, and five types of bread were prepared
Background: Inhaled nanomaterials can translocate from the lungs into systemic circulation and reach the liver, which is the main secondary organ for nanomaterial uptake, potentially causing adverse effects. Understanding how inhaled nanomaterials localize within liver tissue is important for understanding their clearance mechanisms and potential toxicity. Previous in vivo studies have primarily f
Introduction How the burden of disease varies during different phases after floods and after storms is essential in order to guide a medical response, but it has not been well-described. The objective of this review was to elucidate the health problems following flood and storm disasters.Methods: A literature search of the databases Medline (US National Library of Medicine, National Institutes of
1. Primary Raynaud's phenomenon (PRP) is characterized by increased vasoconstrictor tone that develops during exposure to cold. The symptoms are most pronounced during the winter months with low outdoor temperature. The L-arginine-nitric oxide (NO)-cyclic GMP (cGMP) pathway plays an important role in counteracting vasospasm. The aim of the present study was to investigate if the venous cGMP respon
Changes in environmental temperature during development can affect growth, metabolism and temperature tolerance of the offspring. We know little about whether such changes remain to adulthood, which is important to understand the links between climate change, development and fitness. We investigated whether phenotypic consequences of the thermal environment in early life remained in adulthood in t
