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Myelin-sensitive quantitative (q) MRI techniques including MT (3D FLASH) and DTI (single-shot STEAM) are of growing importance to study white matter (WM) disorders in childhood. Cerebral folate transport deficiency is an inherited, treatable WM disorder with hypomyelination, developmental regression, movement disturbances, and epilepsy. One patient with this diagnosis and severe phenotype was trea

This article is contributing to the future of copyright law debate by exploring the recently harmonised originality standard in the EU copyright law and its suitability to a creative sharing community of Wikipedia. It shows that the “free creative choices” and “author’s personal” touch criteria established by the CJEU might be unsuitable not only because of practical concerns, but also because the

Inflammation has been proposed to play a role in the generation of depressive symptoms. Previously, we demonstrated that patients with major depressive disorder (MDD) have increased plasma levels of the soluble form of the urokinase receptor (suPAR), a marker for low-grade inflammation. The aim of this study was to test the hypothesis that acute exercise would induce inflammatory response characte

Presenterar Crusenstolpes erfarenheter av Lund och Lunds universitet med fokus på hans samtidsroman Tvenne äktenskap (1847).

Background: The integration of first- and second-generation bioethanol processes has the potential to accelerate the establishment of second-generation bioethanol on the market. Cofermenting pretreated wheat straw with a glucose-rich process stream, such as wheat grain hydrolysate, in a simultaneous saccharification and fermentation process could address the technical issues faced during the biolo

During the last two decades, survival rates after cardiac arrest have increased while the fraction of patients surviving with a severe neurological disability or vegetative state has decreased in many countries. While improved survival is due to improvements in the whole chain of survival, improved methods for prognostication of neurological outcome may be of major importance for the lower disabil

The use of public demand to spur innovation has recently seen a very significant in-crease in political support. Such a policy promises improvement of public services on all state levels, combined with a contribution to innovation dynamics. It has become clear that strong efforts are needed to mobilise procurement at all state levels for inno-vative markets. These efforts need to be based on a bet

Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and

The aim of this paper is to critically analyse so-called ‘successful’ low-carbon energy transitions under the energy justice magnifying glass. We focus on two case studies that have been arguably referred to as successful local energy transitions in the literature: Samsø (Denmark) and Feldheim (Germany). The study examines community perspectives and causal inferences about perceived energy (in)jus

This article examines the two French-language novels by the Franco-Chinese migrant writer François Cheng, Le Dit de Tianyi (1998) and L'éternité n'est pas de trop (2002), and proposes to conceptualize them as two novelistic models of cultural translation. Cheng's engagement with, and departure from, canonical Western novelistic models such as Proust's A la recherche du temps perdu in Le Dit reveal

Moving toward the open innovation (OI) model requires multifaceted transformations within companies. It often involves giving away the tools for product development or sharing future product directions with open tools ecosystems. Moving from the traditional closed innovation model toward an OI model for software development tools shows the potential to increase software development competence and

The need for modelling of materials behaviour under various mechanical conditions is driven by the evolution of computer capacity and the ability of scientists to address complex mechanical problems. Reliable models for materials behaviour, including accurate numerical values of parameters, are necessary for a continued beneficial development of the computational side of solid mechanics. High rate

In "Intentional action and side-effects in ordinary language” (2003), Joshua Knobe reported an asymmetry in test subjects’ responses to a question about intentionality: subjects are more likely to judge that a side effect of an agent’s intended action is intentional if they think the side effect is morally bad than if they think it is morally good. This result has been taken to suggest that the co