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Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients

Objective: Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) has previously shown alterations in cerebral perfusion in patients with systemic lupus erythematosus (SLE). However, the results have been inconsistent, in particular regarding neuropsychiatric (NP) SLE. Thus, we investigated perfusion-based measures in different brain regions in SLE patients with and without NP invo

"En helt annan upplevelse" : Ljudbokens band till sina läsare

Audiobooks have in recent years become widely popular. The format accordingly impacts how many contemporary readers use and experience literature. The article examines this tendency, departing from Rita Felski’s theoretical conceptualizations of uses of literature (Felski 2008). Felski represents a new attention within literary studies toward the ways in which so-called lay readers use, experience

Characterizing Uncertainty in the Visual Text Analysis Pipeline

Current visual text analysis approaches rely on sophisticated processing pipelines. Each step of such a pipeline potentially amplifies any uncertainties from the previous step. To ensure the comprehensibility and interoperability of the results, it is of paramount importance to clearly communicate the uncertainty not only of the output but also within the pipeline. In this paper, we characterize t

Perceived Barriers to Decision Quality in Three Swedish Public Authorities

Barriers to decision quality were reported by 473 administrative officers and investigators in three Swedish national public authorities: the Tax Agency, Social Insurance Agency, and Police Authority. In line with previous research, we assumed that limited possibilities to plan one’s work would hinder decision quality. Both disruption of workflow and high workload were reported to inhibit work pla

Gendered knowledges in schools – trans* young people’s experiences and schools’ strategies

What knowledges and understandings of gender are done and producedin schools in Sweden today? Through interviews with trans* young peopleand young adults, this study analyzes schools and adults’ abilities and knowledges to understand and meet the needs of trans* students and to address cisnormative structures in school. The participants’ narratives give a richand complex image of what it can mean

Controlling Evolutionary Dynamics in Networks : A Case Study

Due to their wide adaptability to different application fields spanning from opinion dynamics to biology, the analysis of evolutionary dynamics is a compelling problem in the science of networks and systems. In this paper, we deal with controlled evolutionary dynamics in networks. We discuss a novel approach to model these phenomena, which enables us to estimate the duration of the process dependi

The prognostic performance of lactate in out of hospital cardiac arrest, a post hoc analysis of the TTM-trial

The purpose of this studywas to investigate the prognostic value of lactate at admission, 12-h lactate and 12-h lactate clearance for 30-day survival in comatose patients admitted after out of hospi tal cardiac Arrest (OHCA). Although measures of lactate have been successfully implemented in sepsis and trauma care, most OHCA studies are biased due to design and the results are conflicting. This is

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as