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Fenestrated and Branched Endovascular Aortic Arch Repair Outcomes in Female Patients : A Retrospective Multicentre Analysis

OBJECTIVE: Data on females managed with fenestrated or branched endovascular aortic arch repair (FB-Arch) are limited. This study aimed to present the 30 day and follow up outcomes of FB-Arch in female patients.METHODS: A retrospective analysis (1 January 2011 to 31 March 2024) among four European aortic centres was conducted according to STROBE guidelines. Consecutive female patients managed with

Sustained Remission in Patients With Rheumatoid Arthritis Receiving Triple Therapy Compared to Biologic Therapy : A Swedish Nationwide Register Study

Objective: To compare the real-life effectiveness of biologic therapy (a biologic disease-modifying antirheumatic drug plus methotrexate [MTX]) versus triple therapy (MTX plus sulfasalazine plus hydroxychloroquine/chloroquine) for sustained remission of rheumatoid arthritis (RA). Methods: RA patients who were registered in the nationwide Swedish Rheumatology Quality Register between 2000 and 2012

Disentangling white-matter damage from physiological fibre orientation dispersion in multiple sclerosis

Multiple sclerosis leads to diffuse damage of the central nervous system, affecting also the normal-appearing white matter. Demyelination and axonal degeneration reduce regional fractional anisotropy in normal-appearing white matter, which can be routinely mapped with diffusion tensor imaging. However, the standard fractional anisotropy metric is also sensitive to physiological variations in orien

Nighttime Bracing or Exercise in Moderate-Grade Adolescent Idiopathic Scoliosis A Randomized Clinical Trial

IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activ

Oncologic Outcomes of Incidental Versus Biopsy-diagnosed Grade Group 1 Prostate Cancer : A Multi-institutional Study

Background and objective: Patients diagnosed with grade group (GG) 1 prostate cancer (PCa) following treatment for benign disease (“incidental” PCa) are typically managed with active surveillance (AS). It is not known how their outcomes compare with those observed in patients diagnosed with GG1 on biopsy. We aimed at determining whether long-term oncologic outcomes of AS for patients with GG1 PCa

Laparoscopic lavage vs primary resection for acute perforated diverticulitis : The SCANDIV randomized clinical trial

IMPORTANCE: Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection procedures. OBJECTIVE: To compare the outcomes from laparoscopic lavage with those for colon resection for perforated diverticulitis. DESIGN, S

User acceptance of a personalised home lighting system based on wearable technology

Light/dark cycles play an essential role in people's performance, mood and daily rhythm. This study aimed to evaluate an early prototype of a personalised home lighting system including body-worn loggers. A convenience sample (N = 28) wore the devices for 23 h in the field and were given a demonstration of the lighting system components. Participants reported on questionnaires their acceptance of

Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia : a meta-analysis

Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,

Quantitative assessment of the relationship between land use/land cover (LULC), topographic elevation and land surface temperature (LST) in Ilorin, Nigeria

The urbanization of landscapes and the increase in impervious land cover materials is known to cause significant changes in the landscape's thermal properties, typically leading to urban heat island (UHI). Although previous studies have investigated the impacts of land cover land use (LULC) and other factors on the urban land surface temperature (LST), the results of such studies are mixed. For in

Uptake of cervical cancer screening and its predictors among women of reproductive age in Gomma district, South West Ethiopia : a community-based cross-sectional study

Background: Cervical cancer is a public health challenge despite the available free screening service in Ethiopia. Early screening for cervical cancer significantly improves the chances of successful treatment of pre-cancers and cancers among women of reproductive age. Therefore, this study aimed to assess the uptake of screening and identify the factors among women of reproductive age. Methods: A

Seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania

Background: Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The majority of infected people, including healthcare workers are unaware of their status. This study is aimed to determining seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania. Methods: This cross-sectio

Evaluating effect modification by HIV testing history to understand the mechanisms behind the impact of announcing HIV self-testing availability in a clinic system in Kenya

Background: In sub-Saharan Africa, truckers and female sex workers (FSWs) have high HIV risk and face challenges accessing HIV testing. Adding HIV self-testing (HIVST) to standard of care (SOC) programs increases testing rates. However, the underlying mechanisms are not fully understood. HIVST may decrease barriers (inconvenient clinic hours, confidentiality concerns) and thus we would expect a gr

Parameter Identification For Inter Turn Fault Detection In Permanent-Magnet Synchronous Motors Using Stator Flux Linkage DC Offset Monitoring

The parameters of PMSM with inter-turn fault are identified using a time-stepping finite element method (FEM). Analytical expressions (AE) uses the estimated parameters for fault analysis similar to FEM analysis. The fault waveforms, terminal voltages, obtained from the AE models are used for inter turn fault (ITF) detection, using Stator Flux Linkage DC offset (SFDO). A comparison is made between

On Metrics for Information Value Quantification

In this paper, we aggregate, analyze, and exemplify several metrics for the information value. The metrics vary by absolute value, normalizations, or full probabilistic quantification. The normalization of the information value encompasses the division by (1) the expected and maximized utility of the base scenario (usually without additional information), (2) by the system performance, or (3) by t

Radome Diagnostics: utilizing Source Reconstruction based on Surface Integral Representations

Popular Abstract in Swedish Elektromagnetiska fält finns idag överallt och är en förutsättning för att det moderna samhället ska fungera. Utan att fundera närmare på det, använder vi oss ständigt av de elektromagnetiska fältens förmåga att trådlöst överföra information och energi. Några exempel är; uppvärmning av mat i mikron och på induktionshällen, samtal i mobiltelefonen, uppdatering av status In this thesis, an inverse source reconstruction method with great potential in radome diagnostics is presented. A radome is a cover that encloses an antenna in order to protect it from environmental influences. Radome diagnostics are acquired in the design process, the delivery control, and in performance verification of repaired and newly developed radomes. A measured near or far field may indic

On the mechanisms that limit oxygen uptake during exercise in acute and chronic hypoxia: role of muscle mass

Peak aerobic power in humans ((V) over dot(O2), peak) is markedly affected by inspired O-2 tension (F-IO2). The question to be answered in this study is what factor plays a major role in the limitation of muscle peak. (V) over dot(O2) in hypoxia: arterial O-2 partial pressure (P-a,(O2)) or O-2 content (C-a,C-O2)? Thus, cardiac output (dye dilution with Cardio-green), leg blood flow (thermodilution

Deep Brain Stimulation in Parkinson's disease and essential tremor Outcome and experiences from patients' and spouses' perspectives

Popular Abstract in Swedish Den här avhandlingen har behandlingsresultaten av permanent djupelektrod stimulering i hjärnan (Deep Brain Stimulation, DBS) undersökts ur såväl symptomminsknings som patients och närståendes perspektiv. DBS behandling innebär att en elektrod med fyra poler opereras in i hjärnan genom ett litet hål i skallbenet, och den kopplas till pulsgivardosa. Hela systemet är doltThe treatment related effects and personalized goal fulfilment of Deep Brain Stimulation (DBS) have been assessed in studies with different designs. The brain targets included the thalamus for medically intractable tremor in Parkinson's disease (PD) or essential tremor (ET) and the subthalamicus for reducing hypo-, bradykinesia, tremor, rigidity and dystonia in PD. A Swedish multi-center study sh