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Background:Transcriptomic profiles have shown promise as predictors of response to neoadjuvant chemotherapy in breast cancer (BC). This study aimed to explore their predictive value in the advanced BC (ABC) setting.Methods:In a Phase 3 trial of first-line chemotherapy in ABC, a fine needle aspiration biopsy (FNAB) was obtained at baseline. Intrinsic molecular subtypes and gene modules related to i
Central Skåne (Scania) in southern Sweden hosts evidence of extensive Jurassic volcanism in the form of mafic volcanic plugs and associated volcaniclastic deposits that entomb wellpreserved macro-plant and spore-pollen assemblages. Palynological assemblages recovered from the Höör Sandstone are of Hettangian-Pliensbachian age and those from the overlying lahar deposits are dated as Pliensbachian-e
Gastric cancer is a serious health problem worldwide. Although its incidence is decreasing, the five-year survival rate remains low. Thus, it is essential to identify new biomarkers that could promote better diagnosis and treatment of patients with gastric cancer. High-mobility group AT-hook 1 (HMGA1) is a non-histone, chromatin-binding protein that has been found overexpressed in several tumor ty
This dissertation is developed against the background of globalisation and the rise of a new type of instrument used to deal with the accompanying developments. These instruments are designated by the present dissertation as global framework agreements (GFAs). They constitute a written compromise, signed between global union federations and multinational enterprises, setting rights-based minimum s
Our paper about the impacts of the Laschamps Geomagnetic Excursion 42,000 years ago has provoked considerable scientific and public interest, particularly in the so-called Adams Event associated with the initial transition of the magnetic poles. Although we welcome the opportunity to discuss our new ideas, Hawks’ assertions of misrepresentation are especially disappointing given his limited examin
This study explores the emergence of a new entrepreneurship phenomenon (digital social entrepreneurship) as a result of the collaboration among many agents (N-Helix), given the government’s limited capacity to respond to the stakeholders’ needs satisfaction related to an exogenous event (e.g., the COVID-19 pandemic). Our theory development is based on three ongoing academic debates related to (a)
Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. Methods: This was a longitudinal cohort study using d
Many populations of water fleas (Daphnia) are exposed to algal blooms dominated by microcystin-producing cyanobacteria. However, the severity of these effects on Daphnia fitness remain poorly understood in natural populations. We investigated seasonal changes in body size, reproduction and survival of D. longispina individuals from five eutrophic lakes in southern Sweden. We tested whether individ
The STRIPAK complex has been linked to a variety of biological processes taking place during embryogenesis and development, but its role in cancer has only just started to be defined. Here, we expand on previous work indicating a role for the scaffolding protein STRIP1 in cancer cell migration and metastasis. We show that cell cycle arrest and decreased proliferation are seen upon loss of STRIP1 i
Doktorand Kontaktinformation E-post: heraclitos [dot] muhire [at] soclaw [dot] lu [dot] seOrganisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsHeraclitos Muhires profil i Lunds universitets forskningsportalAndra roller Forskningsassistent Rättssociologiska institutionenForskningsområdenSvängdörrar mellan offentlig sektor och näringslivArbetskraftsexploatering av migrantarbetareAcce
https://www.soclaw.lu.se/heraclitos-muhire - 2026-06-26
This study tests whether the Ricardian Equivalence Hypothesis holds in Sweden when the private sector faces an intertemporal budget constraint skewed by the media narrative. Time series analysis of cointegrated vector autoregressive processes is utilized to identify Ricardian consumer behavior in three different models, in order to find differences in consumer behavior when media narrative bias is
Workplace social media monitoring has become increasingly prevalent, raising critical concerns about privacy and fairness in employee-employer relationships. This thesis investigated the associations between the Big Five personality traits and employee perceptions of social media monitoring in the workplace. Using a quantitative research design, the study examined how openness, conscientiousness,
From being primarily associated with the political climate of the United States, pluralism as a political mind-set with its focus on interest groups as important political entities has become increasingly descriptive of the European Union as well. Seeking to investigate the theoretical aspects of pluralism, the purpose of this essay is to analyse and discuss whether the European setting might have
The climate crisis is not only affecting the physical world, but individuals’ mental health. The concept of ecoanxiety has reached major attention in the public discourse and more individuals report psychological consequences as a result of climate change. The call for action is urgent, but what are individuals doing to prevent further harm to the planet? Does the experience of ecoanxiety leave th
IntroductionIn policy and political debate, media and information literacy (MIL) is increasingly framed as a civic responsibility and a strategic response to the contemporary ‘information crisis’, marked by disinformation and digital insecurity. This positions MIL as essential to democratic resilience and national security but risks excluding individuals who lack the resources or capacities to mee
