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Table-Top Ultrafast X-Ray Microcalorimeter Spectrometry for Molecular Structure

This work presents an x-ray absorption measurement by use of ionizing radiation generated by a femtosecond pulsed laser source. The spectrometer was a microcalorimetric array whose pixels are capable of accurately measuring energies of individual radiation quanta. An isotropic continuum x-ray spectrum in the few-keV range was generated from a laser plasma source with a water-jet target. X rays wer

Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems

This article discusses the role of the protein corona in delivery systems with tagged nanoparticles and how knowledge of the protein corona can help in optimizing delivery. The basic question is whether and how the binding of proteins and other biomolecules at the nanoparticle surface interfere with the interaction between a tag and its receptor. This is an interesting problem in many respects, bu

Weight loss is effective for symptomatic relief in obese subjects with knee osteoarthritis independently of joint damage severity assessed by high-field MRI and radiography

Objective: With an increasing prevalence of older and obese citizens, the problems of knee osteoarthritis (KOA) will escalate. Weight loss is recommended for obese KOA patients and in a majority of cases this leads to symptomatic relief. We hypothesized that pre-treatment structural status of the knee joint, assessed by radiographs, 1.5 T magnetic resonance imaging (MRI) and knee-joint alignment,

Country of birth, parental background and self-rated health among adolescents: A population-based study.

Aims: The aim of this study was to investigate differences according to country of birth and parental country of birth, in relation to poor self-rated health (SRH), in Swedish adolescents. Methods: The Scania public health survey among children and adolescents, conducted in 2012, is a cross-sectional study including most pupils in grade 9 (15 years old), including in 32 of 33 municipalities. The p

A simple and sensitive method for lactose detection based on direct electron transfer between immobilised cellobiose dehydrogenase and screen-printed carbon electrodes

A rapid and simple approach of lactose analysis is proposed based on 3rd generation amperometric biosensors employing cellobiose dehydrogenase (CDH) from Trametes villosa or Phanerochaete sordida immobilised on screen-printed carbon electrodes (SPCEs). After optimisation of the working conditions of the biosensors - pH of the carrier buffer, flow rate and applied potential - the sensors were able

Coherence and population dynamics of chlorophyll excitations in FCP complex: Two-dimensional spectroscopy study.

Energy transfer processes and coherent phenomena in the fucoxanthin-chlorophyll protein complex, which is responsible for the light harvesting function in marine algae diatoms, were investigated at 77 K by using two-dimensional electronic spectroscopy. Experiments performed on femtosecond and picosecond timescales led to separation of spectral dynamics, witnessing evolutions of coherence and popul

Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study)

Objective To examine use of magnetic resonance imaging (MRI) of knees with no radiographic evidence of osteoarthritis to determine the prevalence of structural lesions associated with osteoarthritis and their relation to age, sex, and obesity. Design Population based observational study. Setting Community cohort in Framingham, MA, United States (Framingham osteoarthritis study). Participants 710 p

Density-Functional Theory for Strongly Correlated Bosonic and Fermionic Ultracold Dipolar and Ionic Gases

We introduce a density functional formalism to study the ground-state properties of strongly correlated dipolar and ionic ultracold bosonic and fermionic gases, based on the self-consistent combination of the weak and the strong coupling limits. Contrary to conventional density functional approaches, our formalism does not require a previous calculation of the interacting homogeneous gas, and it i

Ultra Long-Lived Radiative Trap States in CdSe Quantum Dots

Surface states and traps play an important role in the photophysics of colloidal quantum dots. These states typically lead to large red-shifted photoluminescence. We have used steady-state and time-resolved spectroscopic techniques to investigate the nature of the traps and their lifetimes in colloidal CdSe quantum dots. We conclude that at least two different types of traps contribute to the phot

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

Background Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke a

Effective interactions between soft-repulsive colloids: Experiments, theory, and simulations.

We describe a combined experimental, theoretical, and simulation study of the structural correlations between cross-linked highly monodisperse and swollen Poly(N-isopropylacrylamide) microgel dispersions in the fluid phase in order to obtain the effective pair-interaction potential between the microgels. The density-dependent experimental pair distribution functions g(r)'s are deduced from real sp

1H NMR diffusometry study of water in casein dispersions and gels

The self-diffusion coefficients of water in casein solutions and gels were measured using a pulsed-gradient spin-echo nuclear magnetic resonance technique (PGSE NMR). The dependence of the self-diffusion coefficient of water on the concentration and structure-of casein is reported. The results were analyzed using a cell model. It was found that the water self-diffusion coefficient is insensitive t

Postmodern vitalism: från D'Arcy Thompson till Mandelbrot

Man har gett namnet ”vitalister” till de tänkare som tillskriver den levande materian en särskild status. Den särskilda statusen kräver vissa uppoffringar. Vitalismen är tvungen att erkänna ett orsaksbegrepp som avviker markant från det dominerande mekanistiska modellen i det modernistiska programmet. Den vitala ”kraften” eller ”principen”, agerar genom den organiska vävnaden för att orsaka den rö

Iodinated SnO2 quantum dots : A facile and efficient approach to increase solar absorption for visible-light photocatalysis

Efficient visible-light-driven photocatalysis can be achieved over conventional wide band gap semiconductor, in which iodinated SnO2 quantum dots (QDs) are synthesized via hydrolysis of crystalline SnI4 in the absence of any additives or templates. The formation of SnO2 QDs reveals a wide preparation window and a very fast growth rate in minute scale. The iodine species may only exist on the surfa