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C1q is the initiator of the classical complement pathway and opsonizes apoptotic cells to facilitate phagocytosis. Deficiency of C1q is the strongest known risk factor for development of systemic lupus erythematosus (SLE)a, which appears to be related to ensuing impaired clearance of apoptotic material. The objective of the current study was to investigate new ligands for C1q on the surface of apo
Studying how animals interface with a virtual reality can further our understanding of how attention, learning and memory, sensory processing, and navigation are handled by the brain, at both the neurophysiological and behavioural levels. To this end, we have developed a novel vision-based tracking system, FicTrac (Fictive path Tracking software), for estimating the path an animal makes whilst rot
Background: The aims of this study were to establish the diagnostic accuracy of the European Cross-Cultural Neuropsychological Test Battery (CNTB) for dementia in different ethnic populations in Western Europe, to examine its ability to differentiate cognitive impairment profiles for dementia subtypes, and to assess the impact of demographic variables on diagnostic properties. Methods: The study w
Purpose: This paper aims to explore how the ownership transfer from a highly industrialised country to less industrialised countries influences consumers’ brand perceptions. Design/methodology/approach: Three acquisition cases of premium car brands (Jaguar, Land Rover and Volvo) are investigated using qualitative data from online brand communities. Findings: When country of ownership (COOW) for br
Performing risk assessments for hierarchical, multi-functional systems, such as a municipality, is an activity that requires input from a multitude of actors. In such systems risk assessments can be performed at many system levels and support different types of decisions. For issues that are constrained to a specific sub-system, such as a municipal department, decisions can be preferably taken at
This paper presents the case study of a newly constructed 1600 m2 kindergarten building in Oslo, Norway. The building has been designed within the framework of the Norwegian Research Council Project LowEx, which aims at engineering solutions to achieve a seasonal coefficient of performance (SCOP) of 6–10 for heating, a seasonal energy efficiency ratio (SEER) of 80–100 for cooling, and an 80% reduc
Many reinforced concrete bridges in Europe and around the world are damaged by reinforcement corrosion and the annual maintenance costs are enormous. It is therefore important to develop reliable methods to assess the structural capacity of corroded reinforced concrete structures and avoid unnecessary maintenance costs. Although there are advanced models for determining the load carrying capacity
Background: It is important to quantify a static posture to evaluate the need for and effectiveness of interventions such as physical management, physiotherapy, spinal orthosis or surgical treatment on the alignment of body segments. Motion analysis systems can be used for this purpose, but they are expensive, require a high degree of technical experience and are not easily accessible. A simpler m
En allt mer konkurrensinriktad marknad har ökat behovet för företag att fokusera på sin kärnkompetens. Givet denna utveckling har större nätverk med fler involverade parter vuxit fram, vilket lett till att fler företag börjat vända sig till en fjärde part. Fjärdepartslogistik innefattar en komplex integrering av försörjningskedjans alla komponenter och ett för kunden större överlåtande av sin verk
Cross-functional teams and meetings are recurrent structuring tools in contemporary knowledge organisations. They are recommended as solutions to enhance innovation and creativity. Current research gathers a myriad of reference to the benefits of such tools, but studies of their potential negative effects remain limited. This paper is specifically concerned with the effect of interdisciplinary tea
The purpose of the report is to study the yellow cycle route in the city of Lund and investigate the inadequacies that could be found on today's route. The yellow cycle route goes from Dalby in the south to Gunnesbo in the north. The method used to answer the questions of this report is literature study and a technical inventory. The analysis of the studied route is based on Lund’s cycle strat
Value at Risk (VaR) is a popular measurement for valuing the risk exposure. Correct estimates of VaR are essential in order to properly be able to monitor the risk. This thesis examines a copula approach for estimating VaR for portfolios of commodities. The predictions are made from a semi- parametric model with Monte Carlo methods. The underlying model is constructed by choosing the best fit from
The many-body problem in quantum mechanics always presents new challenges and ways to discover new properties of existing materials. The difficulty (if not the impossibility) to solve the many-body problem analytically makes the numerical methods an appealing approach. Here we consider a Python code, which is under development to become an open-source tool to perform studies of finite lattice syst
Acquired hemophilia A (AHA) is an autoimmune disease caused by an autoantibody to factor VIII. Patients are at risk of severe and fatal hemorrhage until the inhibitor is eradicated, and guidelines recommend immunosuppression as soon as the diagnosis has been made. The optimal immunosuppressive regimen is unclear; therefore, data from 331 patients entered into the prospective EACH2 registry were an
Abstract in UndeterminedPurpose - The purpose of this paper is to describe and analyse ways of organizing integrated care for older persons in Sweden during the past decade. Design/methodology/approach - The data consist of 62 cases of development work, described in official reports. A meta-analysis of cases was performed, including content analysis of each case. A theoretical framework comprising
Objectives To compare different chronic obstructive pulmonary disease (COPD) cost-effectiveness models with respect to structure and input parameters and to cross-validate the models by running the same hypothetical treatment scenarios. Methods COPD modeling groups simulated four hypothetical interventions with their model and compared the results with a reference scenario of no intervention. T
