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MRI and non-cartilaginous structures in knee osteoarthritis

Magnetic resonance imaging (MRI) provides a sensitive tool for examining all the structures involved in the osteoarthritis (OA) process. While much of the MRI literature previously focussed on cartilage, there is increasing research on whole-organ evaluation and including features such as synovitis, bone marrow edema, and meniscal and ligamentous pathology. The aim of this session at the Outcome M

Three-dimensional analysis of compaction of metal powder

Three-dimensional compaction simulations of geometries with circular and quadratic cross-sections are reported using dilatant viscoplastic material models representing a ductile steel powder. The simulations are compared with experiments using in situ measurements of the wall-tractions within the die. Two different porous viscoplastic material models have been used: the combined Fleck-Kuhn-MeMeeki

S100beta after coronary artery surgery: release pattern, source of contamination, and relation to neuropsychological outcome

BACKGROUND: S100beta has been suggested as a marker of brain damage after cardiac operation. The aim of this study was to characterize the early S100beta release in detail and relate it to neuropsychological outcome. METHODS: Three groups of patients were investigated. All patients underwent coronary artery bypass surgery (CABG) with extracorporeal circulation. In group A, 110 patients had samplin

End-of-life decision making in Europe and Australia - A physician survey

Background: The frequencies with which physicians make different medical end-of-life decisions (ELDs) may differ between countries, but comparison between countries has been difficult owing to the use of dissimilar research methods. Methods: A written questionnaire was sent to a random sample of physicians from 9 specialties in 6 European countries and Australia to investigate possible differences

HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine

The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day I and at 6-12 months intervals for up to 48 months, subjects underwent Papanicolaou and genital HPV testing. N

Diabetes – en sjukdom med många ansikten – Vetenskap och Hälsa

Diabetes – en sjukdom med många ansikten – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Diabetes – en sjukdom med många ansikten 2010-05-18 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Stress minskar både produktion och verkan av insu

https://www.vetenskaphalsa.se/diabetes-en-sjukdom-med-manga-ansikten/ - 2026-06-19

Fallgropar som för forskningen framåt – Vetenskap och Hälsa

Fallgropar som för forskningen framåt – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Fallgropar som för forskningen framåt 2014-03-31 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. En vanlig bild av forskningen är att forskare gör exper

https://www.vetenskaphalsa.se/fallgropar-som-for-forskningen-framat/ - 2026-06-19

Sund livsstil minskar risken för hjärtsjukdomar oberoende av genetisk risk – Vetenskap och Hälsa

Sund livsstil minskar risken för hjärtsjukdomar oberoende av genetisk risk – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Sund livsstil minskar risken för hjärtsjukdomar oberoende av genetisk risk 2016-11-15 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön

https://www.vetenskaphalsa.se/sund-livsstil-minskar-risken-for-hjartsjukdomar-oberoende-av-genetisk-risk/ - 2026-06-19

High-resolution Late Silurian correlations between Gotland, Sweden and the Broken River region, NE Australia: Lithologies, conodonts and isotopes

High-resolution correlations, partly with a precision better than 10 ka, are achieved between late Ludfordian sequences on Gotland, Sweden (on Baltica), and a section (COG) through the Coral Gardens Formation along the Broken River, northeastern Australia (on Gondwana), despite these sections having been on different palaeocontinents facing different oceans. The interval is characterised by rapid,

Shogenji's Measure of Justification and the Inverse Conjunction Fallacy

This paper takes issue with a recent proposal due to Shogenji (Synthese 184:29-48, 2012). In his paper, Shogenji introduces J, a normatively motivated formal measure of justification (and of confirmation), and then proceeds to recruit it descriptively in an explanation of the conjunction fallacy. We argue that this explanation is undermined by the fact that it cannot be extended in any natural way

A Geant4 Simulation Package for the TASISpec Experimental Detector Setup

The experimental detector setup TASISpec (TA SCA in Small Image mode Spectroscopy) comprises composite Ge- and highly segmented Si-detectors. The setup is constructed to provide multi-coincidence spectroscopic data between gamma-rays, X-rays, conversion electrons, fission fragments, and alpha-particles for heavy and superheavy elements (Z >= 100). The full array has been virtually constructed usin

