Filtyp
The cohesin ring, which is composed of the Smc1, Smc3, and Scc1 subunits, topologically embraces two sister chromatids from S phase until anaphase to ensure their precise segregation to the daughter cells. The opening of the ring is required for its loading on the chromosomes and unloading by the action of Wpl1 protein. Both loading and unloading are dependent on ATP hydrolysis by the Smc1 and Smc
This paper attempts to assemble a conceptual framework for understanding to what extent an energy technology is simply a way of putting nature to work, and to what extent it is a way of putting other segments of global society to work. The turn to fossil energy reversed the relation between energy and space, as fossil fuels henceforth propelled new transport technologies that provided access to in
In this contribution a practical and rational decision-making approach is presented to be applied for common bridges typically managed by public authorities. The authors have developed a model with the intention to be applicable for practical cases for common bridges in the daily work of bride operators responsible for a large number of assets, yet still maintain the principles of more generic fra
As urban systems continue to grow worldwide, urban peripheries increase in number and typologies, which makes their planning a challenge for sustainable development. The aim of this article is to explore approaches and challenges related to the application of sustainable planning to urban peripheries. We reviewed the content of 102 papers related to sustainable planning in urban peripheries by app
A key task in the ESMERALDA project dealt with identifying appropriate case studies to test the ‘flexible methodology’ in its different stages of development. Case studies consist of working examples in which mapping and assessment of ecosystem services were applied to address specific decision-making problems. Testing is understood as an iterative process of co-learning that involves project part
Question: How does reproductive timing in annual social insects evolve under intraspecific exploitation competition and in response to a changing environment? The latter includes shifts in resource abundance, mortality, season length, and resource peak timing, factors often associated with climate change. Background: Climate and land use are changing. Evolutionary ecology must learn to predict how
Screening 60-yr-old men for renal cancer using ultrasound may be cost effective, and further research into this topic is of value to society. The prevalence of renal cancer by age/sex and the stage shift associated with screening are key research priorities.
A new approach to understanding the interaction between cortical areas is provided by a mathematical analysis of biased competition, which describes many interactions between cortical areas, including those involved in top-down attention. The analysis helps to elucidate the principles of operation of such cortical systems, and in particular the parameter values within which biased competition oper
Bokanmälan av Yishai Beer: Military Professionalism and Humanitarian Law. The Struggle to Reduce the Hazards of War. New York NY: Oxford University Press, 2018. ISBN 978-0-19-088114-6
The aim of this work is the development of a thermodynamically consistent fully coupled thermo-viscoplastic material model for metals undergoing finite deformation and large temperature changes.The deformation gradient is supposed to be decomposable into a thermal, an elastic, and a plastic part, where purely volumetric thermal expansion and isochoric plastic distortion is assumed. The model is ba
Pavement data collection is the most expensive and time consuming component of Pavement Management System (PMS). Thus, possible methods of minimizing the need of such data might be critical in reducing pavement condition monitoring costs. Also the ability to relate pavement performance prediction models (frequently roughness based) to hot mix asphalt field performance models (distress based) provi
The rapid accumulation of ancient human genomes from various areas and time periods potentially enables the expansion of studies of biodiversity, biogeography, forensics, population history, and epidemiology into past populations. However, most ancient DNA (aDNA) data were generated through microarrays designed for modern-day populations, which are known to misrepresent the population structure. P
Sustainability challenges are defined by their complex and multifaceted interactions between nature and society and contention as to how and where to direct problem-solving efforts. This chapter presents four different approaches that exist for framing sustainability challenge areas that are introduced and worked with by students in LUMES International Master Programme in Environmental Studies and
Background: Brief screening instruments focusing on autism spectrum disorder (ASD) that can be administered in primary care are scarce; there is a need for shorter and more precise instruments. The Autism-Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated for ASD reporting excellent validity. This study aims to determine the psychometric properties of each item in
Partially premixed combustion (PPC) is one of several advanced combustion concepts for the conventional diesel engine. PPC uses a separation between end of fuel injection and start of combustion, also called ignition dwell, to increase the mixing of fuel and oxidizer. This has been shown to be beneficial for simultaneously reducing harmful emissions and fuel consumption. The ignition dwell can be
There is a growing interest in organized self-help housing (OSHH) from both authoriti es and Non Governmental Organizati ons (NGOs) working in the housing sector due to the magnitude of housing problems in developing countries and the challenge of achieving sustainable humansett lements. This paper focuses on the experiences of two NGOs, FUPROVI in Costa Rica and SADEL in Sweden, in facilitati ng
