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BACKGROUND: Negative-pressure wound therapy is believed to accelerate wound healing by altered wound edge microvascular blood flow. The current standard negative pressure is -125 mmHg. However, this pressure may cause pain and ischemia and often has to be reduced. The aim of the present study was to examine the blood flow effects of different levels of negative pressures (-10 to -175 mmHg). METHOD

Objective. While the prevalence of radiographic thumb carpometacarpal (CMC1) osteoarthritis (OA) is well-described, little is known about clinically symptomatic disease presenting to physicians for care. We sought to determine the prevalence of doctor-diagnosed CMC1 OA. Methods. Using health care data from Skane in southern Sweden (population 1.24 million), we identified all adults ages >= 20 year

Background: Cyclosporine (CsA) or infliximab (IFX) are used as rescue therapies in steroid-refractory, severe attacks of ulcerative colitis (UC). There are no data comparing the efficacy of these two alternatives. Methods: Outcome of rescue therapy was retrospectively studied in two cohorts of patients hospitalized due to steroid-refractory moderate to severe UC: 1) a Swedish-Danish cohort (n 49)

BACKGROUND: We previously reported that a single prostate-specific antigen (PSA) measured at ages 44-50 was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. Here we report an additional 7 years of follow-up. This provides replication using an independent data set and allows estimates of the association between early PSA and subsequent advanced cancer (clinical

We use formaldehyde (HCHO) vertical column measurements from the Scanning Imaging Absorption spectrometer for Atmospheric Chartography (SCIAMACHY) and Ozone Monitoring Instrument (OMI), and a nested-grid version of the GEOS-Chem chemistry transport model, to infer an ensemble of top-down isoprene emission estimates from tropical South America during 2006, using different model configurations and a

BACKGROUND: It is controversial whether breast reconstruction with a microvascular free flap should be done without restrictions in patients who have not had radiotherapy. Many regard it as too expensive, but some consider it better and more economically advantageous than an implant reconstruction. METHODS: Databases of publications were searched to find out under what conditions is it suitable to

Objectives: To assess correlations between Kellgren & Lawrence (KL) gradings, minimum joint space width (mJSW) measurements and the Boston Leeds Osteoarthritis Knee Score (BLOKS) within a cohort of obese patients with knee osteoarthritis (KOA). Methods: 192 Participants were recruited from an outpatient clinic (ClinicalTrials.gov: NCT00655941). Inclusion criteria were age >= 50 years, body mas

ObjectiveThe focus of this study was on the impact of spousal loss on the development of chronic pain thereafter. More specifically, the aim was to investigate the effect of experiencing low preparedness before a wife's death and the widower's chronic pain 4-5 years after loss. MethodsIn a population-based study in the years 2004-2005, anonymous questionnaires were sent out to 907 men in Sweden wh

Subject Objective: To assess the accuracy of a portable monitoring device based on peripheral arterial tonometry to diagnose obstructive sleep apnea (OSA). To propose a new standard for limited-channel device validation using synchronized polysomnography (PSG) home recordings and a population-based cohort. Design: Single-night, unattended PSG and Watch_PAT 100 (WP_100). Setting: Home environment.

An air sampling method for the determination of isocyanates. aminoisocyanates and amines formed during the thermal degradation Of polyurethane (PUR) is presented. The method is based on the collection of air samples using impinger flasks containing di-n-butylamine (DBA) in toluene with a glass fibre filter in series. Isocyanates are derivatized with DBA to urea derivatives, and amines are derivati

A numerical study of how changes in the micromechanical modeling affect the formability of voided metal sheets is conducted. A homogenization technique, where periodic representative volume elements are used, permits investigations of the global formability where the local material mechanisms and the microstructure are accounted for. A nonlocal material model, containing a constitutive material le

One problem with web servers is that they are sensitive to overload. The servers may become overloaded during temporary traffic peaks when more requests arrive than the server is designed for. Because overload usually occurs rather seldom, it is not economical to overprovision the servers for these traffic peaks, instead admission control mechanisms can be implemented in the servers. This pa per i

The effect of hydrogen enrichment to natural gas flames was experimentally investigated at atmospheric pressure conditions using flame chemiluminescence imaging, planar laser-induced fluorescence of hydroxyl radicals (OH PLIF) and dynamic pressure monitoring. The experiments were performed using a 3rd generation dry low emission (DLE) burner used in both SGT-700 and SGT-800 industrial gas turbines

To improve gas turbine performance, the operating temperature has been increased continuously. However, the heat transferred to the turbine blade is substantially increased as the turbine inlet temperature is increased. Cooling methods are therefore needed for the turbine blades to ensure a long durability and safe operation. The blade tip region is exposed to the hot gas flow and is difficult to