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Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation

Despite improvements, lung transplantation remains hampered by both a scarcity of donor organs and by mortality following primary graft dysfunction (PGD). Since acute respiratory distress syndrome (ARDS) limits donor lungs utilization, we investigated cytokine adsorption as a means of treating ARDS donor lungs. We induced mild to moderate ARDS using lipopolysaccharide in 16 donor pigs. Lungs were

Increased expression of ORMDL3 in allergic asthma : a case control and in vitro study

BACKGROUND: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is the ORMDL3 gene confirmed in several GWA studies in several paediatric populations.OBJECTIVES: The purpose of this study was to analyse ORMDL3 variants and expression in childhood asthma in the Polish population.MATERIALS AND METHODS: In the study we included 416

Framväxten av universell utformning – en kulturomdaning

Per-Olof Hedvall ger en inblick i hur universell design startade och hur det tankeskiftet tar klivet in i arbetslivet med UUA. Om hur vi kan göra arbetslivet mer tillgängligt från början och minska risken för kategoriseringar och särbehandling.

Pre-service teachers’ explanations of division by zero and denseness of the number line.

Students’ beliefs about division by zero and numbers on the number line werestudied through explanations of the concepts in questionnaires and interviewsduring their teacher education to become primary school teachers in the years4–6. The concepts were chosen for students’ proven cognitive challenges incoping with them, with the aim to add to the existing knowledge in terms ofspecific and general

The Inverted Wish : Towards Walter Benjamin’s Notion of Time

Walter Benjamin’s complex notion of time, permeating much of his historical, political, and cultural-critical thought, has been the subject of considerable discussion. In particular, the interaction between the two opposing categories of historical time and messianic time poses a great difficulty: how do messianic moments of cessation act within the homogeneous continuum of history? To propose one

Functional and molecular profiling of hematopoietic stem cells during regeneration

Hematopoietic stem cells (HSCs) enable hematopoietic stem cell transplantation (HCT) through their ability to replenish the entire blood system. Proliferation of HSCs is linked to decreased reconstitution potential, and a precise regulation of actively dividing HSCs is thus essential to ensure long-term functionality. This regulation becomes important in the transplantation setting where HSCs unde

The Oseberg ship. Long-term physical-mechanical monitoring in an uncontrolled RH exhibition environment. : analytical results and hygromechanical modeling

A continuous monitoring system was installed on the Oseberg ship, a large Viking Age archaeological wooden object (oak), in order to determine the material response to the uncontrolled conditions at the Viking Ship Museum, Oslo, Norway. Four areas have been monitored since July 2009, two boards on the ship and two samples free to deform (recent oak and a sample removed from the ship). Results, rep

Cyclic Structure Induced by Load Fluctuations in Adaptive Transportation Networks

Transport networks are crucial to the functioning of natural systems and technological infrastructures. For flow networks in many scenarios, such as rivers or blood vessels, acyclic networks (i.e., trees) are optimal structures when assuming time-independent in- and outflow. Dropping this assumption, fluctuations of net flow at source and/or sink nodes may render the pure tree solutions unstable e

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This article presents readings of three French novels from the nineteenth century, namely Balzac's La Peau de chagrin, Huysmans' À rebours and Octave Mirbeau's Le Jardin des supplices. It examines issues of representation and meaning in relation to debt narratives and the use of bodies as a motif in relation to debt, and it argues that, in these novels, literary language and monetary representatio

Mergers of semi-autonomous central agencies: The Swedish trajectory and the case of the Swedish Social Insurance Agency

As the number of autonomous executive agencies increases, some countries have started merging agencies, thereby aiming to reduce fragmentation and cut public spending. These mergers have passed conspicuously unnoticed in research. In Sweden, the current wave of agency mergers started in the 1990ies. This paper aims to (1) give a background to the Swedish trajectory with agency mergers and to (2),

A case study of fires in structural elements

Several severe fires in structural elements, or so-called "structural fires", have occurred in Sweden in recent years. In order to study this phenomenon, a dozen fires in structural elements have been studied in a recent project. This paper provides a description of the characteristics of "structural fires" and examples of how such events can be managed and limited. Constructional fire protection,