Magnetic permeability based diagnostic test for the determination of the canine C-reactive protein concentration in undiluted whole blood

We describe an one-step 11-min magnetic permeability based two-site immunoassay for C-reactive protein (CRP) utilizing polyclonal anti-canine CRP antibody conjugated dextran iron oxide nanoparticles (79 nm) as superparamagnetic labels and polyclonal anti-canine CRP conjugated silica microparticles (15 to 40 mu m) as carriers. An inductance based magnetic permeability reader was used to detect the

Upregulated levels of human β-defensins in patients with seasonal allergic rhinitis after allergen-specific immunotherapy treatment.

BACKGROUND: Antimicrobial peptides (AMPs) are important actors in the innate immune system. One class of AMPs is the human β-defensins (HBDs), a group of small peptides with a broad spectrum of antimicrobial activities. Expression of HBDs is downregulated in different manifestations of allergic disease. In this study, we examine whether allergen-specific immunotherapy (ASIT) affects the nasal leve

Land degradation and mitigation in northern China. Evaluated from the biological production

Popular Abstract in Swedish De semi-arida regionerna i norra Kina är drabbade av många faktorer som påverkar miljön negativt, t.ex. ökenspridning, vind erosion, överbetning, uttömmande av naturresurser. Det redan hårda trycket på ekosystemen i dessa regioner har ökat sedan Kina införde marknadsekonomi. Reformerna sedan 1978 har lett till en snabb ökning av antalet betesdjur och en expansion av jorLand degradation is commonly perceived to be severe in many parts of semi arid China. The transition towards market economy since the 1978 reforms, have set marginal dry lands under added pressure in the form of increased livestock numbers and expanding cultivation on erosive soils. To evaluate land degradation since the reforms, this study focuses on mapping and analysing the biological productio

Sand Waves and Human Tides: Exploring Environmental Myths on Desertification and Climate-Induced Migration

In spite of the growing attention to climate-induced migration, a coherent understanding of the matter is lackingas any articulated governance strategy. Although such an impasse relates to the unprecedented socioecological processes involved, we argue that many of the challenges posed by climate-induced migration are not unique in the history of global environmental governance. Proceeding from thi

Sex Pheromone Evolution Is Associated with Differential Regulation of the Same Desaturase Gene in Two Genera of Leafroller Moths

Chemical signals are prevalent in sexual communication systems. Mate recognition has been extensively studied within the Lepidoptera, where the production and recognition of species-specific sex pheromone signals are typically the defining character. While the specific blend of compounds that makes up the sex pheromones of many species has been characterized, the molecular mechanisms underpinning

The sediments of Lake Logurinn - A unique proxy record of Holocene glacial meltwater variability in eastern Iceland

The full Holocene development of the large (8100 km(2)) Vatnajokull ice cap in Iceland with its many outlet glaciers is poorly known. The idea of an early deglaciation, leading to a glacier-free period in mid-Holocene, followed by the Neoglaciation is still the main concept for the glacial history in the North Atlantic region, including Iceland. We have examined a continuous sediment record from t

Variation at the Melanocortin 4 Receptor Gene and Response to Weight-Loss Interventions in the Diabetes Prevention Program

Objective: To assess associations and genotype x treatment interactions for melanocortin 4 receptor (MC4R) locus variants and obesity-related traits. Design and Methods: Diabetes prevention program (DPP) participants (N = 3,819, of whom 3,356 were genotyped for baseline and 3,234 for longitudinal analyses) were randomized into intensive lifestyle modification (diet, exercise, weight loss), metform

Novel antibody specificities targeting glycoprotein B of cytomegalovirus identified by molecular library technology

Antibodies provide some protection against cytomegalovirus-mediated disease. All aspects of antibody recognition of important viral antigens are however not fully appreciated. Glycoprotein B (gB), a key protein in the viral membrane, participates in viral infection and it is a component of prototype vaccines. By using combinatorial antibody library and selection technology, novel antibody specific