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BACKGROUND: Pesticides play a crucial role in pest control; however, exposure remains high, particularly among smallholder farmers in low-income and middle-income countries (LMICs) with little access to pesticide safety training. This study aimed to provide comparative biomarker-based evidence from Latin America and Africa and identify actionable determinants of exposure to inform context-specific

PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo

Despite recommendations to use oral lipid-lowering therapies (LLT) in secondary prevention of atherosclerotic cardiovascular disease, numerous studies have shown substantial under-utilization. We assessed long-term persistence and dynamics of adherence to oral LLTs in patients after their first ever myocardial infarction (MI) in Sweden. A total of 83,407 patients with a MI (2010–2017) and who were

Background: Cardiovascular risk factor control reduces the risk of recurrent events after acute coronary syndrome (ACS). Long-term post-ACS management is poorly studied. Objectives: To assess frequency of low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP) monitoring and target achievement during 3 years post-ACS. Methods: Data from all patients hospitalized for ACS in Up

Purpose: The purpose of this paper is to investigate the heat and mass transport characteristics in microchannel reactors with non-uniform catalyst distributions. Design/methodology/approach: A two-dimensional model is developed to study the heat and mass transport characteristics in microchannel reactors. The heat and mass transport processes in the microchannel reactors with non-uniform catalyst

OBJECTIVE: To clarify, using an extended adoption design, the sources of parent-offspring transmission for anxiety disorder (AD) and its major subforms and their familial cross-generational relationship with major depression (MD). METHODS: Offspring (born 1960-1992) and their parents, from six family types (intact, not-lived-with biological father or mother, lived-with step-father or step-mother,

PURPOSE: To evaluate vertical acceleration, vector magnitude, non-wear time, valid day classifications and valid period classifications, in the data processing phase when using the ActiGraph GT3X accelerometer in non-ambulant children and adolescents with cerebral palsy (CP).MATERIAL AND METHODS: Accelerometer data retrieved from 33 non-ambulant children and adolescents (4-17 years) with CP, were

Objectives: We aimed to explore the association between various physiological factors and pyelonephritis in parous women. Methods: Swedish nationwide registers were used to identify 1,073,467 parous women aged 15-50 years. The study period began in 1997 and ended in 2018, or at the first incidence of pyelonephritis, death, or emigration. Cox proportional hazards methods were used to determine haza

BACKGROUND: Studies in men of European ancestry suggest prostate-specific antigen (PSA) as a marker of early prostate cancer (PCa) development that may help to risk-stratify men earlier in life.METHODS: We examined PSA levels in men measured up to 10+ years before a PCa diagnosis in association with PCa risk in 2,245 cases and 2,203 controls of African American, Latino, Japanese, Native Hawaiian,

I will describe principles and advantages of semiconductor nanowires as applied to fabrication of light-emitting diodes for display and solid state lighting applications as well as for the realization of nanowire array solar cells.

One common goal of sample analysis is to provide structural, compositional, or functional data in order to improve production parameters. One instrument specialized in such structural and compositional analysis with a high spatial resolution is the transmission electron microscope (TEM). The high-end microscopes have the capability of sub-Ångström resolution and compositional quantification and di

Constitutive activation of interferon signaling pathways has been reported in colorectal cancer (CRC), leading to a strong CD8+ T cell response through stimulation of NLRC5 expression. Primed CD8+ T cell expansion, however, may be negatively regulated by PD-L1 expression. Additionally, aberrant PD-L1 expression enables cancer cells to escape the immune attack. Our study aimed to select potential r

Whilst health consequences of being locked-in at the workplace have been documented in several research studies, it is largely unknown how work characteristics and their changes over time relate to risks for becoming locked-in at a certain workplace. Accordingly, this paper studied how perceived control, learning opportunities and quantitative demands at work associate with workplace-locked-in (WP

Alzheimer’s disease (AD) is the most common form of dementia. Increased accumulations of senile plaques and tangles are the known neuropathological hallmarks of AD. However, the exact triggers for such protein accumulations, leading to cognitive impairment and important morphological alteration in AD, are still elusive. Ageing and genetic risk factors do not completely explain the global increase

Coherent operation of gate-voltage-controlled hybrid transmon qubits (gatemons) based on semiconductor nanowires was recently demonstrated. Here we experimentally investigate the anharmonicity in epitaxial InAs-Al Josephson junctions, a key parameter for their use as a qubit. Anharmonicity is found to be reduced by roughly a factor of 2 compared to conventional metallic junctions and dependent on

Socioeconomic, ethnic and gender disparities in Chronic Obstructive Pulmonary Disease (COPD) risk are well established but no studies have applied multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) within an intersectional framework to study this outcome. We study individuals at the first level of analysis and combinations of multiple social and demographic catego

This thesis describes optical and electrical modelling of vertically oriented III-V semiconductor nanowire array solar cells (NWASCs).In the optical studies, three-dimensional electromagnetic modelling was carried out with the scattering matrix method and the finite element method. Shockley–Queisser detailed balance analysis was first applied to a dual-junction NWASC in which both junctions were w